Matches in SemOpenAlex for { <https://semopenalex.org/work/W2900237256> ?p ?o ?g. }
- W2900237256 endingPage "88" @default.
- W2900237256 startingPage "78" @default.
- W2900237256 abstract "Chlorogenic acid as a constituent of coffee is consumed regularly in the human diet. Chlorogenic acid intake has been associated with decreased risk of cardiovascular disease and type 2 diabetes. We hypothesized that chlorogenic acid would improve cardiovascular, liver, and metabolic responses in a rat model of metabolic syndrome induced by a high-carbohydrate, high-fat diet. Male Wistar rats (8-9 weeks old, 335 ± 2 g, n = 48) were divided into 4 groups and fed with corn starch diet (16 weeks); corn starch diet with chlorogenic acid in food for the last 8 weeks; high-carbohydrate, high-fat diet (16 weeks); or high-carbohydrate, high-fat diet with chlorogenic acid (~100 mg/kg/d) in food for the last 8 weeks. In high-carbohydrate, high-fat diet–fed rats, chlorogenic acid reduced energy intake and food efficiency to reduce visceral fat, especially retroperitoneal fat, and abdominal circumference; reversed the elevated systolic blood pressure; and attenuated left ventricular diastolic stiffness with reduced collagen deposition and infiltration of inflammatory cells in the left ventricle. Chlorogenic acid decreased inflammation and fat deposition in the liver along with reduced plasma liver enzyme activities of obese rats but did not change the plasma lipid profile. Chlorogenic acid increased diversity of gut microbiota, which may improve overall metabolism in the body. Thus, chronic dietary chlorogenic acid attenuated diet-induced inflammation as well as cardiovascular, liver, and metabolic changes, suggesting that chlorogenic acid has potential for further clinical evaluation." @default.
- W2900237256 created "2018-11-16" @default.
- W2900237256 creator A5015311464 @default.
- W2900237256 creator A5077330518 @default.
- W2900237256 creator A5081497233 @default.
- W2900237256 date "2019-02-01" @default.
- W2900237256 modified "2023-10-17" @default.
- W2900237256 title "Chlorogenic acid attenuates high-carbohydrate, high-fat diet–induced cardiovascular, liver, and metabolic changes in rats" @default.
- W2900237256 cites W1503060668 @default.
- W2900237256 cites W1530048637 @default.
- W2900237256 cites W1928460949 @default.
- W2900237256 cites W1932390491 @default.
- W2900237256 cites W1966348304 @default.
- W2900237256 cites W1967923229 @default.
- W2900237256 cites W1979815711 @default.
- W2900237256 cites W1981275437 @default.
- W2900237256 cites W2006702634 @default.
- W2900237256 cites W2011896793 @default.
- W2900237256 cites W2016275317 @default.
- W2900237256 cites W2019076819 @default.
- W2900237256 cites W2021241382 @default.
- W2900237256 cites W2030628693 @default.
- W2900237256 cites W2041136224 @default.
- W2900237256 cites W2042967579 @default.
- W2900237256 cites W2049812779 @default.
- W2900237256 cites W2075346438 @default.
- W2900237256 cites W2083260532 @default.
- W2900237256 cites W2086732325 @default.
- W2900237256 cites W2088276703 @default.
- W2900237256 cites W2092209599 @default.
- W2900237256 cites W2094685285 @default.
- W2900237256 cites W2101964276 @default.
- W2900237256 cites W2117991022 @default.
- W2900237256 cites W2121836743 @default.
- W2900237256 cites W2127507974 @default.
- W2900237256 cites W2130794819 @default.
- W2900237256 cites W2138711123 @default.
- W2900237256 cites W2164564178 @default.
- W2900237256 cites W2165259958 @default.
- W2900237256 cites W2168244623 @default.
- W2900237256 cites W2216606325 @default.
- W2900237256 cites W2276108661 @default.
- W2900237256 cites W2314924383 @default.
- W2900237256 cites W2592338368 @default.
- W2900237256 cites W2605131570 @default.
- W2900237256 cites W2606868394 @default.
- W2900237256 cites W2612582931 @default.
- W2900237256 cites W2725511979 @default.
- W2900237256 cites W2734005393 @default.
- W2900237256 cites W2767209834 @default.
- W2900237256 cites W2768608807 @default.
- W2900237256 cites W2769082931 @default.
- W2900237256 cites W290107511 @default.
- W2900237256 doi "https://doi.org/10.1016/j.nutres.2018.11.002" @default.
- W2900237256 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30803509" @default.
- W2900237256 hasPublicationYear "2019" @default.
- W2900237256 type Work @default.
- W2900237256 sameAs 2900237256 @default.
- W2900237256 citedByCount "85" @default.
- W2900237256 countsByYear W29002372562019 @default.
- W2900237256 countsByYear W29002372562020 @default.
- W2900237256 countsByYear W29002372562021 @default.
- W2900237256 countsByYear W29002372562022 @default.
- W2900237256 countsByYear W29002372562023 @default.
- W2900237256 crossrefType "journal-article" @default.
- W2900237256 hasAuthorship W2900237256A5015311464 @default.
- W2900237256 hasAuthorship W2900237256A5077330518 @default.
- W2900237256 hasAuthorship W2900237256A5081497233 @default.
- W2900237256 hasConcept C126322002 @default.
- W2900237256 hasConcept C134018914 @default.
- W2900237256 hasConcept C185592680 @default.
- W2900237256 hasConcept C2778977261 @default.
- W2900237256 hasConcept C2780117898 @default.
- W2900237256 hasConcept C31903555 @default.
- W2900237256 hasConcept C71924100 @default.
- W2900237256 hasConcept C86803240 @default.
- W2900237256 hasConceptScore W2900237256C126322002 @default.
- W2900237256 hasConceptScore W2900237256C134018914 @default.
- W2900237256 hasConceptScore W2900237256C185592680 @default.
- W2900237256 hasConceptScore W2900237256C2778977261 @default.
- W2900237256 hasConceptScore W2900237256C2780117898 @default.
- W2900237256 hasConceptScore W2900237256C31903555 @default.
- W2900237256 hasConceptScore W2900237256C71924100 @default.
- W2900237256 hasConceptScore W2900237256C86803240 @default.
- W2900237256 hasLocation W29002372561 @default.
- W2900237256 hasLocation W29002372562 @default.
- W2900237256 hasOpenAccess W2900237256 @default.
- W2900237256 hasPrimaryLocation W29002372561 @default.
- W2900237256 hasRelatedWork W1966504330 @default.
- W2900237256 hasRelatedWork W1966775726 @default.
- W2900237256 hasRelatedWork W1979139803 @default.
- W2900237256 hasRelatedWork W1991560548 @default.
- W2900237256 hasRelatedWork W2030889776 @default.
- W2900237256 hasRelatedWork W2037631372 @default.
- W2900237256 hasRelatedWork W2040058909 @default.
- W2900237256 hasRelatedWork W2063957970 @default.
- W2900237256 hasRelatedWork W2132898409 @default.
- W2900237256 hasRelatedWork W4249176446 @default.