Matches in SemOpenAlex for { <https://semopenalex.org/work/W2900095969> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2900095969 endingPage "742" @default.
- W2900095969 startingPage "735" @default.
- W2900095969 abstract "Most fungal infections found in wounds are secondary or superadded, and are generally benign in their clinical course in healthy individuals, with the exception of mucormycosis. This is a life-threatening infection caused by fungi of the order Mucorales. Primary cutaneous disease may occur following traumatic implantation of spores, or use of contaminated bandages, or as a complication of extensive burns, diabetic acidosis and other specific immunocompromised conditions. The clinical spectrum is highly non-specific and is often triggered by seemingly innocuous trauma. The superficial vesicles or patchy erythema rapidly degrade to haemorrhagic necrosis and rapidly progressive gangrenous lesion. The problem with diagnosing mucormycosis remains, therefore, that the condition has poor clinical indicators and requires reliance on microscopy and fungal culture. Management starts with a clinical suspicion, taking into account the risk factors and lack of response to first-line agents, as well as an aggressive clinical course. Treatment is multimodal, with medical correction of the risk factors and optimisation of limiting factors, such as diabetes, neutropenia and immunosuppressants. Treatment generally involves radical and repetitive surgical debridement, intravenous amphotericin B with monitoring of the nephrotoxicity, along with adjuvant modalities, such as hyperbaric oxygen therapy, colony stimulating factor, interferons gamma and white blood cell transfusion. Successful courses of therapy typically last 4–6 weeks and require cumulative doses that are equivalent to >2g of amphotericin B deoxycholate." @default.
- W2900095969 created "2018-11-16" @default.
- W2900095969 creator A5003444414 @default.
- W2900095969 creator A5004359706 @default.
- W2900095969 creator A5014031919 @default.
- W2900095969 creator A5051134344 @default.
- W2900095969 creator A5054143208 @default.
- W2900095969 creator A5072042162 @default.
- W2900095969 date "2018-11-02" @default.
- W2900095969 modified "2023-09-27" @default.
- W2900095969 title "Treating mucormycosis using a multimodality approach: a case series" @default.
- W2900095969 cites W1977911228 @default.
- W2900095969 cites W2061033767 @default.
- W2900095969 cites W2066954795 @default.
- W2900095969 cites W2070944246 @default.
- W2900095969 cites W2106619970 @default.
- W2900095969 cites W2113690161 @default.
- W2900095969 cites W2113977119 @default.
- W2900095969 cites W2116475151 @default.
- W2900095969 cites W2127804950 @default.
- W2900095969 cites W2138571658 @default.
- W2900095969 cites W2139894595 @default.
- W2900095969 cites W2140096322 @default.
- W2900095969 cites W2140682278 @default.
- W2900095969 cites W2142996250 @default.
- W2900095969 cites W2144030592 @default.
- W2900095969 cites W2146851458 @default.
- W2900095969 cites W2149162200 @default.
- W2900095969 cites W2510314340 @default.
- W2900095969 cites W2596215052 @default.
- W2900095969 doi "https://doi.org/10.12968/jowc.2018.27.11.735" @default.
- W2900095969 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30398934" @default.
- W2900095969 hasPublicationYear "2018" @default.
- W2900095969 type Work @default.
- W2900095969 sameAs 2900095969 @default.
- W2900095969 citedByCount "4" @default.
- W2900095969 countsByYear W29000959692020 @default.
- W2900095969 countsByYear W29000959692021 @default.
- W2900095969 countsByYear W29000959692022 @default.
- W2900095969 crossrefType "journal-article" @default.
- W2900095969 hasAuthorship W2900095969A5003444414 @default.
- W2900095969 hasAuthorship W2900095969A5004359706 @default.
- W2900095969 hasAuthorship W2900095969A5014031919 @default.
- W2900095969 hasAuthorship W2900095969A5051134344 @default.
- W2900095969 hasAuthorship W2900095969A5054143208 @default.
- W2900095969 hasAuthorship W2900095969A5072042162 @default.
- W2900095969 hasConcept C141071460 @default.
- W2900095969 hasConcept C16005928 @default.
- W2900095969 hasConcept C2776694085 @default.
- W2900095969 hasConcept C2777063308 @default.
- W2900095969 hasConcept C2777292849 @default.
- W2900095969 hasConcept C2777438270 @default.
- W2900095969 hasConcept C2779121184 @default.
- W2900095969 hasConcept C2779548794 @default.
- W2900095969 hasConcept C2779629538 @default.
- W2900095969 hasConcept C71924100 @default.
- W2900095969 hasConcept C81182388 @default.
- W2900095969 hasConceptScore W2900095969C141071460 @default.
- W2900095969 hasConceptScore W2900095969C16005928 @default.
- W2900095969 hasConceptScore W2900095969C2776694085 @default.
- W2900095969 hasConceptScore W2900095969C2777063308 @default.
- W2900095969 hasConceptScore W2900095969C2777292849 @default.
- W2900095969 hasConceptScore W2900095969C2777438270 @default.
- W2900095969 hasConceptScore W2900095969C2779121184 @default.
- W2900095969 hasConceptScore W2900095969C2779548794 @default.
- W2900095969 hasConceptScore W2900095969C2779629538 @default.
- W2900095969 hasConceptScore W2900095969C71924100 @default.
- W2900095969 hasConceptScore W2900095969C81182388 @default.
- W2900095969 hasIssue "11" @default.
- W2900095969 hasLocation W29000959691 @default.
- W2900095969 hasLocation W29000959692 @default.
- W2900095969 hasOpenAccess W2900095969 @default.
- W2900095969 hasPrimaryLocation W29000959691 @default.
- W2900095969 hasRelatedWork W1994127247 @default.
- W2900095969 hasRelatedWork W2059421293 @default.
- W2900095969 hasRelatedWork W2093515679 @default.
- W2900095969 hasRelatedWork W2109483843 @default.
- W2900095969 hasRelatedWork W2144611891 @default.
- W2900095969 hasRelatedWork W2324146982 @default.
- W2900095969 hasRelatedWork W2369162477 @default.
- W2900095969 hasRelatedWork W2419367854 @default.
- W2900095969 hasRelatedWork W4200190897 @default.
- W2900095969 hasRelatedWork W62711790 @default.
- W2900095969 hasVolume "27" @default.
- W2900095969 isParatext "false" @default.
- W2900095969 isRetracted "false" @default.
- W2900095969 magId "2900095969" @default.
- W2900095969 workType "article" @default.