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- W2899976593 abstract "Glycosylation is a post-translational modification that is involved in the regulation of many biological processes. The glycosylation pattern in cancer cells differs from that in normal cells. One of the main alterations that has been observed in several cancers is the increase of sialic acids at the end of the glycan. The increase of sialic acids and other alterations affect development and progression of tumors and are found to play an important role in cancer invasiveness and metastasis. Molecularly imprinted polymers (MIPs) are synthetic recognition elements that show high selectivity and affinity for their targets. These polymers show promising applications in detection methods for cancer cells. In this study newly synthesized MIPs, labelled with a nitrobenzoxadiazole (NBD) fluorophore, are investigated for their specificity and utility in the detection of cancer cell-related sialic acids." @default.
- W2899976593 created "2018-11-16" @default.
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- W2899976593 date "2018-01-01" @default.
- W2899976593 modified "2023-09-27" @default.
- W2899976593 title "Application of novel tumor cell glycan-specific nanoprobes for detecting and targeting breast and prostate cancer" @default.
- W2899976593 hasPublicationYear "2018" @default.
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