FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2901471389> ?p ?o ?g. }

• W2901471389 endingPage "1229" @default.
• W2901471389 startingPage "1224" @default.
• W2901471389 abstract "Objective To quantify the degree of lethal and sublethal damage to red blood cells (RBCs) by cell saver (CS) processing among different conditions of shed blood in cardiac surgery. Design Prospective randomized, double-blinded, controlled study. Setting Single university hospital. Participants Twenty rabbits were divided randomly into non-heparinized and heparinized groups. Thereafter, each group was subdivided into non-gauze and gauze groups based on whether the blood was collected with gauze and squeezed out. Interventions Blood from each group was aspirated directly from the heart and underwent CS processing. Mechanical fragility index (MFI) and percent hemolysis were measured pre- and post-CS processing. Measurements and Main Results In RBCs after CS processing, the MFI and percent hemolysis were increased significantly in both the non-heparinized and heparinized groups compared to pre-CS processing. The MFI was significantly higher in the heparinized group than in the non-heparinized group (p = 0.002). However, no differences in percent hemolysis were detected between groups (p = 0.696). The MFI and percent hemolysis of the non-gauze and gauze groups did not differ. Conclusion This study reports the increase in sublethal and lethal injuries to RBCs from heparinized and non-heparinized blood after CS processing. CS-processed heparinized blood contained more sublethally injured RBCs compared to CS-processed non-heparinized blood. RBCs collected by squeezing blood-saturated gauze did not exhibit additional trauma. Further investigation is required to determine the clinical implications of transfusing rescued but injured RBCs using a CS. To quantify the degree of lethal and sublethal damage to red blood cells (RBCs) by cell saver (CS) processing among different conditions of shed blood in cardiac surgery. Prospective randomized, double-blinded, controlled study. Single university hospital. Twenty rabbits were divided randomly into non-heparinized and heparinized groups. Thereafter, each group was subdivided into non-gauze and gauze groups based on whether the blood was collected with gauze and squeezed out. Blood from each group was aspirated directly from the heart and underwent CS processing. Mechanical fragility index (MFI) and percent hemolysis were measured pre- and post-CS processing. In RBCs after CS processing, the MFI and percent hemolysis were increased significantly in both the non-heparinized and heparinized groups compared to pre-CS processing. The MFI was significantly higher in the heparinized group than in the non-heparinized group (p = 0.002). However, no differences in percent hemolysis were detected between groups (p = 0.696). The MFI and percent hemolysis of the non-gauze and gauze groups did not differ. This study reports the increase in sublethal and lethal injuries to RBCs from heparinized and non-heparinized blood after CS processing. CS-processed heparinized blood contained more sublethally injured RBCs compared to CS-processed non-heparinized blood. RBCs collected by squeezing blood-saturated gauze did not exhibit additional trauma. Further investigation is required to determine the clinical implications of transfusing rescued but injured RBCs using a CS." @default.
• W2901471389 created "2018-11-29" @default.
• W2901471389 creator A5025819517 @default.
• W2901471389 creator A5030983617 @default.
• W2901471389 creator A5037516976 @default.
• W2901471389 creator A5046425667 @default.
• W2901471389 creator A5047490140 @default.
• W2901471389 creator A5086658767 @default.
• W2901471389 date "2019-05-01" @default.
• W2901471389 modified "2023-09-28" @default.
• W2901471389 title "Fragility of Red Blood Cells Collected Under Different Conditions With a Cell Saver Device" @default.
• W2901471389 cites W1512818719 @default.
• W2901471389 cites W1528828515 @default.
• W2901471389 cites W1981545929 @default.
• W2901471389 cites W1983749008 @default.
• W2901471389 cites W1984830970 @default.
• W2901471389 cites W1986294961 @default.
• W2901471389 cites W1992258781 @default.
• W2901471389 cites W1994625311 @default.
• W2901471389 cites W2009046524 @default.
• W2901471389 cites W2011620704 @default.
