Matches in SemOpenAlex for { <https://semopenalex.org/work/W2901312299> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2901312299 endingPage "16" @default.
- W2901312299 startingPage "10" @default.
- W2901312299 abstract "3-MCPD, a contaminant frequently detected in foodstuffs, has been reported to damage human kidneys and testes. Previous studies can be used to evaluate the risk to humans of exposure to excessive 3-MCPD for a short period. However, the effects of withdrawal after 3-MCPD exposure have rarely been studied. Adult male SD rats were orally administered 0, 36 and 72 mg 3-MCPD/kg b.w./day for 4 weeks, followed by a 7-week recovery period. 3-MCPD significantly reduced RBC, HGB and HCT levels, indicating a phenotype of anemia, which returned to normal after the recovery period. 3-MCPD induced dysfunction in the liver and kidneys, which were characterized by hepatomegaly and elevated serum ALT, TBIL levels, and nephromegaly and elevated serum urea, UA contents. These effects were also restored to normal after the recovery period. Although the abnormal levels of testosterone and progesterone returned to normal, 3-MCPD-induced atrophy in testes, decreased sperm concentration and motility, and an increased rate of teratosperm still existed after the recovery period. 3-MCPD can induce restorable anemia and dysfunction in liver and kidney but irreversibly damage the reproductive system with normal sex hormone levels. This study may provide a novel perspective for characterizing the ongoing risk of exposure to 3-MCPD." @default.
- W2901312299 created "2018-11-29" @default.
- W2901312299 creator A5000403595 @default.
- W2901312299 creator A5004740687 @default.
- W2901312299 creator A5053863947 @default.
- W2901312299 creator A5070473172 @default.
- W2901312299 date "2019-02-01" @default.
- W2901312299 modified "2023-10-16" @default.
- W2901312299 title "3-Monochloropropane-1, 2-diol causes irreversible damage to reproductive ability independent of hormone changes in adult male rats" @default.
- W2901312299 cites W1465413975 @default.
- W2901312299 cites W1484856776 @default.
- W2901312299 cites W1976162006 @default.
- W2901312299 cites W1978315099 @default.
- W2901312299 cites W1980251140 @default.
- W2901312299 cites W1981905015 @default.
- W2901312299 cites W1994953267 @default.
- W2901312299 cites W1996016930 @default.
- W2901312299 cites W2015301355 @default.
- W2901312299 cites W2025975633 @default.
- W2901312299 cites W2026684616 @default.
- W2901312299 cites W2034769472 @default.
- W2901312299 cites W2047138715 @default.
- W2901312299 cites W2048491862 @default.
- W2901312299 cites W2052865131 @default.
- W2901312299 cites W2054227830 @default.
- W2901312299 cites W2056879103 @default.
- W2901312299 cites W2066389998 @default.
- W2901312299 cites W2071227754 @default.
- W2901312299 cites W2071518670 @default.
- W2901312299 cites W2072982730 @default.
- W2901312299 cites W2073795395 @default.
- W2901312299 cites W2077251269 @default.
- W2901312299 cites W2085994524 @default.
- W2901312299 cites W2096945589 @default.
- W2901312299 cites W2100853134 @default.
- W2901312299 cites W2112949705 @default.
- W2901312299 cites W2113674237 @default.
- W2901312299 cites W2132988768 @default.
- W2901312299 cites W2138369469 @default.
- W2901312299 cites W2326160013 @default.
- W2901312299 cites W2513957909 @default.
- W2901312299 cites W2900904264 @default.
- W2901312299 doi "https://doi.org/10.1016/j.fct.2018.11.023" @default.
- W2901312299 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30453003" @default.
- W2901312299 hasPublicationYear "2019" @default.
- W2901312299 type Work @default.
- W2901312299 sameAs 2901312299 @default.
- W2901312299 citedByCount "9" @default.
- W2901312299 countsByYear W29013122992021 @default.
- W2901312299 countsByYear W29013122992022 @default.
- W2901312299 countsByYear W29013122992023 @default.
- W2901312299 crossrefType "journal-article" @default.
- W2901312299 hasAuthorship W2901312299A5000403595 @default.
- W2901312299 hasAuthorship W2901312299A5004740687 @default.
- W2901312299 hasAuthorship W2901312299A5053863947 @default.
- W2901312299 hasAuthorship W2901312299A5070473172 @default.
- W2901312299 hasConcept C126322002 @default.
- W2901312299 hasConcept C134018914 @default.
- W2901312299 hasConcept C16685009 @default.
- W2901312299 hasConcept C2777632594 @default.
- W2901312299 hasConcept C2778248108 @default.
- W2901312299 hasConcept C2779279991 @default.
- W2901312299 hasConcept C2780091579 @default.
- W2901312299 hasConcept C2781087480 @default.
- W2901312299 hasConcept C42407357 @default.
- W2901312299 hasConcept C71315377 @default.
- W2901312299 hasConcept C71924100 @default.
- W2901312299 hasConceptScore W2901312299C126322002 @default.
- W2901312299 hasConceptScore W2901312299C134018914 @default.
- W2901312299 hasConceptScore W2901312299C16685009 @default.
- W2901312299 hasConceptScore W2901312299C2777632594 @default.
- W2901312299 hasConceptScore W2901312299C2778248108 @default.
- W2901312299 hasConceptScore W2901312299C2779279991 @default.
- W2901312299 hasConceptScore W2901312299C2780091579 @default.
- W2901312299 hasConceptScore W2901312299C2781087480 @default.
- W2901312299 hasConceptScore W2901312299C42407357 @default.
- W2901312299 hasConceptScore W2901312299C71315377 @default.
- W2901312299 hasConceptScore W2901312299C71924100 @default.
- W2901312299 hasFunder F4320325902 @default.
- W2901312299 hasLocation W29013122991 @default.
- W2901312299 hasLocation W29013122992 @default.
- W2901312299 hasOpenAccess W2901312299 @default.
- W2901312299 hasPrimaryLocation W29013122991 @default.
- W2901312299 hasRelatedWork W1968957384 @default.
- W2901312299 hasRelatedWork W2080124875 @default.
- W2901312299 hasRelatedWork W2110409614 @default.
- W2901312299 hasRelatedWork W2132624353 @default.
- W2901312299 hasRelatedWork W2164870966 @default.
- W2901312299 hasRelatedWork W2320823592 @default.
- W2901312299 hasRelatedWork W2597230491 @default.
- W2901312299 hasRelatedWork W2978852710 @default.
- W2901312299 hasRelatedWork W3188828249 @default.
- W2901312299 hasRelatedWork W4200019139 @default.
- W2901312299 hasVolume "124" @default.
- W2901312299 isParatext "false" @default.
- W2901312299 isRetracted "false" @default.
- W2901312299 magId "2901312299" @default.
- W2901312299 workType "article" @default.