Matches in SemOpenAlex for { <https://semopenalex.org/work/W2901604565> ?p ?o ?g. }
- W2901604565 endingPage "204" @default.
- W2901604565 startingPage "197" @default.
- W2901604565 abstract "Background: Hedgehog pathway plays a crucial role in the neovascularisation and angiogenesis during the embryonic stage in humans. Three genes of hedgehog protein isolated from humans are Sonic hedgehog, Desert hedgehog and Indian hedgehog gene. Two G-protein coupled receptors identified in the sonic hedgehog pathway served as patched receptor and smoothened receptor. Materials and Methods: Particularly, sonic hedgehog gene plays a versatile role in cellular homeostasis and can be a novel therapeutic target in the prevention of cardiovascular disorders. Further various sonic hedgehog modulators have been reported working as futuristic drug molecules in the modulation of cardiovascular dysfunctions. Results: However, there was limited literature availability that has summarized the possible mechanism of targeting Sonic hedgehog signaling pathway. Conclusion: Thus, the present review is aimed at exploring the role of targeting sonic hedgehog protein signaling and modulators as well as to enlighten that how targeting sonic hedgehog protein involves in the amelioration of atherosclerosis, ischemic heart diseases, vascular endothelial dysfunction, heart failure and congenital heart diseases." @default.
- W2901604565 created "2018-11-29" @default.
- W2901604565 creator A5057728839 @default.
- W2901604565 creator A5066938946 @default.
- W2901604565 creator A5081302416 @default.
- W2901604565 date "2020-12-01" @default.
- W2901604565 modified "2023-09-27" @default.
- W2901604565 title "Sonic Hedgehog Signaling Activation Promotes Cardioprotective Strategies" @default.
- W2901604565 cites W1498587827 @default.
- W2901604565 cites W1650648713 @default.
- W2901604565 cites W1965575731 @default.
- W2901604565 cites W1969790984 @default.
- W2901604565 cites W1970040125 @default.
- W2901604565 cites W1970353708 @default.
- W2901604565 cites W1978350626 @default.
- W2901604565 cites W1991209451 @default.
- W2901604565 cites W1994155034 @default.
- W2901604565 cites W2000572318 @default.
- W2901604565 cites W2002233575 @default.
- W2901604565 cites W2004559089 @default.
- W2901604565 cites W2005859137 @default.
- W2901604565 cites W2006583445 @default.
- W2901604565 cites W2007535582 @default.
- W2901604565 cites W2009404031 @default.
- W2901604565 cites W2015722572 @default.
- W2901604565 cites W2022430355 @default.
- W2901604565 cites W2027082110 @default.
- W2901604565 cites W2040182956 @default.
- W2901604565 cites W2045070406 @default.
- W2901604565 cites W2056842941 @default.
- W2901604565 cites W2067593077 @default.
- W2901604565 cites W2068040345 @default.
- W2901604565 cites W2090403899 @default.
- W2901604565 cites W2091307634 @default.
- W2901604565 cites W2094569187 @default.
- W2901604565 cites W2098440313 @default.
- W2901604565 cites W2100825082 @default.
- W2901604565 cites W2101266961 @default.
- W2901604565 cites W2105383133 @default.
- W2901604565 cites W2108228774 @default.
- W2901604565 cites W2118337496 @default.
- W2901604565 cites W2119092533 @default.
- W2901604565 cites W2120609852 @default.
- W2901604565 cites W2120788476 @default.
- W2901604565 cites W2120972584 @default.
- W2901604565 cites W2124354752 @default.
- W2901604565 cites W2124936055 @default.
- W2901604565 cites W2128638548 @default.
- W2901604565 cites W2142181417 @default.
- W2901604565 cites W2150035538 @default.
- W2901604565 cites W2151871918 @default.
- W2901604565 cites W2152745230 @default.
- W2901604565 cites W2158982524 @default.
- W2901604565 cites W2159970646 @default.
- W2901604565 cites W2163732935 @default.
- W2901604565 cites W2167661646 @default.
- W2901604565 cites W2403309779 @default.
- W2901604565 cites W2474599166 @default.
- W2901604565 cites W2504019766 @default.
- W2901604565 cites W2587733078 @default.
- W2901604565 cites W2614186512 @default.
- W2901604565 cites W2670801209 @default.
- W2901604565 cites W2734468993 @default.
- W2901604565 cites W2754975954 @default.
- W2901604565 cites W2765125422 @default.
- W2901604565 cites W2765416004 @default.
- W2901604565 cites W2766733553 @default.
- W2901604565 cites W2770404853 @default.
- W2901604565 cites W2774410954 @default.
- W2901604565 cites W2793462451 @default.
- W2901604565 cites W4385366858 @default.
- W2901604565 cites W75086179 @default.
- W2901604565 doi "https://doi.org/10.2174/1574362413666181113124958" @default.
- W2901604565 hasPublicationYear "2020" @default.
- W2901604565 type Work @default.
- W2901604565 sameAs 2901604565 @default.
- W2901604565 citedByCount "0" @default.
- W2901604565 crossrefType "journal-article" @default.
- W2901604565 hasAuthorship W2901604565A5057728839 @default.
- W2901604565 hasAuthorship W2901604565A5066938946 @default.
- W2901604565 hasAuthorship W2901604565A5081302416 @default.
- W2901604565 hasConcept C120407494 @default.
- W2901604565 hasConcept C145837895 @default.
- W2901604565 hasConcept C169760540 @default.
- W2901604565 hasConcept C2776637008 @default.
- W2901604565 hasConcept C2777994357 @default.
- W2901604565 hasConcept C2778539099 @default.
- W2901604565 hasConcept C62478195 @default.
- W2901604565 hasConcept C71924100 @default.
- W2901604565 hasConcept C86803240 @default.
- W2901604565 hasConcept C88498014 @default.
- W2901604565 hasConcept C95444343 @default.
- W2901604565 hasConceptScore W2901604565C120407494 @default.
- W2901604565 hasConceptScore W2901604565C145837895 @default.
- W2901604565 hasConceptScore W2901604565C169760540 @default.
- W2901604565 hasConceptScore W2901604565C2776637008 @default.
- W2901604565 hasConceptScore W2901604565C2777994357 @default.
- W2901604565 hasConceptScore W2901604565C2778539099 @default.