• W2901471389 cites W2012272453 @default.
• W2901471389 cites W2022839606 @default.
• W2901471389 cites W2025296446 @default.
• W2901471389 cites W2036273335 @default.
• W2901471389 cites W2058173505 @default.
• W2901471389 cites W2074799478 @default.
• W2901471389 cites W2092184938 @default.
• W2901471389 cites W2096876696 @default.
• W2901471389 cites W2119378143 @default.
• W2901471389 cites W2122036831 @default.
• W2901471389 cites W2126773677 @default.
• W2901471389 cites W2145415654 @default.
• W2901471389 cites W2146831862 @default.
• W2901471389 cites W2400840714 @default.
• W2901471389 cites W4385369784 @default.
• W2901471389 cites W2299813552 @default.
• W2901471389 doi "https://doi.org/10.1053/j.jvca.2018.11.019" @default.
• W2901471389 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30655204" @default.
• W2901471389 hasPublicationYear "2019" @default.
• W2901471389 type Work @default.
• W2901471389 sameAs 2901471389 @default.
• W2901471389 citedByCount "5" @default.
• W2901471389 countsByYear W29014713892020 @default.
• W2901471389 countsByYear W29014713892022 @default.
• W2901471389 crossrefType "journal-article" @default.
• W2901471389 hasAuthorship W2901471389A5025819517 @default.
• W2901471389 hasAuthorship W2901471389A5030983617 @default.
• W2901471389 hasAuthorship W2901471389A5037516976 @default.
• W2901471389 hasAuthorship W2901471389A5046425667 @default.
• W2901471389 hasAuthorship W2901471389A5047490140 @default.
• W2901471389 hasAuthorship W2901471389A5086658767 @default.
• W2901471389 hasConcept C126322002 @default.
• W2901471389 hasConcept C141071460 @default.
• W2901471389 hasConcept C147509754 @default.
• W2901471389 hasConcept C1621761 @default.
• W2901471389 hasConcept C2776557347 @default.
• W2901471389 hasConcept C2778205648 @default.
• W2901471389 hasConcept C2779902561 @default.
• W2901471389 hasConcept C42219234 @default.
• W2901471389 hasConcept C71924100 @default.
• W2901471389 hasConceptScore W2901471389C126322002 @default.
• W2901471389 hasConceptScore W2901471389C141071460 @default.
• W2901471389 hasConceptScore W2901471389C147509754 @default.
• W2901471389 hasConceptScore W2901471389C1621761 @default.
• W2901471389 hasConceptScore W2901471389C2776557347 @default.
• W2901471389 hasConceptScore W2901471389C2778205648 @default.
• W2901471389 hasConceptScore W2901471389C2779902561 @default.
• W2901471389 hasConceptScore W2901471389C42219234 @default.
• W2901471389 hasConceptScore W2901471389C71924100 @default.
• W2901471389 hasIssue "5" @default.
• W2901471389 hasLocation W29014713891 @default.
• W2901471389 hasLocation W29014713892 @default.
• W2901471389 hasOpenAccess W2901471389 @default.
• W2901471389 hasPrimaryLocation W29014713891 @default.
• W2901471389 hasRelatedWork W1516743911 @default.
• W2901471389 hasRelatedWork W1968304053 @default.
• W2901471389 hasRelatedWork W1972774396 @default.
• W2901471389 hasRelatedWork W2035024531 @default.
• W2901471389 hasRelatedWork W2129705938 @default.
• W2901471389 hasRelatedWork W2169112752 @default.
• W2901471389 hasRelatedWork W2347648222 @default.
• W2901471389 hasRelatedWork W2351357577 @default.
• W2901471389 hasRelatedWork W2360088413 @default.
• W2901471389 hasRelatedWork W2518728882 @default.
• W2901471389 hasVolume "33" @default.
• W2901471389 isParatext "false" @default.
• W2901471389 isRetracted "false" @default.
• W2901471389 magId "2901471389" @default.
• W2901471389 workType "article" @default.