FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2900538105> ?p ?o ?g. }

• W2900538105 endingPage "2562" @default.
• W2900538105 startingPage "2551" @default.
• W2900538105 abstract "The GUIDE-IT (GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure) trial prospectively compared the efficacy of an N-terminal pro–B-type natriuretic peptide (NT-proBNP)–guided heart failure treatment strategy (target NT-proBNP level <1,000 pg/ml) with optimal medical therapy alone in high-risk patients with heart failure and reduced ejection fraction. When the study was stopped for futility, 894 patients had been enrolled. The purpose of this study was to assess treatment-related quality-of-life (QOL) and economic outcomes in the GUIDE-IT trial. The authors prospectively collected a battery of QOL instruments at baseline and 3, 6, 12, and 24 months post-randomization (collection rates 90% to 99% of those eligible). The principal pre-specified QOL measures were the Kansas City Cardiomyopathy Questionnaire (KCCQ) Overall Summary Score and the Duke Activity Status Index (DASI). Cost data were collected for 735 (97%) U.S. patients. Baseline variables were well balanced in the 446 patients randomized to the NT-proBNP–guided therapy and 448 to usual care. Both the KCCQ and the DASI improved over the first 6 months, but no evidence was found for a strategy-related difference (mean difference [biomarker-guided − usual care] at 24 months of follow-up 2.0 for DASI [95% confidence interval (CI): −1.3 to 5.3] and 1.1 for KCCQ [95% CI: −3.7 to 5.9]). Total winsorized costs averaged $5,919 higher in the biomarker-guided strategy (95% CI: −$1,795, +$13,602) over 15-month median follow-up. A strategy of NT-proBNP–guided HF therapy had higher total costs and was not more effective than usual care in improving QOL outcomes in patients with heart failure and a reduced ejection fraction. (Guiding Evidence Based Therapy Using Biomarker Intensified Treatment [GUIDE-IT]; NCT01685840 )" @default.
• W2900538105 created "2018-11-29" @default.
• W2900538105 creator A5000229386 @default.
• W2900538105 creator A5006527198 @default.
• W2900538105 creator A5008998799 @default.
• W2900538105 creator A5011582286 @default.
• W2900538105 creator A5015595507 @default.
• W2900538105 creator A5022076272 @default.
• W2900538105 creator A5023757786 @default.
• W2900538105 creator A5032690649 @default.
• W2900538105 creator A5043064522 @default.
• W2900538105 creator A5043416120 @default.
• W2900538105 creator A5047824356 @default.
• W2900538105 creator A5058444528 @default.
• W2900538105 creator A5063918424 @default.
• W2900538105 creator A5069065466 @default.
• W2900538105 creator A5071968251 @default.
• W2900538105 creator A5081335385 @default.
• W2900538105 creator A5090349245 @default.
• W2900538105 date "2018-11-01" @default.
• W2900538105 modified "2023-10-09" @default.
• W2900538105 title "Economic and Quality-of-Life Outcomes of Natriuretic Peptide–Guided Therapy for Heart Failure" @default.
• W2900538105 cites W1900290642 @default.
• W2900538105 cites W2020688767 @default.
• W2900538105 cites W2044591445 @default.
• W2900538105 cites W2056914680 @default.
• W2900538105 cites W2064279221 @default.
• W2900538105 cites W2066228805 @default.
• W2900538105 cites W2083650930 @default.
• W2900538105 cites W2112778345 @default.
• W2900538105 cites W2151562223 @default.
• W2900538105 cites W2167591863 @default.
• W2900538105 cites W2274990799 @default.
• W2900538105 cites W2324745151 @default.
• W2900538105 cites W2394904275 @default.
• W2900538105 cites W2473786944 @default.
• W2900538105 cites W2588590290 @default.
• W2900538105 cites W2599933528 @default.
• W2900538105 cites W2745438221 @default.
• W2900538105 doi "https://doi.org/10.1016/j.jacc.2018.08.2184" @default.
• W2900538105 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6261478" @default.
• W2900538105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30466512" @default.
• W2900538105 hasPublicationYear "2018" @default.
• W2900538105 type Work @default.
• W2900538105 sameAs 2900538105 @default.
• W2900538105 citedByCount "18" @default.
• W2900538105 countsByYear W29005381052018 @default.
• W2900538105 countsByYear W29005381052019 @default.
• W2900538105 countsByYear W29005381052020 @default.
• W2900538105 countsByYear W29005381052021 @default.
• W2900538105 countsByYear W29005381052022 @default.
• W2900538105 countsByYear W29005381052023 @default.
• W2900538105 crossrefType "journal-article" @default.
• W2900538105 hasAuthorship W2900538105A5000229386 @default.
• W2900538105 hasAuthorship W2900538105A5006527198 @default.
• W2900538105 hasAuthorship W2900538105A5008998799 @default.
• W2900538105 hasAuthorship W2900538105A5011582286 @default.
• W2900538105 hasAuthorship W2900538105A5015595507 @default.
• W2900538105 hasAuthorship W2900538105A5022076272 @default.
• W2900538105 hasAuthorship W2900538105A5023757786 @default.
• W2900538105 hasAuthorship W2900538105A5032690649 @default.
• W2900538105 hasAuthorship W2900538105A5043064522 @default.
• W2900538105 hasAuthorship W2900538105A5043416120 @default.
• W2900538105 hasAuthorship W2900538105A5047824356 @default.
• W2900538105 hasAuthorship W2900538105A5058444528 @default.
• W2900538105 hasAuthorship W2900538105A5063918424 @default.
• W2900538105 hasAuthorship W2900538105A5069065466 @default.
• W2900538105 hasAuthorship W2900538105A5071968251 @default.
• W2900538105 hasAuthorship W2900538105A5081335385 @default.
• W2900538105 hasAuthorship W2900538105A5090349245 @default.
• W2900538105 hasBestOaLocation W29005381051 @default.
• W2900538105 hasConcept C111472728 @default.
• W2900538105 hasConcept C126322002 @default.
• W2900538105 hasConcept C138885662 @default.
• W2900538105 hasConcept C159110408 @default.
• W2900538105 hasConcept C164705383 @default.
• W2900538105 hasConcept C177713679 @default.
• W2900538105 hasConcept C2775846464 @default.
• W2900538105 hasConcept C2775915353 @default.
• W2900538105 hasConcept C2778198053 @default.
• W2900538105 hasConcept C2779530757 @default.
• W2900538105 hasConcept C2779951463 @default.
• W2900538105 hasConcept C71924100 @default.
• W2900538105 hasConceptScore W2900538105C111472728 @default.
• W2900538105 hasConceptScore W2900538105C126322002 @default.
• W2900538105 hasConceptScore W2900538105C138885662 @default.
• W2900538105 hasConceptScore W2900538105C159110408 @default.
• W2900538105 hasConceptScore W2900538105C164705383 @default.
• W2900538105 hasConceptScore W2900538105C177713679 @default.
• W2900538105 hasConceptScore W2900538105C2775846464 @default.
• W2900538105 hasConceptScore W2900538105C2775915353 @default.
• W2900538105 hasConceptScore W2900538105C2778198053 @default.
• W2900538105 hasConceptScore W2900538105C2779530757 @default.
• W2900538105 hasConceptScore W2900538105C2779951463 @default.
• W2900538105 hasConceptScore W2900538105C71924100 @default.
• W2900538105 hasIssue "21" @default.
• W2900538105 hasLocation W29005381051 @default.
• W2900538105 hasLocation W29005381052 @default.

• next