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- W2900113285 abstract "Salvia miltiorrhiza has been widely used in Asia for medicinal purposes for >1000 years due to the high levels of bioactive constituents it contains. In this study, a simple and rapid ultrasound-assisted liquid extraction (5 min) was applied for the extraction of these bioactive constituents. The extracts were analyzed by using rapid ultrahigh performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) with simultaneous positive and negative electrospray ionization in a single analytical run. Eight analytes were separated within 2.2 min during 6 min of run time with UHPLC-MS/MS operated in multiple reaction monitoring (MRM) mode. The concentration of salvianolic acids and tanshinones in the different organs of different varieties of Salvia miltiorrhiza ranged from 6.4 to 382.1 mg/g and 0.03 to 31.7 mg/g, respectively. To the best of our knowledge, this is the first report to characterize the tanshinone compounds found in the flower and stem/leaf of Salvia miltiorrhiza by UHPLC-MS/MS." @default.
- W2900113285 created "2018-11-16" @default.
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- W2900113285 date "2019-01-01" @default.
- W2900113285 modified "2023-10-16" @default.
- W2900113285 title "Rapid determination of bioactive compounds in the different organs of Salvia Miltiorrhiza by UPLC-MS/MS" @default.
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- W2900113285 doi "https://doi.org/10.1016/j.jchromb.2018.11.006" @default.
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