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- W2901091544 endingPage "7" @default.
- W2901091544 startingPage "7" @default.
- W2901091544 abstract "Rats have been the primary model to study the process and underlying mechanisms of recovery after spinal cord injury. Two weeks after a severe spinal cord contusion, rats can regain weight-bearing abilities without therapeutic interventions, as assessed by the Basso, Beattie and Bresnahan locomotor scale. However, many human patients suffer from permanent loss of motor function following spinal cord injury. While rats are the most understood animal model, major differences in sensorimotor pathways between quadrupeds and bipeds need to be considered. Understanding the major differences between the sensorimotor pathways of rats, non-human primates, and humans is a start to improving targets for treatments of human spinal cord injury. This review will discuss the neuroplasticity of the brain and spinal cord after spinal cord injury in rats, non-human primates, and humans. A brief overview of emerging interventions to induce plasticity in humans with spinal cord injury will also be discussed." @default.
- W2901091544 created "2018-11-29" @default.
- W2901091544 creator A5000622434 @default.
- W2901091544 creator A5001234047 @default.
- W2901091544 creator A5020366061 @default.
- W2901091544 creator A5043888247 @default.
- W2901091544 creator A5056010127 @default.
- W2901091544 creator A5066031091 @default.
- W2901091544 creator A5086660764 @default.
- W2901091544 creator A5087201541 @default.
- W2901091544 date "2019-01-01" @default.
- W2901091544 modified "2023-10-18" @default.
- W2901091544 title "Differences in neuroplasticity after spinal cord injury in varying animal models and humans" @default.
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