Matches in SemOpenAlex for { <https://semopenalex.org/work/W2901293857> ?p ?o ?g. }
- W2901293857 endingPage "33" @default.
- W2901293857 startingPage "33" @default.
- W2901293857 abstract "Senescence is a stable cell cycle arrest that is either tumor suppressive or tumor promoting depending on context. Epigenetic changes such as histone methylation are known to affect both the induction and suppression of senescence by altering expression of genes that regulate the cell cycle and the senescence-associated secretory phenotype. A conserved group of proteins containing a Jumonji C (JmjC) domain alter chromatin state, and therefore gene expression, by demethylating histones. Here, we will discuss what is currently known about JmjC demethylases in the induction of senescence, and how these enzymes suppress senescence to contribute to tumorigenesis." @default.
- W2901293857 created "2018-11-29" @default.
- W2901293857 creator A5006198831 @default.
- W2901293857 creator A5050786653 @default.
- W2901293857 date "2019-01-09" @default.
- W2901293857 modified "2023-09-27" @default.
- W2901293857 title "Jumonji C Demethylases in Cellular Senescence" @default.
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