FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2900251404> ?p ?o ?g. }

• W2900251404 endingPage "9" @default.
• W2900251404 startingPage "1" @default.
• W2900251404 abstract "Growing evidences have shown that particulate matter (PM) exposures during pregnancy are associated with impaired fetal development and adverse birth outcomes, possibly as a result of an exaggerated systemic oxidative stress and inflammation. Telomere length (TL) is strongly linked to biological age and is impacted by oxidative stress. We hypothesized that PM exposure during different time windows in the first trimester of pregnancy influences both mitochondrial DNA copy number (mtDNAcn), an established biomarker for oxidative stress, and TL. Maternal blood TL and mtDNAcn were analysed in 199 healthy pregnant women recruited at the 11th week of pregnancy by quantitative polymerase chain reaction. We also examined whether maternal mtDNAcn and TL were associated with fetal growth outcomes measured at the end of the first trimester of pregnancy (fetal heart rate, FHR; crown-rump length, CRL; and nuchal translucency, NT) and at delivery (birth weight, length, head circumference). The possible modifying effect of prepregnancy maternal body mass index was evaluated. PM 10 exposure during the first pregnancy trimester was associated with an increased maternal mtDNAcn and a reduced TL. As regards ultrasound fetal outcomes, both FHR and CRL were positively associated with PM 2.5 , whereas the association with FHR was confirmed only when examining PM 10 exposure. PM 10 was also associated with a reduced birth weight. While no association was found between mtDNAcn and CRL, we found a negative relationship between mtDNAcn and fetal CRL only in overweight women, whereas normal-weight women exhibited a positive, albeit nonsignificant, association. As abnormalities of growth in utero have been associated with postnatal childhood and adulthood onset diseases and as PM is a widespread pollutant relevant to the large majority of the human population and obesity a rising risk factor, our results, if confirmed in a larger population, might represent an important contribution towards the development of more targeted public health strategies." @default.
• W2900251404 created "2018-11-16" @default.
• W2900251404 creator A5001980972 @default.
• W2900251404 creator A5007836073 @default.
• W2900251404 creator A5014044281 @default.
• W2900251404 creator A5039615761 @default.
• W2900251404 creator A5040377654 @default.
• W2900251404 creator A5052831050 @default.
• W2900251404 creator A5058012426 @default.
• W2900251404 creator A5082765326 @default.
• W2900251404 creator A5085556320 @default.
• W2900251404 date "2018-11-05" @default.
• W2900251404 modified "2023-10-17" @default.
• W2900251404 title "Particulate Air Pollution, Blood Mitochondrial DNA Copy Number, and Telomere Length in Mothers in the First Trimester of Pregnancy: Effects on Fetal Growth" @default.
• W2900251404 cites W1774344187 @default.
• W2900251404 cites W1785546977 @default.
• W2900251404 cites W1876302624 @default.
• W2900251404 cites W1963787355 @default.
• W2900251404 cites W1975364410 @default.
• W2900251404 cites W1977426512 @default.
• W2900251404 cites W1978179719 @default.
• W2900251404 cites W1984119010 @default.
• W2900251404 cites W1988093972 @default.
• W2900251404 cites W1994873752 @default.
• W2900251404 cites W2012540366 @default.
• W2900251404 cites W2026761826 @default.
• W2900251404 cites W2032218106 @default.
• W2900251404 cites W2044015235 @default.
• W2900251404 cites W2047906382 @default.
• W2900251404 cites W2066976215 @default.
• W2900251404 cites W2067053129 @default.
• W2900251404 cites W2089782421 @default.
• W2900251404 cites W2093294355 @default.
• W2900251404 cites W2093384103 @default.
• W2900251404 cites W2094071170 @default.
• W2900251404 cites W2096673955 @default.
• W2900251404 cites W2098493446 @default.
• W2900251404 cites W2102412106 @default.
• W2900251404 cites W2114953326 @default.
• W2900251404 cites W2115712850 @default.
• W2900251404 cites W2118071672 @default.
• W2900251404 cites W2132578923 @default.
• W2900251404 cites W2143454089 @default.
• W2900251404 cites W2146137933 @default.
• W2900251404 cites W2150751323 @default.
• W2900251404 cites W2151647462 @default.
• W2900251404 cites W2153375305 @default.
• W2900251404 cites W2160621707 @default.
• W2900251404 cites W2161645641 @default.
• W2900251404 cites W2165215925 @default.
• W2900251404 cites W2227909488 @default.
• W2900251404 cites W2282686919 @default.
• W2900251404 cites W2318698569 @default.
• W2900251404 cites W2515386017 @default.
• W2900251404 cites W2553689564 @default.
• W2900251404 cites W2607820614 @default.
• W2900251404 cites W2622433117 @default.
• W2900251404 cites W2769779892 @default.
• W2900251404 cites W2804192736 @default.
• W2900251404 cites W31143131 @default.
• W2900251404 doi "https://doi.org/10.1155/2018/5162905" @default.
• W2900251404 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6247572" @default.
• W2900251404 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30524658" @default.
• W2900251404 hasPublicationYear "2018" @default.
• W2900251404 type Work @default.
• W2900251404 sameAs 2900251404 @default.
• W2900251404 citedByCount "32" @default.
• W2900251404 countsByYear W29002514042019 @default.
• W2900251404 countsByYear W29002514042020 @default.
• W2900251404 countsByYear W29002514042021 @default.
• W2900251404 countsByYear W29002514042022 @default.
• W2900251404 countsByYear W29002514042023 @default.
• W2900251404 crossrefType "journal-article" @default.
• W2900251404 hasAuthorship W2900251404A5001980972 @default.
• W2900251404 hasAuthorship W2900251404A5007836073 @default.
• W2900251404 hasAuthorship W2900251404A5014044281 @default.
• W2900251404 hasAuthorship W2900251404A5039615761 @default.
• W2900251404 hasAuthorship W2900251404A5040377654 @default.
• W2900251404 hasAuthorship W2900251404A5052831050 @default.
• W2900251404 hasAuthorship W2900251404A5058012426 @default.
• W2900251404 hasAuthorship W2900251404A5082765326 @default.
• W2900251404 hasAuthorship W2900251404A5085556320 @default.
• W2900251404 hasBestOaLocation W29002514041 @default.
• W2900251404 hasConcept C126322002 @default.
• W2900251404 hasConcept C131872663 @default.
• W2900251404 hasConcept C134018914 @default.
• W2900251404 hasConcept C16685009 @default.
• W2900251404 hasConcept C172680121 @default.
• W2900251404 hasConcept C2776151105 @default.
• W2900251404 hasConcept C2779234561 @default.
• W2900251404 hasConcept C2780221984 @default.
• W2900251404 hasConcept C42407357 @default.
• W2900251404 hasConcept C54355233 @default.
• W2900251404 hasConcept C66322754 @default.
• W2900251404 hasConcept C71924100 @default.
• W2900251404 hasConcept C86803240 @default.
• W2900251404 hasConceptScore W2900251404C126322002 @default.
• W2900251404 hasConceptScore W2900251404C131872663 @default.

• next