FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2900390765> ?p ?o ?g. }

• W2900390765 endingPage "646" @default.
• W2900390765 startingPage "636" @default.
• W2900390765 abstract "Goats (Capra hircus) are an important farm animal species. Copy number variation (CNV) represents a major source of genomic structural variation. We investigated the diversity of CNV distribution in goats using CaprineSNP50 genotyping data generated by the ADAPTmap Project. We identified 6286 putative CNVs in 1023 samples from 50 goat breeds using PennCNV. These CNVs were merged into 978 CNV regions, spanning ~262 Mb of total length and corresponding to ~8.96% of the goat genome. We then divided the samples into six subgroups per geographic distribution and constructed a comparative CNV map. Our results revealed a population differentiation in CNV across different geographical areas, including Western Asia, Eastern Mediterranean, Alpine & Northern Europe, Madagascar, Northwestern Africa, and Southeastern Africa groups. The results of a cluster heatmap analysis based on the CNV count per individual across different groups was generally consistent with the one generated from the SNP data, likely reflecting the population history of different goat breeds. We sought to determine the gene content of these CNV events and found several important CNV-overlapping genes (e.g. EDNRA, ADAMTS20, ASIP, KDM5B, ADAM8, DGAT1, CHRNB1, CLCN7, and EXOSC4), which are involved in local adaptations such as coat color, muscle development, metabolic processes, osteopetrosis, and embryonic development. Therefore, this research generated an extensive CNV map in the worldwide population of goat, which offers novel insight into the goat genome and its functional annotation." @default.
• W2900390765 created "2018-11-16" @default.
• W2900390765 creator A5002054724 @default.
• W2900390765 creator A5013692065 @default.
• W2900390765 creator A5018324670 @default.
• W2900390765 creator A5022723256 @default.
• W2900390765 creator A5029060394 @default.
• W2900390765 creator A5030835880 @default.
• W2900390765 creator A5036123607 @default.
• W2900390765 creator A5042919376 @default.
• W2900390765 creator A5050622690 @default.
• W2900390765 creator A5063292856 @default.
• W2900390765 creator A5065006335 @default.
• W2900390765 creator A5065537915 @default.
• W2900390765 creator A5073887323 @default.
• W2900390765 creator A5074049715 @default.
• W2900390765 creator A5074529700 @default.
• W2900390765 date "2018-11-06" @default.
• W2900390765 modified "2023-10-13" @default.
• W2900390765 title "Diversity of copy number variation in the worldwide goat population" @default.
• W2900390765 cites W1561398821 @default.
• W2900390765 cites W1567934730 @default.
• W2900390765 cites W1963534839 @default.
• W2900390765 cites W1965035453 @default.
• W2900390765 cites W1971580911 @default.
• W2900390765 cites W1984068087 @default.
• W2900390765 cites W1988614825 @default.
• W2900390765 cites W1994923386 @default.
• W2900390765 cites W1997790208 @default.
• W2900390765 cites W2021714239 @default.
• W2900390765 cites W2022066446 @default.
• W2900390765 cites W2031001784 @default.
• W2900390765 cites W2034197594 @default.
• W2900390765 cites W2035441954 @default.
• W2900390765 cites W2035947340 @default.
• W2900390765 cites W2064209400 @default.
• W2900390765 cites W2074956582 @default.
• W2900390765 cites W2077763475 @default.
• W2900390765 cites W2078859234 @default.
• W2900390765 cites W2081172215 @default.
• W2900390765 cites W2084143577 @default.
• W2900390765 cites W2085755265 @default.
• W2900390765 cites W2093044565 @default.
• W2900390765 cites W2098381128 @default.
• W2900390765 cites W2103355383 @default.
• W2900390765 cites W2110749464 @default.
• W2900390765 cites W2119444539 @default.
• W2900390765 cites W2124308998 @default.
• W2900390765 cites W2124429242 @default.
• W2900390765 cites W2128616554 @default.
• W2900390765 cites W2132885074 @default.
• W2900390765 cites W2145850350 @default.
• W2900390765 cites W2149681218 @default.
• W2900390765 cites W2153797859 @default.
• W2900390765 cites W2156131965 @default.
• W2900390765 cites W2157314782 @default.
• W2900390765 cites W2162927194 @default.
• W2900390765 cites W2164947706 @default.
• W2900390765 cites W2168650324 @default.
• W2900390765 cites W2310742581 @default.
• W2900390765 cites W2336072157 @default.
• W2900390765 cites W2463645467 @default.
• W2900390765 cites W2469261821 @default.
• W2900390765 cites W2471692635 @default.
• W2900390765 cites W2473550633 @default.
• W2900390765 cites W2523032102 @default.
• W2900390765 cites W2592623057 @default.
• W2900390765 cites W2594081754 @default.
• W2900390765 cites W2606904422 @default.
• W2900390765 cites W2614086901 @default.
• W2900390765 cites W2754505756 @default.
• W2900390765 cites W2755821105 @default.
• W2900390765 doi "https://doi.org/10.1038/s41437-018-0150-6" @default.
• W2900390765 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6462038" @default.
• W2900390765 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30401973" @default.
• W2900390765 hasPublicationYear "2018" @default.
• W2900390765 type Work @default.
• W2900390765 sameAs 2900390765 @default.
• W2900390765 citedByCount "36" @default.
• W2900390765 countsByYear W29003907652019 @default.
• W2900390765 countsByYear W29003907652020 @default.
• W2900390765 countsByYear W29003907652021 @default.
• W2900390765 countsByYear W29003907652022 @default.
• W2900390765 countsByYear W29003907652023 @default.
• W2900390765 crossrefType "journal-article" @default.
• W2900390765 hasAuthorship W2900390765A5002054724 @default.
• W2900390765 hasAuthorship W2900390765A5013692065 @default.
• W2900390765 hasAuthorship W2900390765A5018324670 @default.
• W2900390765 hasAuthorship W2900390765A5022723256 @default.
• W2900390765 hasAuthorship W2900390765A5029060394 @default.
• W2900390765 hasAuthorship W2900390765A5030835880 @default.
• W2900390765 hasAuthorship W2900390765A5036123607 @default.
• W2900390765 hasAuthorship W2900390765A5042919376 @default.
• W2900390765 hasAuthorship W2900390765A5050622690 @default.
• W2900390765 hasAuthorship W2900390765A5063292856 @default.
• W2900390765 hasAuthorship W2900390765A5065006335 @default.
• W2900390765 hasAuthorship W2900390765A5065537915 @default.
• W2900390765 hasAuthorship W2900390765A5073887323 @default.

• next