Matches in SemOpenAlex for { <https://semopenalex.org/work/W2901671710> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2901671710 endingPage "e29" @default.
- W2901671710 startingPage "e29" @default.
- W2901671710 abstract "Abstract Background: The “Organ Care System (OCS)- Heart”-TransMedics (TM) is the only clinical platform for ex-vivo perfusion of human donor hearts, preserving the graft in a warm beating state. AIM: To analyze results of HTX performed with OCS. Methods: From 2015 to 2018, 7 patients (mean age: 46y) received a donor heart (mean age: 39y) preserved with the OCS-Heart system. Ischemic, cardiopulmonary (CPB) bypass time and day-0/day-1 CK-MB levels (TM-group) were compared with those of 95 patients transplanted with the cold static storage (CSS-group). The OCS was used for expected long ischemic times or for adverse donor (cardiac arrest) or recipient (infected LVAD, ECMO and unusual anatomy) features. Results: Mean out-of-the-body perfusion time was 296 minutes. Overall ischemic time was 124 (TM-group) vs. 187 minutes in the CSS-group (P = 0.01). The OCS allowed to spare 159 minutes of estimated ischemia. D0/D1 CK-MB was 115 and 36 vs. 125 and 47 ng/ml in the CSS-group (P = NS). ICU stay was 20 days. Two patients died for hemorragic shock (LVAD recipient) and for multiorgan failure. One patient developed a severe right failure, treated by mechanical assistance, weaned after 8 days. Five recipients are alive at a mean FU of 18 months. Conclusions: Ex-vivo perfusion of donor hearts is technically safe and permits a significant reduction of the ischemic time. A trend toward reduction of myocardial damage was observed when compared to CSS. The real impact in unfavourable donor-recipient combination needs further investigations. A potential expansion of donors’pool is predictable with this innovative system." @default.
- W2901671710 created "2018-11-29" @default.
- W2901671710 creator A5017787365 @default.
- W2901671710 creator A5021225362 @default.
- W2901671710 creator A5022373044 @default.
- W2901671710 creator A5028080438 @default.
- W2901671710 creator A5047134412 @default.
- W2901671710 creator A5054343162 @default.
- W2901671710 creator A5071515504 @default.
- W2901671710 creator A5087629025 @default.
- W2901671710 date "2018-11-01" @default.
- W2901671710 modified "2023-10-16" @default.
- W2901671710 title "OC77 THE OCS HEART SYSTEM FOR EX-VIVO PERFUSION OF THE DONOR HEART" @default.
- W2901671710 doi "https://doi.org/10.2459/01.jcm.0000549924.39078.10" @default.
- W2901671710 hasPublicationYear "2018" @default.
- W2901671710 type Work @default.
- W2901671710 sameAs 2901671710 @default.
- W2901671710 citedByCount "0" @default.
- W2901671710 crossrefType "journal-article" @default.
- W2901671710 hasAuthorship W2901671710A5017787365 @default.
- W2901671710 hasAuthorship W2901671710A5021225362 @default.
- W2901671710 hasAuthorship W2901671710A5022373044 @default.
- W2901671710 hasAuthorship W2901671710A5028080438 @default.
- W2901671710 hasAuthorship W2901671710A5047134412 @default.
- W2901671710 hasAuthorship W2901671710A5054343162 @default.
- W2901671710 hasAuthorship W2901671710A5071515504 @default.
- W2901671710 hasAuthorship W2901671710A5087629025 @default.
- W2901671710 hasConcept C126322002 @default.
- W2901671710 hasConcept C141071460 @default.
- W2901671710 hasConcept C146957229 @default.
- W2901671710 hasConcept C150903083 @default.
- W2901671710 hasConcept C164705383 @default.
- W2901671710 hasConcept C197934379 @default.
- W2901671710 hasConcept C207001950 @default.
- W2901671710 hasConcept C26291073 @default.
- W2901671710 hasConcept C2778198053 @default.
- W2901671710 hasConcept C2778881276 @default.
- W2901671710 hasConcept C2781300812 @default.
- W2901671710 hasConcept C42219234 @default.
- W2901671710 hasConcept C71924100 @default.
- W2901671710 hasConcept C86803240 @default.
- W2901671710 hasConceptScore W2901671710C126322002 @default.
- W2901671710 hasConceptScore W2901671710C141071460 @default.
- W2901671710 hasConceptScore W2901671710C146957229 @default.
- W2901671710 hasConceptScore W2901671710C150903083 @default.
- W2901671710 hasConceptScore W2901671710C164705383 @default.
- W2901671710 hasConceptScore W2901671710C197934379 @default.
- W2901671710 hasConceptScore W2901671710C207001950 @default.
- W2901671710 hasConceptScore W2901671710C26291073 @default.
- W2901671710 hasConceptScore W2901671710C2778198053 @default.
- W2901671710 hasConceptScore W2901671710C2778881276 @default.
- W2901671710 hasConceptScore W2901671710C2781300812 @default.
- W2901671710 hasConceptScore W2901671710C42219234 @default.
- W2901671710 hasConceptScore W2901671710C71924100 @default.
- W2901671710 hasConceptScore W2901671710C86803240 @default.
- W2901671710 hasIssue "Supplement 2" @default.
- W2901671710 hasLocation W29016717101 @default.
- W2901671710 hasOpenAccess W2901671710 @default.
- W2901671710 hasPrimaryLocation W29016717101 @default.
- W2901671710 hasRelatedWork W2016187818 @default.
- W2901671710 hasRelatedWork W2081755346 @default.
- W2901671710 hasRelatedWork W2157369237 @default.
- W2901671710 hasRelatedWork W2271356446 @default.
- W2901671710 hasRelatedWork W2393078530 @default.
- W2901671710 hasRelatedWork W2808919779 @default.
- W2901671710 hasRelatedWork W2912862887 @default.
- W2901671710 hasRelatedWork W4210486955 @default.
- W2901671710 hasRelatedWork W4210540426 @default.
- W2901671710 hasRelatedWork W2337520786 @default.
- W2901671710 hasVolume "19" @default.
- W2901671710 isParatext "false" @default.
- W2901671710 isRetracted "false" @default.
- W2901671710 magId "2901671710" @default.
- W2901671710 workType "article" @default.