Matches in SemOpenAlex for { <https://semopenalex.org/work/W2900543622> ?p ?o ?g. }
- W2900543622 abstract "In striking analogy with Saccharomyces cerevisiae, etiolated pea stem mitochondria did not show appreciable Ca2+ uptake. Only treatment with the ionophore ETH129 (which allows electrophoretic Ca2+ equilibration) caused Ca2+ uptake followed by increased inner membrane permeability, membrane depolarization and Ca2+ release. Like the permeability transition (PT) of mammals, yeast and Drosophila, the PT of pea stem mitochondria was stimulated by diamide and phenylarsine oxide and inhibited by Mg-ADP and Mg-ATP, suggesting a common underlying mechanism; yet, the plant PT also displayed distinctive features: (i) as in mammals it was desensitized by cyclosporin A, which does not affect the PT of yeast and Drosophila; (ii) similarly to S. cerevisiae and Drosophila it was inhibited by Pi, which stimulates the PT of mammals; (iii) like in mammals and Drosophila it was sensitized by benzodiazepine 423, which is ineffective in S. cerevisiae; (iv) like what observed in Drosophila it did not mediate swelling and cytochrome c release, which is instead seen in mammals and S. cerevisiae. We find that cyclophilin D, the mitochondrial receptor for cyclosporin A, is present in pea stem mitochondria. These results indicate that the plant PT has unique features and suggest that, as in Drosophila, it may provide pea stem mitochondria with a Ca2+ release channel." @default.
- W2900543622 created "2018-11-29" @default.
- W2900543622 creator A5003811230 @default.
- W2900543622 creator A5009191571 @default.
- W2900543622 creator A5013135864 @default.
- W2900543622 creator A5024013443 @default.
- W2900543622 creator A5025642171 @default.
- W2900543622 creator A5037545121 @default.
- W2900543622 creator A5047963189 @default.
- W2900543622 creator A5064932458 @default.
- W2900543622 creator A5069742020 @default.
- W2900543622 creator A5079461218 @default.
- W2900543622 creator A5081275283 @default.
- W2900543622 creator A5082981110 @default.
- W2900543622 creator A5086887394 @default.
- W2900543622 creator A5087423409 @default.
- W2900543622 date "2018-11-21" @default.
- W2900543622 modified "2023-09-29" @default.
- W2900543622 title "Properties of the Permeability Transition of Pea Stem Mitochondria" @default.
- W2900543622 cites W117168218 @default.
- W2900543622 cites W1250509468 @default.
- W2900543622 cites W1480051253 @default.
- W2900543622 cites W1492823505 @default.
- W2900543622 cites W1500536335 @default.
- W2900543622 cites W150246076 @default.
- W2900543622 cites W1507410890 @default.
- W2900543622 cites W1520029337 @default.
- W2900543622 cites W1567313097 @default.
- W2900543622 cites W1603109630 @default.
- W2900543622 cites W1895235630 @default.
- W2900543622 cites W1916782710 @default.
- W2900543622 cites W1928796416 @default.
- W2900543622 cites W1963771127 @default.
- W2900543622 cites W1964126982 @default.
- W2900543622 cites W1968273273 @default.
- W2900543622 cites W1972262318 @default.
- W2900543622 cites W1980349602 @default.
- W2900543622 cites W1986085714 @default.
- W2900543622 cites W1987952787 @default.
- W2900543622 cites W1989014446 @default.
- W2900543622 cites W1992417877 @default.
- W2900543622 cites W1993418135 @default.
- W2900543622 cites W1994442108 @default.
- W2900543622 cites W1995278643 @default.
- W2900543622 cites W2001756549 @default.
- W2900543622 cites W2003626070 @default.
- W2900543622 cites W2007071144 @default.
- W2900543622 cites W2008875935 @default.
- W2900543622 cites W2009370765 @default.
- W2900543622 cites W2015606024 @default.
- W2900543622 cites W2022211348 @default.
- W2900543622 cites W2023462237 @default.
- W2900543622 cites W2028900979 @default.
- W2900543622 cites W2030618370 @default.
- W2900543622 cites W2034987188 @default.
- W2900543622 cites W2036302841 @default.
- W2900543622 cites W2039444414 @default.
- W2900543622 cites W2043135080 @default.
- W2900543622 cites W2043704060 @default.
- W2900543622 cites W2048875504 @default.
- W2900543622 cites W2050811403 @default.
- W2900543622 cites W2052737683 @default.
- W2900543622 cites W2054047617 @default.
- W2900543622 cites W2055182041 @default.
- W2900543622 cites W2055886495 @default.
- W2900543622 cites W2057257618 @default.
- W2900543622 cites W2060629451 @default.
- W2900543622 cites W2066200217 @default.
- W2900543622 cites W2068119233 @default.
- W2900543622 cites W2068619217 @default.
- W2900543622 cites W2074330066 @default.
- W2900543622 cites W2075199390 @default.
- W2900543622 cites W2078052761 @default.
- W2900543622 cites W2081541107 @default.
- W2900543622 cites W2087452217 @default.
- W2900543622 cites W2091666277 @default.
- W2900543622 cites W2092514471 @default.
- W2900543622 cites W2094547290 @default.
- W2900543622 cites W2097606533 @default.
- W2900543622 cites W2099724934 @default.
- W2900543622 cites W210075245 @default.
- W2900543622 cites W2106533942 @default.
- W2900543622 cites W2111173560 @default.
- W2900543622 cites W2116444561 @default.
- W2900543622 cites W2117934084 @default.
- W2900543622 cites W2121818600 @default.
- W2900543622 cites W2124389936 @default.
- W2900543622 cites W2124767565 @default.
- W2900543622 cites W2128635872 @default.
- W2900543622 cites W2129132156 @default.
- W2900543622 cites W2129621365 @default.
- W2900543622 cites W2131287138 @default.
- W2900543622 cites W2140151986 @default.
- W2900543622 cites W2142579693 @default.
- W2900543622 cites W2143159230 @default.
- W2900543622 cites W2169604089 @default.
- W2900543622 cites W2202366653 @default.
- W2900543622 cites W2208134715 @default.
- W2900543622 cites W2235622324 @default.
- W2900543622 cites W2258689029 @default.