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- W2899973398 abstract "A novel methodology is presented for the synthesis of 3-substituted 2-thioxo-2,3-dihydroquinazolin-4(1H)-one derivatives based on an efficient tandem multicomponent reaction using copper bromide as catalyst. This methodology is based on the multicomponent one-pot reaction of methyl 2-bromobenzoate, phenylisothiocyanate derivatives and sodium azide in the presence of copper bromide and l-proline under basic conditions. To show the generality of the method, various phenylisothiocyanates bearing electron-donating or electron-withdrawing functionalities were used and the desired products were obtained in high isolated yields." @default.
- W2899973398 created "2018-11-16" @default.
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- W2899973398 date "2018-11-07" @default.
- W2899973398 modified "2023-09-26" @default.
- W2899973398 title "CuBr-catalysed one-pot multicomponent synthesis of 3-substituted 2-thioxo-2,3-dihydroquinazolin-4(1<i>H</i> )-one derivatives" @default.
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- W2899973398 doi "https://doi.org/10.1002/aoc.4635" @default.
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