FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2900522247> ?p ?o ?g. }

• W2900522247 abstract "Abstract The current definition of plasma cell leukemia (PCL)— ≥ 20% circulating plasma cells (CPCs) on peripheral smear and plasma cell count ≥ 2 × 10 9 /L—may be too stringent. We reviewed outcomes of 176 multiple myeloma (MM) patients diagnosed between 1971 and 2016, and who had CPCs detectable at diagnosis, to determine whether a lower threshold could be used to diagnose PCL. Median overall survival (mOS) was 1.1 years (95% CI 0.8–1.4) and was similar between patients with < 5% ( n = 54, mOS = 1.4 years [0.7–2.0]), 5–19% ( n = 63, mOS = 1.1 years [0.7–1.4]), and ≥ 20% CPCs ( n = 59, mOS = 1.1 years [0.7–1.5], p = 0.349). As survival was similar between those with 5–19% and ≥ 20% CPCs, we stratified patients by < 5% (mOS = 1.4 years [0.7–2.0]) and ≥ 5% CPCs (mOS = 1.1 years [0.8–1.4], p = 0.154). Outcomes of those with ≥ 5% CPCs were much poorer when compared with a cohort of MM patients diagnosed between 1971 and 2016, who did not have CPCs at diagnosis ( n = 9724, mOS = 4.4 yrs [4.3–4.5], p < 0.001); survival was also lower in patients diagnosed after 2001 with ≥ 5% CPCs ( n = 62, mOS = 1.4 years [0.8–2.5]) compared with patients with standard risk ( n = 1326, mOS = 7.5 years [7.0–8.7]) and high-risk MM ( n = 381, mOS = 4.3 years [3.5–4.9], p < 0.001). We therefore propose that the definition of PCL be revised to patients with ≥ 5% CPCs on peripheral blood smear, who otherwise meet diagnostic criteria for MM." @default.
• W2900522247 created "2018-11-29" @default.
• W2900522247 creator A5000308170 @default.
• W2900522247 creator A5007747233 @default.
• W2900522247 creator A5012403700 @default.
• W2900522247 creator A5012884078 @default.
• W2900522247 creator A5012985685 @default.
• W2900522247 creator A5016853434 @default.
• W2900522247 creator A5023193953 @default.
• W2900522247 creator A5026574827 @default.
• W2900522247 creator A5029802364 @default.
• W2900522247 creator A5033220547 @default.
• W2900522247 creator A5036150860 @default.
• W2900522247 creator A5036761306 @default.
• W2900522247 creator A5038546398 @default.
• W2900522247 creator A5042723532 @default.
• W2900522247 creator A5054957898 @default.
• W2900522247 creator A5068637846 @default.
• W2900522247 creator A5076611748 @default.
• W2900522247 creator A5090694142 @default.
• W2900522247 date "2018-11-15" @default.
• W2900522247 modified "2023-10-13" @default.
• W2900522247 title "Revised diagnostic criteria for plasma cell leukemia: results of a Mayo Clinic study with comparison of outcomes to multiple myeloma" @default.
• W2900522247 cites W2002324468 @default.
• W2900522247 cites W2003426156 @default.
• W2900522247 cites W2023779399 @default.
• W2900522247 cites W2029070213 @default.
• W2900522247 cites W2053056464 @default.
• W2900522247 cites W2060957671 @default.
• W2900522247 cites W2070653024 @default.
• W2900522247 cites W2071815761 @default.
• W2900522247 cites W2082169216 @default.
• W2900522247 cites W2095561966 @default.
• W2900522247 cites W2592709014 @default.
• W2900522247 cites W2620196988 @default.
• W2900522247 doi "https://doi.org/10.1038/s41408-018-0140-1" @default.
• W2900522247 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6238010" @default.
• W2900522247 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30442928" @default.
• W2900522247 hasPublicationYear "2018" @default.
• W2900522247 type Work @default.
• W2900522247 sameAs 2900522247 @default.
• W2900522247 citedByCount "57" @default.
• W2900522247 countsByYear W29005222472019 @default.
• W2900522247 countsByYear W29005222472020 @default.
• W2900522247 countsByYear W29005222472021 @default.
• W2900522247 countsByYear W29005222472022 @default.
• W2900522247 countsByYear W29005222472023 @default.
• W2900522247 crossrefType "journal-article" @default.
• W2900522247 hasAuthorship W2900522247A5000308170 @default.
• W2900522247 hasAuthorship W2900522247A5007747233 @default.
• W2900522247 hasAuthorship W2900522247A5012403700 @default.
• W2900522247 hasAuthorship W2900522247A5012884078 @default.
• W2900522247 hasAuthorship W2900522247A5012985685 @default.
• W2900522247 hasAuthorship W2900522247A5016853434 @default.
• W2900522247 hasAuthorship W2900522247A5023193953 @default.
• W2900522247 hasAuthorship W2900522247A5026574827 @default.
• W2900522247 hasAuthorship W2900522247A5029802364 @default.
• W2900522247 hasAuthorship W2900522247A5033220547 @default.
• W2900522247 hasAuthorship W2900522247A5036150860 @default.
• W2900522247 hasAuthorship W2900522247A5036761306 @default.
• W2900522247 hasAuthorship W2900522247A5038546398 @default.
• W2900522247 hasAuthorship W2900522247A5042723532 @default.
• W2900522247 hasAuthorship W2900522247A5054957898 @default.
• W2900522247 hasAuthorship W2900522247A5068637846 @default.
• W2900522247 hasAuthorship W2900522247A5076611748 @default.
• W2900522247 hasAuthorship W2900522247A5090694142 @default.
• W2900522247 hasBestOaLocation W29005222471 @default.
• W2900522247 hasConcept C126322002 @default.
• W2900522247 hasConcept C2776364478 @default.
• W2900522247 hasConcept C2778461978 @default.
• W2900522247 hasConcept C2780353925 @default.
• W2900522247 hasConcept C71924100 @default.
• W2900522247 hasConcept C72563966 @default.
• W2900522247 hasConcept C90924648 @default.
• W2900522247 hasConceptScore W2900522247C126322002 @default.
• W2900522247 hasConceptScore W2900522247C2776364478 @default.
• W2900522247 hasConceptScore W2900522247C2778461978 @default.
• W2900522247 hasConceptScore W2900522247C2780353925 @default.
• W2900522247 hasConceptScore W2900522247C71924100 @default.
• W2900522247 hasConceptScore W2900522247C72563966 @default.
• W2900522247 hasConceptScore W2900522247C90924648 @default.
• W2900522247 hasIssue "12" @default.
• W2900522247 hasLocation W29005222471 @default.
• W2900522247 hasLocation W29005222472 @default.
• W2900522247 hasLocation W29005222473 @default.
• W2900522247 hasLocation W29005222474 @default.
• W2900522247 hasOpenAccess W2900522247 @default.
• W2900522247 hasPrimaryLocation W29005222471 @default.
• W2900522247 hasRelatedWork W205719917 @default.
• W2900522247 hasRelatedWork W2099429225 @default.
• W2900522247 hasRelatedWork W2101761743 @default.
• W2900522247 hasRelatedWork W23652200 @default.
• W2900522247 hasRelatedWork W2398923138 @default.
• W2900522247 hasRelatedWork W2407675164 @default.
• W2900522247 hasRelatedWork W2416335865 @default.
• W2900522247 hasRelatedWork W3134462279 @default.
• W2900522247 hasRelatedWork W4290366598 @default.
• W2900522247 hasRelatedWork W3117678683 @default.
• W2900522247 hasVolume "8" @default.
• W2900522247 isParatext "false" @default.

• next