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• W2901295625 startingPage "1585" @default.
• W2901295625 abstract "Aim: Trauma exposure is a necessary, but not deterministic, contributor to post-traumatic stress disorder (PTSD). Epigenetic factors may distinguish between trauma-exposed individuals with versus without PTSD. Materials & methods: We conducted a meta-analysis of PTSD epigenome-wide association studies in trauma-exposed cohorts drawn from civilian contexts. Whole blood-derived DNA methylation levels were analyzed in 545 study participants, drawn from the three civilian cohorts participating in the PTSD working group of the Psychiatric Genomics Consortium. Results: Two CpG sites significantly associated with current PTSD in NRG1 (cg23637605) and in HGS (cg19577098). Conclusion: PTSD is associated with differential methylation, measured in blood, within HGS and NRG1 across three civilian cohorts." @default.
• W2901295625 created "2018-11-29" @default.
• W2901295625 creator A5004876138 @default.
• W2901295625 creator A5010556254 @default.
• W2901295625 creator A5011309891 @default.
• W2901295625 creator A5013710256 @default.
• W2901295625 creator A5025127395 @default.
• W2901295625 creator A5026464787 @default.
• W2901295625 creator A5031482400 @default.
• W2901295625 creator A5046378243 @default.
• W2901295625 creator A5064052128 @default.
• W2901295625 creator A5066335093 @default.
• W2901295625 creator A5073581575 @default.
• W2901295625 creator A5083615322 @default.
• W2901295625 creator A5083660592 @default.
• W2901295625 date "2018-12-01" @default.
• W2901295625 modified "2023-10-04" @default.
• W2901295625 title "Epigenetic meta-analysis across three civilian cohorts identifies <i>NRG1</i> and <i>HGS</i> as blood-based biomarkers for post-traumatic stress disorder" @default.
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