Matches in SemOpenAlex for { <https://semopenalex.org/work/W2901072585> ?p ?o ?g. }
- W2901072585 endingPage "79" @default.
- W2901072585 startingPage "70" @default.
- W2901072585 abstract "Abstract Nanotechnology has been extensively explored for the potential applications in developing materials for sustained drug release. In this study, a modified coaxial electrospinning, characterized by a detachable concentric spinneret, was developed for the fabrication of a new kind of hybrid structural nanomaterials. The hybrid nanofibers consisted of a drug-free thin layer of glycerol monostearate as the shell and a drug-loaded nanocomposite containing berberine hydrochloride and ethylcellulose as the core, which were confirmed by scanning electron microscopic and transmission electron microscopic results. X-ray diffraction analyses suggested that the drug berberine hydrochloride was converted into an amorphous state with the carrier ethylcellulose in the core section. Fourier transform infrared spectra suggested that all the components were compatible. In vitro dissolution tests verified that the structural hybrids can provide an improved drug sustained-release profile than monolithic medicated nanocomposites in terms of initial burst release, sustained-release time and tailing-off time. The mechanism involving the influences of sheath layer on the drug release behaviour was suggested. The reported protocols pave a new way for fabricating lipid–polymer-based functional nanostructures with accurate structure–property–performance relationship and are useful for developing a series of new functional nanomaterials." @default.
- W2901072585 created "2018-11-29" @default.
- W2901072585 creator A5015681225 @default.
- W2901072585 creator A5026906414 @default.
- W2901072585 creator A5032500874 @default.
- W2901072585 creator A5038888536 @default.
- W2901072585 creator A5070104773 @default.
- W2901072585 creator A5085574353 @default.
- W2901072585 date "2019-01-01" @default.
- W2901072585 modified "2023-10-15" @default.
- W2901072585 title "Electrospun lipid-coated medicated nanocomposites for an improved drug sustained-release profile" @default.
- W2901072585 cites W1839895561 @default.
- W2901072585 cites W1966163938 @default.
- W2901072585 cites W1994584281 @default.
- W2901072585 cites W2005690644 @default.
- W2901072585 cites W2010976109 @default.
- W2901072585 cites W2016599223 @default.
- W2901072585 cites W2020042779 @default.
- W2901072585 cites W2061275221 @default.
- W2901072585 cites W2070803838 @default.
- W2901072585 cites W2075199222 @default.
- W2901072585 cites W2088978238 @default.
- W2901072585 cites W2114174768 @default.
- W2901072585 cites W2131566852 @default.
- W2901072585 cites W2137925796 @default.
- W2901072585 cites W2139042900 @default.
- W2901072585 cites W2158272832 @default.
- W2901072585 cites W2191384512 @default.
- W2901072585 cites W2212821214 @default.
- W2901072585 cites W2220286109 @default.
- W2901072585 cites W2296629312 @default.
- W2901072585 cites W2340437214 @default.
- W2901072585 cites W2344598639 @default.
- W2901072585 cites W2367982160 @default.
- W2901072585 cites W2517056110 @default.
- W2901072585 cites W2525379390 @default.
- W2901072585 cites W2556421773 @default.
- W2901072585 cites W2560818504 @default.
- W2901072585 cites W2568308373 @default.
- W2901072585 cites W2582545255 @default.
- W2901072585 cites W2588785586 @default.
- W2901072585 cites W2606359044 @default.
- W2901072585 cites W2609225225 @default.
- W2901072585 cites W2614857817 @default.
- W2901072585 cites W2722312560 @default.
- W2901072585 cites W2748417965 @default.
- W2901072585 cites W2748709776 @default.
- W2901072585 cites W2757232396 @default.
- W2901072585 cites W2760716224 @default.
- W2901072585 cites W2762243259 @default.
- W2901072585 cites W2766475873 @default.
- W2901072585 cites W2767566055 @default.
- W2901072585 cites W2774455919 @default.
- W2901072585 cites W2776920687 @default.
- W2901072585 cites W2777457987 @default.
- W2901072585 cites W2777557500 @default.
- W2901072585 cites W2789630325 @default.
- W2901072585 cites W2790096814 @default.
- W2901072585 cites W2795918445 @default.
- W2901072585 cites W2803851520 @default.
- W2901072585 cites W2805904181 @default.
- W2901072585 cites W2810482708 @default.
- W2901072585 cites W2811347705 @default.
- W2901072585 cites W2883244229 @default.
- W2901072585 cites W2887170803 @default.
- W2901072585 cites W2888881657 @default.
- W2901072585 cites W2890004751 @default.
- W2901072585 cites W2891870419 @default.
- W2901072585 cites W2893674017 @default.
- W2901072585 doi "https://doi.org/10.1016/j.matdes.2018.11.036" @default.
- W2901072585 hasPublicationYear "2019" @default.
- W2901072585 type Work @default.
- W2901072585 sameAs 2901072585 @default.
- W2901072585 citedByCount "87" @default.
- W2901072585 countsByYear W29010725852018 @default.
- W2901072585 countsByYear W29010725852019 @default.
- W2901072585 countsByYear W29010725852020 @default.
- W2901072585 countsByYear W29010725852021 @default.
- W2901072585 countsByYear W29010725852022 @default.
- W2901072585 countsByYear W29010725852023 @default.
- W2901072585 crossrefType "journal-article" @default.
- W2901072585 hasAuthorship W2901072585A5015681225 @default.
- W2901072585 hasAuthorship W2901072585A5026906414 @default.
- W2901072585 hasAuthorship W2901072585A5032500874 @default.
- W2901072585 hasAuthorship W2901072585A5038888536 @default.
- W2901072585 hasAuthorship W2901072585A5070104773 @default.
- W2901072585 hasAuthorship W2901072585A5085574353 @default.
- W2901072585 hasBestOaLocation W29010725851 @default.
- W2901072585 hasConcept C136229726 @default.
- W2901072585 hasConcept C159985019 @default.
- W2901072585 hasConcept C171250308 @default.
- W2901072585 hasConcept C192562407 @default.
- W2901072585 hasConcept C2780035454 @default.
- W2901072585 hasConcept C71924100 @default.
- W2901072585 hasConcept C92880739 @default.
- W2901072585 hasConcept C98274493 @default.
- W2901072585 hasConceptScore W2901072585C136229726 @default.
- W2901072585 hasConceptScore W2901072585C159985019 @default.