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- W2899924452 abstract "The accurate quantification of microbial growth dynamics for species without complete genome sequences is biologically important, but computationally challenging in metagenomics. Here we present dynamic estimator of microbial communities (DEMIC; https://sourceforge.net/projects/demic/ ), a multi-sample algorithm based on contigs and coverage values, to infer the relative distances of contigs from the replication origin and to accurately compare bacterial growth rates between samples. We demonstrate robust performances of DEMIC for various sample sizes and assembly qualities using multiple synthetic and real datasets. DEMIC uses contigs and coverage data to compare growth rates between bacterial samples." @default.
- W2899924452 created "2018-11-16" @default.
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- W2899924452 date "2018-11-12" @default.
- W2899924452 modified "2023-10-03" @default.
- W2899924452 title "Quantifying and comparing bacterial growth dynamics in multiple metagenomic samples" @default.
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- W2899924452 doi "https://doi.org/10.1038/s41592-018-0182-0" @default.
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