FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2900769622> ?p ?o ?g. }

• W2900769622 endingPage "543" @default.
• W2900769622 startingPage "536" @default.
• W2900769622 abstract "Increasing reports of successful and safe application of bone marrow derived mesenchymal stem cells (BM-MSCs) for cell therapy are pouring in from numerous studies. However poor survival of transplanted cells in the recipient has impaired the benefits of BM-MSCs based therapies. Therefore cell product preparation procedures pertaining to MSC therapy need to be optimized to improve the survival of transplanted cells. One of the important ex vivo procedures in the preparation of cells for therapy is passaging of BM-MSCs to ensure a suitable number of cells for transplantation, which may affect the turnover of proteins involved in regulation of cell survival and (or) death pathways. In the current study, we investigated the effect of an increase in passage number of BM-MSCs in cell culture on the intracellular protein turnover (protein synthesis, processing, and degradation machinery). We performed proteomic analysis of BM-MSCs at different passages. There was no significant difference observed in the ribosomal, protein processing, and proteasomal pathways related proteins in BM-MSCs with an increase in passage number from P3 to P7. Therefore, expansion of MSCs in the cell culture in clinically relevant passages (Passage 3–7) does not affect the quality of MSCs in terms of intracellular protein synthesis and turnover." @default.
• W2900769622 created "2018-11-29" @default.
• W2900769622 creator A5021449843 @default.
• W2900769622 creator A5023036822 @default.
• W2900769622 creator A5045297090 @default.
• W2900769622 creator A5053279844 @default.
• W2900769622 creator A5073826158 @default.
• W2900769622 creator A5074717983 @default.
• W2900769622 creator A5086474562 @default.
• W2900769622 date "2019-06-01" @default.
• W2900769622 modified "2023-10-16" @default.
• W2900769622 title "High throughput screening reveals no significant changes in protein synthesis, processing, and degradation machinery during passaging of mesenchymal stem cells" @default.
• W2900769622 cites W1910742191 @default.
• W2900769622 cites W1968628080 @default.
• W2900769622 cites W1986224715 @default.
• W2900769622 cites W2031790029 @default.
• W2900769622 cites W2033696318 @default.
• W2900769622 cites W2058238065 @default.
• W2900769622 cites W2083860653 @default.
• W2900769622 cites W2087092058 @default.
• W2900769622 cites W2103644580 @default.
• W2900769622 cites W2127722636 @default.
• W2900769622 cites W2139837621 @default.
• W2900769622 cites W2143976934 @default.
• W2900769622 cites W2150874460 @default.
• W2900769622 cites W2163263636 @default.
• W2900769622 cites W2182766838 @default.
• W2900769622 cites W2221267861 @default.
• W2900769622 cites W2438500403 @default.
• W2900769622 cites W2620738021 @default.
• W2900769622 cites W2757074440 @default.
• W2900769622 cites W2766889331 @default.
• W2900769622 cites W2781940317 @default.
• W2900769622 cites W2801108382 @default.
• W2900769622 cites W2801946181 @default.
• W2900769622 cites W2805892376 @default.
• W2900769622 cites W2808550614 @default.
• W2900769622 doi "https://doi.org/10.1139/cjpp-2018-0553" @default.
• W2900769622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30422687" @default.
• W2900769622 hasPublicationYear "2019" @default.
• W2900769622 type Work @default.
• W2900769622 sameAs 2900769622 @default.
• W2900769622 citedByCount "5" @default.
• W2900769622 countsByYear W29007696222019 @default.
• W2900769622 countsByYear W29007696222020 @default.
• W2900769622 countsByYear W29007696222022 @default.
• W2900769622 crossrefType "journal-article" @default.
• W2900769622 hasAuthorship W2900769622A5021449843 @default.
• W2900769622 hasAuthorship W2900769622A5023036822 @default.
• W2900769622 hasAuthorship W2900769622A5045297090 @default.
• W2900769622 hasAuthorship W2900769622A5053279844 @default.
• W2900769622 hasAuthorship W2900769622A5073826158 @default.
• W2900769622 hasAuthorship W2900769622A5074717983 @default.
• W2900769622 hasAuthorship W2900769622A5086474562 @default.
• W2900769622 hasConcept C10882517 @default.
• W2900769622 hasConcept C126322002 @default.
• W2900769622 hasConcept C1491633281 @default.
• W2900769622 hasConcept C153911025 @default.
• W2900769622 hasConcept C195580219 @default.
• W2900769622 hasConcept C198826908 @default.
• W2900769622 hasConcept C203014093 @default.
• W2900769622 hasConcept C2780007613 @default.
• W2900769622 hasConcept C28328180 @default.
• W2900769622 hasConcept C2911091166 @default.
• W2900769622 hasConcept C2992195973 @default.
• W2900769622 hasConcept C3675279 @default.
• W2900769622 hasConcept C54355233 @default.
• W2900769622 hasConcept C55493867 @default.
• W2900769622 hasConcept C71924100 @default.
• W2900769622 hasConcept C79879829 @default.
• W2900769622 hasConcept C81885089 @default.
• W2900769622 hasConcept C86803240 @default.
• W2900769622 hasConcept C95444343 @default.
• W2900769622 hasConceptScore W2900769622C10882517 @default.
• W2900769622 hasConceptScore W2900769622C126322002 @default.
• W2900769622 hasConceptScore W2900769622C1491633281 @default.
• W2900769622 hasConceptScore W2900769622C153911025 @default.
• W2900769622 hasConceptScore W2900769622C195580219 @default.
• W2900769622 hasConceptScore W2900769622C198826908 @default.
• W2900769622 hasConceptScore W2900769622C203014093 @default.
• W2900769622 hasConceptScore W2900769622C2780007613 @default.
• W2900769622 hasConceptScore W2900769622C28328180 @default.
• W2900769622 hasConceptScore W2900769622C2911091166 @default.
• W2900769622 hasConceptScore W2900769622C2992195973 @default.
• W2900769622 hasConceptScore W2900769622C3675279 @default.
• W2900769622 hasConceptScore W2900769622C54355233 @default.
• W2900769622 hasConceptScore W2900769622C55493867 @default.
• W2900769622 hasConceptScore W2900769622C71924100 @default.
• W2900769622 hasConceptScore W2900769622C79879829 @default.
• W2900769622 hasConceptScore W2900769622C81885089 @default.
• W2900769622 hasConceptScore W2900769622C86803240 @default.
• W2900769622 hasConceptScore W2900769622C95444343 @default.
• W2900769622 hasIssue "6" @default.
• W2900769622 hasLocation W29007696221 @default.
• W2900769622 hasLocation W29007696222 @default.
• W2900769622 hasOpenAccess W2900769622 @default.
• W2900769622 hasPrimaryLocation W29007696221 @default.
• W2900769622 hasRelatedWork W2030789584 @default.

• next