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- W2899796006 abstract "Endocrine complications are frequently observed in childhood cancer survivors (CCS); in many instances, these complications develop months to years after the completion of cancer therapy. The estimated prevalence of endocrine late effects is 50% among CCS; the main risk factors are external beam radiation that includes key endocrine organs (the hypothalamus/pituitary, thyroid and gonads) and/or alkylating agents. Novel agents targeting tumor growth have increased the options available to a small number of patients albeit with the need for treatment over long periods of time. Some of these agents, such as certain tyrosine kinase inhibitors and immune system modulators have been shown to cause permanent endocrine deficits. This chapter offers a brief summary of the conventional treatment strategies for the most common cancers of childhood and a brief overview of the endocrine late effects most commonly associated with these exposures. The impact of targeted therapies on the endocrine system will also be discussed. The aim of this chapter is to provide basic guidance to the consulting pediatric endocrinologist in preparation for the clinical encounter with a CCS. A more detailed discussion of the management of specific endocrine late effects can be found in the other chapters in this series." @default.
- W2899796006 created "2018-11-16" @default.
- W2899796006 creator A5063077038 @default.
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- W2899796006 date "2018-11-07" @default.
- W2899796006 modified "2023-09-25" @default.
- W2899796006 title "Childhood Cancer Treatments and Associated Endocrine Late Effects: A Concise Guide for the Pediatric Endocrinologist" @default.
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- W2899796006 cites W1970139033 @default.
- W2899796006 cites W1976730498 @default.
- W2899796006 cites W1979515666 @default.
- W2899796006 cites W1981588870 @default.
- W2899796006 cites W1989180664 @default.
- W2899796006 cites W1991838073 @default.
- W2899796006 cites W1993020692 @default.
- W2899796006 cites W1995125767 @default.
- W2899796006 cites W2004448368 @default.
- W2899796006 cites W2008349873 @default.
- W2899796006 cites W2011314189 @default.
- W2899796006 cites W2011811997 @default.
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- W2899796006 cites W2014432477 @default.
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- W2899796006 cites W2031256781 @default.
- W2899796006 cites W2048576559 @default.
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- W2899796006 cites W2053055986 @default.
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- W2899796006 cites W2084345572 @default.
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- W2899796006 doi "https://doi.org/10.1159/000493943" @default.
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