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• W2901479987 abstract "Abstract Background and Aim: Rapid deployment bioprostheses (RDB) have been recently introduced into clinical practice. Aim of this multicenter retrospective study was to evaluate early and mid-term outcomes of aortic valve replacement (AVR) with RDB. Methods: Data from a National Registry that includes patients undergoing AVR with RDB in Italy were analyzed. Univariate and multivariable analysis were performed to identify independent predictors of mortality. Kaplan-Meier method was used for survival analysis. Results: A total of 1158 patients (21 centers, April 2012-March 2018) were included. Nearly one third of patients (368 patients, 31.7%) underwent combined operations and 487 (61.6%) of the 790 patients who underwent isolated AVR received a minimally invasive approach. Median cross-clamp time for isolated AVR was 58 minutes (IQR: 45–71). Device success was 97.8% (1132 patients). Permanent pace-maker implantation was 6.7% (78 patients). Thirty-day overall mortality occurred in 24 patients (2.1%). At discharge, trace-mild and moderate paravalvular leak were found in 98 (8.5%) and in 8 (0.7%) patients, respectively. Median follow-up was 351 days (IQR: 96–654). Figure 1A shows hemodynamic performance over time. Kaplan-Meier survival was 95.8 ± 0.6% and 88 ± 2.4% at 1 and 4 years, respectively (Fig. 1B). At follow-up, 1078 patients were in NYHA class 1–2 (98.4%). Multivariable analysis identified as independent predictors of mortality: age (OR:1.071, 95%CI: 1.006–1.139; p = 0.0307) and preoperative atrial fibrillation (OR:2.693, 95%CI: 1.204–6.022; p = 0.0158). Conclusions: RDB provide good early and mid-term clinical and hemodynamic outcomes. These devices may be considered as a reasonable alternative to conventional bioprostheses especially in minimally invasive or in combined operations." @default.
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• W2901479987 date "2018-11-01" @default.
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• W2901479987 title "OC09 CLINICAL AND HEMODYNAMIC OUTCOMES AFTER AORTIC VALVE REPLACEMENT WITH RAPID-DEPLOYMENT BIOPROSTHESES: RESULTS FROM AN ITALIAN NATIONAL REGISTRY" @default.
• W2901479987 doi "https://doi.org/10.2459/01.jcm.0000549901.50273.24" @default.
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