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- W2899694020 endingPage "1221" @default.
- W2899694020 startingPage "1211" @default.
- W2899694020 abstract "Introduction: The field of nanomedicine, utilizing nano-sized vehicles (nanoparticles and nanofibers) for targeted local drug delivery, has a promising future. This is dependent on the ability to analyze the chemical and physical properties of these drug carriers at the nanoscale and hence atomic force microscopy (AFM), a high-resolution imaging and local force-measurement technique, is ideally suited.Areas covered: Following a brief introduction to the technique, the review describes how AFM has been used in selected publications from 2015 to 2018 to characterize nanoparticles and nanofibers as drug delivery vehicles. These sections are ordered into areas of increasing AFM complexity: imaging/particle sizing, surface roughness/quantitative analysis of images, and analysis of force curves (to extract nanoindentation and adhesion data).Expert opinion: AFM imaging/sizing is used extensively for the characterization of nanoparticle and nanofiber drug delivery vehicles, with surface roughness and nanomechanical/adhesion data acquisition being less common. The field is progressing into combining AFM with other techniques, notably SEM, ToF-SIMS, Raman, Confocal, and UV. Current limitations include a 50 nm resolution limit of nanoparticles imaged within live cells and AFM tip-induced activation of cytoskeleton proteins. Following drug release real-time with AFM-spectroscopic techniques and studying drug interactions on cell receptors appear to be on the horizon." @default.
- W2899694020 created "2018-11-16" @default.
- W2899694020 creator A5024238182 @default.
- W2899694020 creator A5024822764 @default.
- W2899694020 creator A5047964149 @default.
- W2899694020 date "2018-11-20" @default.
- W2899694020 modified "2023-10-18" @default.
- W2899694020 title "Characterization of drug delivery vehicles using atomic force microscopy: current status" @default.
- W2899694020 cites W126474219 @default.
- W2899694020 cites W1519055819 @default.
- W2899694020 cites W1566345836 @default.
- W2899694020 cites W1572579287 @default.
- W2899694020 cites W1654592795 @default.
- W2899694020 cites W1831251608 @default.
- W2899694020 cites W1967160349 @default.
- W2899694020 cites W1969895991 @default.
- W2899694020 cites W1970940882 @default.
- W2899694020 cites W1972870700 @default.
- W2899694020 cites W1978252041 @default.
- W2899694020 cites W1981264689 @default.
- W2899694020 cites W1981477019 @default.
- W2899694020 cites W1982772747 @default.
- W2899694020 cites W1983684958 @default.
- W2899694020 cites W1984262548 @default.
- W2899694020 cites W1984696146 @default.
- W2899694020 cites W1987190257 @default.
- W2899694020 cites W1987843843 @default.
- W2899694020 cites W1997552417 @default.
- W2899694020 cites W2002255681 @default.
- W2899694020 cites W2007007455 @default.
- W2899694020 cites W2015716478 @default.
- W2899694020 cites W2021684550 @default.
- W2899694020 cites W2024550024 @default.
- W2899694020 cites W2024567131 @default.
- W2899694020 cites W2024745748 @default.
- W2899694020 cites W2026101543 @default.
- W2899694020 cites W2030701238 @default.
- W2899694020 cites W2039434763 @default.
- W2899694020 cites W2039763268 @default.
- W2899694020 cites W2046012539 @default.
- W2899694020 cites W2075933756 @default.
- W2899694020 cites W2088780861 @default.
- W2899694020 cites W2092203634 @default.
- W2899694020 cites W2093192991 @default.
- W2899694020 cites W2104053703 @default.
- W2899694020 cites W2107946552 @default.
- W2899694020 cites W2115936772 @default.
- W2899694020 cites W2133748730 @default.
- W2899694020 cites W2136904680 @default.
- W2899694020 cites W2149220545 @default.
- W2899694020 cites W2150309717 @default.
- W2899694020 cites W2150903279 @default.
- W2899694020 cites W2154469143 @default.
- W2899694020 cites W2154873102 @default.
- W2899694020 cites W2168734706 @default.
- W2899694020 cites W2205810849 @default.
- W2899694020 cites W2225070830 @default.
- W2899694020 cites W2240031186 @default.
- W2899694020 cites W2272425801 @default.
- W2899694020 cites W2272722996 @default.
- W2899694020 cites W2283768019 @default.
- W2899694020 cites W2288948224 @default.
- W2899694020 cites W2291482471 @default.
- W2899694020 cites W2301624354 @default.
- W2899694020 cites W2322363934 @default.
- W2899694020 cites W2330719602 @default.
- W2899694020 cites W2339603566 @default.
- W2899694020 cites W2344023998 @default.
- W2899694020 cites W2408968133 @default.
- W2899694020 cites W2412490572 @default.
- W2899694020 cites W2421275313 @default.
- W2899694020 cites W2527757661 @default.
- W2899694020 cites W2535104527 @default.
- W2899694020 cites W2540034041 @default.
- W2899694020 cites W2567244672 @default.
- W2899694020 cites W2581085293 @default.
- W2899694020 cites W2594815648 @default.
- W2899694020 cites W2599718686 @default.
- W2899694020 cites W2606462493 @default.
- W2899694020 cites W2607114305 @default.
- W2899694020 cites W2622676194 @default.
- W2899694020 cites W2627897466 @default.
- W2899694020 cites W2727899900 @default.
- W2899694020 cites W2733296761 @default.
- W2899694020 cites W2738347104 @default.
- W2899694020 cites W2742614799 @default.
- W2899694020 cites W2744911268 @default.
- W2899694020 cites W2744926260 @default.
- W2899694020 cites W2751652674 @default.
- W2899694020 cites W2751932095 @default.
- W2899694020 cites W2753882592 @default.
- W2899694020 cites W2759215993 @default.
- W2899694020 cites W2765373444 @default.
- W2899694020 cites W2765420341 @default.
- W2899694020 cites W2765574382 @default.
- W2899694020 cites W2782403797 @default.
- W2899694020 cites W2793009926 @default.
- W2899694020 cites W2796680085 @default.