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- W2901131281 abstract "With rare exceptions, lesions of the glomus jugulare are benign, slow-growing paragangliomas. Advances in neuroimaging, skull base techniques, embolization, and anesthetic agents, along with emphasis on postoperative care have markedly improved the surgeons’ ability to remove these tumors and have improved outcome in an overwhelming number of patients who present with tumors of the glomus jugulare. Studies that include long-term follow up show the effectiveness of total removal in achieving a cure. There remains, however, a rare subgroup of glomus jugulare tumors that continue to present a formidable challenge to treatment. We have used the term “complex glomus jugulare tumors” to classify this group. These tumors are frequently considered to be extremely high risk or inoperable. One or more of the following criteria should be met to qualify a case for this designation: giant size, multiple paragangliomas (bilateral or ipsilateral), malignancy, catecholamine secretion, or association with other lesions such as dural arteriovenous malformations or an adrenal tumor. Previous treatment that resulted in adverse outcomes such as sacrifice of the carotid artery, necessity for radiation therapy, postoperative deficit, or adverse effect from embolization makes surgical intervention much more risky. We undertook the management of these tumors and report on the challenges involved in surgical removal, with commentary on various techniques and their outcomes. We emphasize the perioperative management of these lesions in special situations such as hypersecretion, multiple paragangliomas, and vascular involvement, and we discuss the rare malignant behavior of some of these tumors." @default.
- W2901131281 created "2018-11-29" @default.
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- W2901131281 date "2004-08-01" @default.
- W2901131281 modified "2023-10-09" @default.
- W2901131281 title "Commentary: Complex tumors of the glomus jugulare: criteria, treatment, and outcome." @default.
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- W2901131281 doi "https://doi.org/10.3171/foc.2004.17.2.13" @default.
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