FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2900118411> ?p ?o ?g. }

• W2900118411 endingPage "198" @default.
• W2900118411 startingPage "193" @default.
• W2900118411 abstract "Salmonella are causes of livestock, poultry, and other animal diseases but they also have the potential to infect people. Currently, antibiotics are the first choice for treatment of Salmonella infections. Thus, the utility of phage has become the research focus for scientists for several reasons. There are efficient, non-toxic, ubiquitous, easy to prepare and can result in the lysis of host bacteria. In this study, a broad spectrum bacteriophage of Salmonella was isolated from the fecal samples of a poultryfarm and we studied the morphological aspects, thermal stability, pH stability, optimal multiplicity of infection (MOI), and one-step growth curve of this phage. This phage was named Salmonella phage SaFB14 and lysed 54.12%(105/194)Salmonella spp. SaFB14 belongs to the Siphoviridae and has a polyhedron head with a diameter approximating 60 × 60 nm and a tail approximating 140 nm. The optimum growth temperature was 37 °C and maintained high activity over a widepH range(pH3-10) with an optimum of pH 7.0. The optimal MOI was 0.1. A one-step growth curve showed that its latency time was 10 min, burst time was 70 min, and burst was 23 particles. In order to study the therapeutic effect of phage SaFB14 in infected mice, mice were challenged with 2 × 109 CFU/mouse Salmonella (cs20130523-001-1). Each mouse was injected to 2 × 1010 PFU SaFB14 1 h later. SaFB14 protected 40% of mice from infection. Then, the same dose of phage was given to mice for 3 days continuously. After 3 days treatment, the survival rate increased to 60%.In conclusion, phage SaFB14 showed wide host range and good activity in vivo, it is promising against diseases caused by Salmonella." @default.
• W2900118411 created "2018-11-16" @default.
• W2900118411 creator A5000844607 @default.
• W2900118411 creator A5002237778 @default.
• W2900118411 creator A5005453338 @default.
• W2900118411 creator A5013960320 @default.
• W2900118411 creator A5023930365 @default.
• W2900118411 creator A5025696708 @default.
• W2900118411 creator A5028464213 @default.
• W2900118411 creator A5043593357 @default.
• W2900118411 creator A5049597728 @default.
• W2900118411 creator A5059673434 @default.
• W2900118411 creator A5069322444 @default.
• W2900118411 creator A5081465525 @default.
• W2900118411 date "2019-01-01" @default.
• W2900118411 modified "2023-09-27" @default.
• W2900118411 title "Isolation and characterization of a broad-spectrum phage of multiple drug resistant Salmonella and its therapeutic utility in mice" @default.
• W2900118411 cites W1974394752 @default.
• W2900118411 cites W1974702731 @default.
• W2900118411 cites W1978933046 @default.
• W2900118411 cites W1982381985 @default.
• W2900118411 cites W1986717059 @default.
• W2900118411 cites W2001708469 @default.
• W2900118411 cites W2002516891 @default.
• W2900118411 cites W2013330518 @default.
• W2900118411 cites W2014020659 @default.
• W2900118411 cites W2014783118 @default.
• W2900118411 cites W2018707178 @default.
• W2900118411 cites W2019358577 @default.
• W2900118411 cites W2026733066 @default.
• W2900118411 cites W2047019892 @default.
• W2900118411 cites W2059702605 @default.
• W2900118411 cites W2108748592 @default.
• W2900118411 cites W2110282351 @default.
• W2900118411 cites W2117681922 @default.
• W2900118411 cites W2120108890 @default.
• W2900118411 cites W2126229005 @default.
• W2900118411 cites W2128591134 @default.
• W2900118411 cites W2132954220 @default.
• W2900118411 cites W2141169016 @default.
• W2900118411 cites W2151587656 @default.
• W2900118411 cites W2152462726 @default.
• W2900118411 cites W2171539394 @default.
• W2900118411 cites W2317030375 @default.
• W2900118411 cites W2416798811 @default.
• W2900118411 cites W2473130540 @default.
• W2900118411 cites W2497298961 @default.
• W2900118411 cites W25248026 @default.
• W2900118411 cites W2579491213 @default.
• W2900118411 cites W2622866636 @default.
• W2900118411 cites W2767213641 @default.
• W2900118411 cites W2770270574 @default.
• W2900118411 cites W2771012862 @default.
• W2900118411 cites W2782730876 @default.
• W2900118411 doi "https://doi.org/10.1016/j.micpath.2018.10.042" @default.
• W2900118411 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30408490" @default.
• W2900118411 hasPublicationYear "2019" @default.
• W2900118411 type Work @default.
• W2900118411 sameAs 2900118411 @default.
• W2900118411 citedByCount "34" @default.
• W2900118411 countsByYear W29001184112018 @default.
• W2900118411 countsByYear W29001184112019 @default.
• W2900118411 countsByYear W29001184112020 @default.
• W2900118411 countsByYear W29001184112021 @default.
• W2900118411 countsByYear W29001184112022 @default.
• W2900118411 countsByYear W29001184112023 @default.
• W2900118411 crossrefType "journal-article" @default.
• W2900118411 hasAuthorship W2900118411A5000844607 @default.
• W2900118411 hasAuthorship W2900118411A5002237778 @default.
• W2900118411 hasAuthorship W2900118411A5005453338 @default.
• W2900118411 hasAuthorship W2900118411A5013960320 @default.
• W2900118411 hasAuthorship W2900118411A5023930365 @default.
• W2900118411 hasAuthorship W2900118411A5025696708 @default.
• W2900118411 hasAuthorship W2900118411A5028464213 @default.
• W2900118411 hasAuthorship W2900118411A5043593357 @default.
• W2900118411 hasAuthorship W2900118411A5049597728 @default.
• W2900118411 hasAuthorship W2900118411A5059673434 @default.
• W2900118411 hasAuthorship W2900118411A5069322444 @default.
• W2900118411 hasAuthorship W2900118411A5081465525 @default.
• W2900118411 hasConcept C104317684 @default.
• W2900118411 hasConcept C153911025 @default.
• W2900118411 hasConcept C159047783 @default.
• W2900118411 hasConcept C203233990 @default.
• W2900118411 hasConcept C2522874641 @default.
• W2900118411 hasConcept C2776441376 @default.
• W2900118411 hasConcept C2778303719 @default.
• W2900118411 hasConcept C2779256223 @default.
• W2900118411 hasConcept C2781065037 @default.
• W2900118411 hasConcept C501593827 @default.
• W2900118411 hasConcept C523546767 @default.
• W2900118411 hasConcept C54355233 @default.
• W2900118411 hasConcept C547475151 @default.
• W2900118411 hasConcept C55493867 @default.
• W2900118411 hasConcept C57409179 @default.
• W2900118411 hasConcept C86803240 @default.
• W2900118411 hasConcept C89423630 @default.
• W2900118411 hasConceptScore W2900118411C104317684 @default.
• W2900118411 hasConceptScore W2900118411C153911025 @default.

• next