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• W2899951921 abstract "In the present study, 60 patients were selected for the study. There were 41 (68.3%) males and 19 (31.7%) females. The minimum age of male was 34 years and the maximum age was 70 years. The minimum age of female was 30 years and the maximum age was 65 years. These patients were planned for radiotherapy. Cobalt- 60 equipment was used for radiation treatment. Radiation source, modality, field size, treatment areas, total planned dose, number of fractions, days of irradiation was recorded in the structured proforma prepared for the study. The 60 patients were selected for the study all the patients were given habit counseling regarding stopping of thehabit of the tobacco and were advised on basic oral hygiene. These 60 patients were randomly divided into three groups.Twenty patients in Group 1 were instructed to rinse with 20 ml of pure natural honey, 15 minutes before, 15 minutes after and 6 hours post-RT, during the course of radiotherapy. Twenty patients in Group 2 were instructed to rinse with 15 ml of 0.15%w/v benzydamine hydrochloride, 15 minutes before, 15 minutes after and 6 hours post-RT, during the course of radiotherapy. Twenty patients in Group 3 were instructed to rinse with 15 ml of 0.9% normal saline, 15 minutes before, 15 minutes after and 6 hours post-RT, during the course of radiotherapy.The onset of Grade I (WHO Mucositis Grading) was clinically observed in all the 3 groups, and severity is clinically observed by the days of onset of grades II, III & IV in the 3 groups and also the number of patients with more severe clinical and functional grades of III & IV.The onset of grades I, II, III &IV were compared within groups. The grades during end of post-RT First week and Second week were compared between groups.Statistical analysis were done using SPSS version 15 days of onset of grades I, II, III & IV were compared between groups 1, 2 & 3. From the presence study, we found usefulness of pure natural honey in the management of symptomatic radiation mucositis. As this agent is effective in radiation mucositis, the same treatment could be useful in the management of chemotherapy-induced oral stomatitis/mucositis and in mucositis of bone marrow transplant patients. The philosophy of management in the above conditions is similar. The further issue in the use of medicinal honey is quality assurance of natural honey-which might be different in different geographic locations-and the source of pollens. As the future multi-modality approach to cancer lies in chemo-radiotherapy and altered fractionation schemes, prevention of oral mucositis is very important in its management. Honey could be a simple, potent and inexpensive agent, which is easily available, especially in the present Indian scenario for the management of this morbidity. However, further randomized studies are essential to validate our findings." @default.
• W2899951921 created "2018-11-16" @default.
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• W2899951921 date "2011-04-01" @default.
• W2899951921 modified "2023-09-27" @default.
• W2899951921 title "Evaluating the Effectiveness of Topical Application of Pure Natural Honey and Benzydamine Hydrochloride on Radiation - Induced Mucositis" @default.
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