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- W2900083287 abstract "Abstract Health professionals consider the evaluation of eating habits to be challenging, given the potential biases of dietary questionnaires based on self-reported data. Circulating carotenoid concentrations are reliable biomarkers of dietary carotenoid intake and could be useful in the validation of dietary assessment tools. However, there is a sex difference in circulating carotenoids, with women displaying higher concentrations compared with men independent of intake. The aim of the present study was to identify the correlates of plasma carotenoid concentrations among men ( n 155) and women ( n 110) enrolled in six fully controlled dietary interventions with varying dietary carotenoid intakes. We looked at the associations of post-intervention fasting plasma carotenoid concentrations ( α -carotene, β -carotene, β -cryptoxanthin, lutein, lycopene and zeaxanthin) with physical and metabolic characteristics. We found that increased body weight ( r –0·47, P <0·0001) and waist circumference ( r –0·46, P <0·0001) were associated with lower plasma total carotenoid concentrations, while elevated plasma LDL-cholesterol ( r 0·49, P <0·0001) and HDL-cholesterol ( r 0·50, P <0·0001) concentrations were correlated with higher total carotenoids in plasma. Women had significantly higher plasma total carotenoid concentrations compared with men, despite significantly lower dietary carotenoid intake. Adjustment of circulating carotenoid concentrations for plasma HDL-cholesterol eliminated sex difference in plasma carotenoid concentrations. Our results suggest that physical characteristics as well as plasma lipids are associated with circulating carotenoid concentrations and that these variables should be taken into account when using plasma carotenoids as biomarkers for food intake in men and women." @default.
- W2900083287 created "2018-11-16" @default.
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- W2900083287 date "2018-11-05" @default.
- W2900083287 modified "2023-10-13" @default.
- W2900083287 title "Correlates of the difference in plasma carotenoid concentrations between men and women" @default.
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- W2900083287 doi "https://doi.org/10.1017/s0007114518003045" @default.
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