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• W2901654380 endingPage "22" @default.
• W2901654380 startingPage "9" @default.
• W2901654380 abstract "Cancer immunotherapy using immune-checkpoint inhibitors has emerged as an effective treatment option for a variety of advanced cancers in the past decade. Because of the distinct mechanisms of immunotherapy that activate the host immunity to treat cancers, unconventional immune-related phenomena are encountered in terms of tumor response and progression, as well as drug toxicity. Imaging plays an important role in objectively characterizing immune-related tumor responses and progression and in detecting and monitoring immune-related adverse events. Moreover, emerging data suggest a promise for molecular imaging that can visualize the specific target molecules involved in immune-checkpoint pathways. In this article, the background and current status of cancer immunotherapy are summarized, and the current methods for imaging evaluations of immune-related responses and toxicities are reviewed along with their limitations and pitfalls. Emerging approaches with molecular imaging are also discussed as a future direction to address unmet needs. © RSNA, 2018" @default.
• W2901654380 created "2018-11-29" @default.
• W2901654380 creator A5065789326 @default.
• W2901654380 creator A5069854182 @default.
• W2901654380 creator A5084967339 @default.
• W2901654380 date "2019-01-01" @default.
• W2901654380 modified "2023-10-11" @default.
• W2901654380 title "Imaging of Cancer Immunotherapy: Current Approaches and Future Directions" @default.
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• W2901654380 doi "https://doi.org/10.1148/radiol.2018181349" @default.

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