FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2901614095> ?p ?o ?g. }

• W2901614095 endingPage "28" @default.
• W2901614095 startingPage "21" @default.
• W2901614095 abstract "The cationic polyelectrolyte pDADMAC is widely used in biopharmaceutical industry as a flocculating agent to enhance clarification throughput and downstream filtration operations. Due to the possible toxicity, pDADMAC should be assessed for an acceptable residual level to ascertain the safety of the product to patients. The strong protein-polyelectrolyte interaction, however, can negatively affect sensitivity and accuracy of measurements. This paper reports on the application of size exclusion (SE) chromatography coupled to evaporative light scattering detector (ELSD) to the quantitative determination of pDADMAC in monoclonal antibody formulations and in process intermediates during downstream purification. The SE chromatography was performed under isocratic condition with a mobile phase consisting of 0.1% TFA in water (90%) and acetonitrile (10%) at a flow rate of 0.4 ml/min. A quantification limit (S/N = 10) of 0.85 ppm was achieved in sample matrix, which is sufficiently low for the trace analysis of this compound in protein-containing samples." @default.
• W2901614095 created "2018-11-29" @default.
• W2901614095 creator A5012202031 @default.
• W2901614095 creator A5027620753 @default.
• W2901614095 creator A5031141945 @default.
• W2901614095 creator A5052544447 @default.
• W2901614095 creator A5058951492 @default.
• W2901614095 date "2019-01-01" @default.
• W2901614095 modified "2023-09-25" @default.
• W2901614095 title "Determination of residual poly diallyldimethylammonium chloride (pDADMAC) in monoclonal antibody formulations by size exclusion chromatography and evaporative light scattering detector" @default.
• W2901614095 cites W1609743519 @default.
• W2901614095 cites W1918215484 @default.
• W2901614095 cites W1977803288 @default.
• W2901614095 cites W1992444943 @default.
• W2901614095 cites W2019396869 @default.
• W2901614095 cites W2023405769 @default.
• W2901614095 cites W2027783748 @default.
• W2901614095 cites W2034963044 @default.
• W2901614095 cites W2036384186 @default.
• W2901614095 cites W2040224624 @default.
• W2901614095 cites W2044815719 @default.
• W2901614095 cites W2046744974 @default.
• W2901614095 cites W2065960941 @default.
• W2901614095 cites W2067643068 @default.
• W2901614095 cites W2071392297 @default.
• W2901614095 cites W2086069830 @default.
• W2901614095 cites W2086646956 @default.
• W2901614095 cites W2090480857 @default.
• W2901614095 cites W2110245140 @default.
• W2901614095 cites W2116412217 @default.
• W2901614095 cites W2144314861 @default.
• W2901614095 cites W2462712249 @default.
• W2901614095 cites W2767759534 @default.
• W2901614095 doi "https://doi.org/10.1016/j.biologicals.2018.11.002" @default.
• W2901614095 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30447860" @default.
• W2901614095 hasPublicationYear "2019" @default.
• W2901614095 type Work @default.
• W2901614095 sameAs 2901614095 @default.
• W2901614095 citedByCount "1" @default.
• W2901614095 countsByYear W29016140952020 @default.
• W2901614095 crossrefType "journal-article" @default.
• W2901614095 hasAuthorship W2901614095A5012202031 @default.
• W2901614095 hasAuthorship W2901614095A5027620753 @default.
• W2901614095 hasAuthorship W2901614095A5031141945 @default.
• W2901614095 hasAuthorship W2901614095A5052544447 @default.
• W2901614095 hasAuthorship W2901614095A5058951492 @default.
• W2901614095 hasConcept C105795698 @default.
• W2901614095 hasConcept C106487976 @default.
• W2901614095 hasConcept C110084920 @default.
• W2901614095 hasConcept C119128265 @default.
• W2901614095 hasConcept C120456961 @default.
• W2901614095 hasConcept C120665830 @default.
• W2901614095 hasConcept C121332964 @default.
• W2901614095 hasConcept C128489963 @default.
• W2901614095 hasConcept C153356533 @default.
• W2901614095 hasConcept C178790620 @default.
• W2901614095 hasConcept C179998833 @default.
• W2901614095 hasConcept C181199279 @default.
• W2901614095 hasConcept C185592680 @default.
• W2901614095 hasConcept C191486275 @default.
• W2901614095 hasConcept C193363816 @default.
• W2901614095 hasConcept C33923547 @default.
• W2901614095 hasConcept C43617362 @default.
• W2901614095 hasConcept C521977710 @default.
• W2901614095 hasConceptScore W2901614095C105795698 @default.
• W2901614095 hasConceptScore W2901614095C106487976 @default.
• W2901614095 hasConceptScore W2901614095C110084920 @default.
• W2901614095 hasConceptScore W2901614095C119128265 @default.
• W2901614095 hasConceptScore W2901614095C120456961 @default.
• W2901614095 hasConceptScore W2901614095C120665830 @default.
• W2901614095 hasConceptScore W2901614095C121332964 @default.
• W2901614095 hasConceptScore W2901614095C128489963 @default.
• W2901614095 hasConceptScore W2901614095C153356533 @default.
• W2901614095 hasConceptScore W2901614095C178790620 @default.
• W2901614095 hasConceptScore W2901614095C179998833 @default.
• W2901614095 hasConceptScore W2901614095C181199279 @default.
• W2901614095 hasConceptScore W2901614095C185592680 @default.
• W2901614095 hasConceptScore W2901614095C191486275 @default.
• W2901614095 hasConceptScore W2901614095C193363816 @default.
• W2901614095 hasConceptScore W2901614095C33923547 @default.
• W2901614095 hasConceptScore W2901614095C43617362 @default.
• W2901614095 hasConceptScore W2901614095C521977710 @default.
• W2901614095 hasFunder F4320327589 @default.
• W2901614095 hasLocation W29016140951 @default.
• W2901614095 hasLocation W29016140952 @default.
• W2901614095 hasOpenAccess W2901614095 @default.
• W2901614095 hasPrimaryLocation W29016140951 @default.
• W2901614095 hasRelatedWork W1982625015 @default.
• W2901614095 hasRelatedWork W2001423549 @default.
• W2901614095 hasRelatedWork W2022878083 @default.
• W2901614095 hasRelatedWork W2026619427 @default.
• W2901614095 hasRelatedWork W2079187157 @default.
• W2901614095 hasRelatedWork W2088923234 @default.
• W2901614095 hasRelatedWork W2362334314 @default.
• W2901614095 hasRelatedWork W2364345122 @default.
• W2901614095 hasRelatedWork W3085245795 @default.
• W2901614095 hasRelatedWork W2461628107 @default.
• W2901614095 hasVolume "57" @default.

• next