FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2901512930> ?p ?o ?g. }

• W2901512930 endingPage "666" @default.
• W2901512930 startingPage "658" @default.
• W2901512930 abstract "Prospective investigations for the frequency of hypoattenuated leaflet thickening (HALT) and its clinical implications in transcatheter aortic valve implantation (TAVI) patients are limited. We initiated a prospective screening program of TAVI patients for HALT beginning in July 2015. Eligible patients were evaluated with gated, contrast-enhanced multidetector computed tomography within 30 days of TAVI, and examined for HALT and clinical outcomes. During the study period, 287 patients (81 ± 8 years; 53% men) who underwent TAVI with commercially approved devices were examined. Overall, 26 patients (9.1%) had occurrence of HALT, and only one of these patients had detectable hemodynamic changes on echocardiography at diagnosis. Notably, 9 of 26 HALT patients had been receiving warfarin, however, the HALT patients more often had subtherapeutic international normalized ratio whereas using warfarin than patients without HALT on index multidetector computed tomography imaging (p = 0.01). Patients who developed HALT had lower baseline aortic gradient, valvuloarterial impedance, and peak aortic velocity, and more commonly had been treated with balloon-expandable valves (73% of all HALT cases) with a higher incidence among those who received larger prostheses. All patients with HALT were placed on anticoagulation at diagnosis, and valvular function remained unchanged at follow-up. Two patients with HALT (7.7%) experienced ischemic stroke. A statistical trend for more major adverse clinical events was present in HALT patients. In conclusion, HALT was detected in 9% of TAVI cases in this prospective observational cohort, with a greater frequency in patients with large, balloon-expandable prostheses. Prospective screening may be considered as early HALT is reversible by timely therapeutic anticoagulation. Prospective investigations for the frequency of hypoattenuated leaflet thickening (HALT) and its clinical implications in transcatheter aortic valve implantation (TAVI) patients are limited. We initiated a prospective screening program of TAVI patients for HALT beginning in July 2015. Eligible patients were evaluated with gated, contrast-enhanced multidetector computed tomography within 30 days of TAVI, and examined for HALT and clinical outcomes. During the study period, 287 patients (81 ± 8 years; 53% men) who underwent TAVI with commercially approved devices were examined. Overall, 26 patients (9.1%) had occurrence of HALT, and only one of these patients had detectable hemodynamic changes on echocardiography at diagnosis. Notably, 9 of 26 HALT patients had been receiving warfarin, however, the HALT patients more often had subtherapeutic international normalized ratio whereas using warfarin than patients without HALT on index multidetector computed tomography imaging (p = 0.01). Patients who developed HALT had lower baseline aortic gradient, valvuloarterial impedance, and peak aortic velocity, and more commonly had been treated with balloon-expandable valves (73% of all HALT cases) with a higher incidence among those who received larger prostheses. All patients with HALT were placed on anticoagulation at diagnosis, and valvular function remained unchanged at follow-up. Two patients with HALT (7.7%) experienced ischemic stroke. A statistical trend for more major adverse clinical events was present in HALT patients. In conclusion, HALT was detected in 9% of TAVI cases in this prospective observational cohort, with a greater frequency in patients with large, balloon-expandable prostheses. Prospective screening may be considered as early HALT is reversible by timely therapeutic anticoagulation." @default.
• W2901512930 created "2018-11-29" @default.
• W2901512930 creator A5008829853 @default.
• W2901512930 creator A5038085166 @default.
• W2901512930 creator A5044611199 @default.
• W2901512930 creator A5059617617 @default.
• W2901512930 creator A5062627938 @default.
• W2901512930 creator A5074584279 @default.
• W2901512930 creator A5080658061 @default.
• W2901512930 creator A5086838432 @default.
• W2901512930 creator A5091728164 @default.
• W2901512930 date "2019-02-01" @default.
• W2901512930 modified "2023-10-13" @default.
• W2901512930 title "Prospective Evaluation for Hypoattenuated Leaflet Thickening Following Transcatheter Aortic Valve Implantation" @default.
• W2901512930 cites W105422400 @default.
• W2901512930 cites W1978121427 @default.
• W2901512930 cites W2001929763 @default.
• W2901512930 cites W2007916462 @default.
• W2901512930 cites W2022311307 @default.
• W2901512930 cites W2037402552 @default.
• W2901512930 cites W2086790953 @default.
• W2901512930 cites W2112045987 @default.
• W2901512930 cites W2254220616 @default.
• W2901512930 cites W2266976287 @default.
• W2901512930 cites W2310246866 @default.
• W2901512930 cites W2318441640 @default.
• W2901512930 cites W2346006474 @default.
• W2901512930 cites W2346972206 @default.
• W2901512930 cites W2514702069 @default.
• W2901512930 cites W2547280979 @default.
• W2901512930 cites W2565451362 @default.
• W2901512930 cites W2596816418 @default.
• W2901512930 cites W2598430163 @default.
• W2901512930 cites W2601913781 @default.
• W2901512930 cites W2604699171 @default.
• W2901512930 cites W2729496411 @default.
• W2901512930 cites W2765106576 @default.
• W2901512930 cites W2768017489 @default.
• W2901512930 cites W2781876810 @default.
• W2901512930 cites W2790479374 @default.
• W2901512930 cites W2794179232 @default.
• W2901512930 cites W4250082639 @default.
• W2901512930 doi "https://doi.org/10.1016/j.amjcard.2018.11.012" @default.
• W2901512930 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30528421" @default.
• W2901512930 hasPublicationYear "2019" @default.
• W2901512930 type Work @default.
• W2901512930 sameAs 2901512930 @default.
• W2901512930 citedByCount "26" @default.
• W2901512930 countsByYear W29015129302020 @default.
• W2901512930 countsByYear W29015129302021 @default.
• W2901512930 countsByYear W29015129302022 @default.
• W2901512930 countsByYear W29015129302023 @default.
• W2901512930 crossrefType "journal-article" @default.
• W2901512930 hasAuthorship W2901512930A5008829853 @default.
• W2901512930 hasAuthorship W2901512930A5038085166 @default.
• W2901512930 hasAuthorship W2901512930A5044611199 @default.
• W2901512930 hasAuthorship W2901512930A5059617617 @default.
• W2901512930 hasAuthorship W2901512930A5062627938 @default.
• W2901512930 hasAuthorship W2901512930A5074584279 @default.
• W2901512930 hasAuthorship W2901512930A5080658061 @default.
• W2901512930 hasAuthorship W2901512930A5086838432 @default.
• W2901512930 hasAuthorship W2901512930A5091728164 @default.
• W2901512930 hasConcept C126322002 @default.
• W2901512930 hasConcept C126838900 @default.
• W2901512930 hasConcept C139059822 @default.
• W2901512930 hasConcept C141071460 @default.
• W2901512930 hasConcept C164705383 @default.
• W2901512930 hasConcept C188816634 @default.
• W2901512930 hasConcept C2780714102 @default.
• W2901512930 hasConcept C71924100 @default.
• W2901512930 hasConceptScore W2901512930C126322002 @default.
• W2901512930 hasConceptScore W2901512930C126838900 @default.
• W2901512930 hasConceptScore W2901512930C139059822 @default.
• W2901512930 hasConceptScore W2901512930C141071460 @default.
• W2901512930 hasConceptScore W2901512930C164705383 @default.
• W2901512930 hasConceptScore W2901512930C188816634 @default.
• W2901512930 hasConceptScore W2901512930C2780714102 @default.
• W2901512930 hasConceptScore W2901512930C71924100 @default.
• W2901512930 hasIssue "4" @default.
• W2901512930 hasLocation W29015129301 @default.
• W2901512930 hasLocation W29015129302 @default.
• W2901512930 hasOpenAccess W2901512930 @default.
• W2901512930 hasPrimaryLocation W29015129301 @default.
• W2901512930 hasRelatedWork W1531601525 @default.
• W2901512930 hasRelatedWork W2276026673 @default.
• W2901512930 hasRelatedWork W2758277628 @default.
• W2901512930 hasRelatedWork W2935909890 @default.
• W2901512930 hasRelatedWork W2948807893 @default.
• W2901512930 hasRelatedWork W3173606202 @default.
• W2901512930 hasRelatedWork W3183948672 @default.
• W2901512930 hasRelatedWork W4387497383 @default.
• W2901512930 hasRelatedWork W2778153218 @default.
• W2901512930 hasRelatedWork W3110381201 @default.
• W2901512930 hasVolume "123" @default.
• W2901512930 isParatext "false" @default.
• W2901512930 isRetracted "false" @default.
• W2901512930 magId "2901512930" @default.
• W2901512930 workType "article" @default.