FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2901781653> ?p ?o ?g. }

• W2901781653 endingPage "2010" @default.
• W2901781653 startingPage "1994" @default.
• W2901781653 abstract "The novel Ca-zeolite/poly(amino acid) (CaY/PAA) composites for bone substitute applications with hemostatic activity were prepared using the in situ melting polymerization method. In this study, Ca-zeolite (CaY) loaded with Ca2+ was obtained from Y-type zeolite (NaY) by ion-exchange method. The properties of the CaY/PAA composites and PAA, including composition, structure, compressive strength, in vitro degradability in phosphate-buffered solution (PBS), bioactivity, cytocompatibility and in vitro coagulation tests were characterized and investigated. The results showed that compressive strength of the CaY/PAA composites ranged from 145 to 186 MPa, demonstrating sufficient mechanical strength for load-bearing bone substitute. After soaking in PBS for 16 weeks, the weight loss of 25CaY/PAA and 50CaY/PAA were 4.1 and 1.6 wt%, respectively, and the pH values for CaY/PAA composites increased to about 8.0 in 2 weeks and then gradually stabilized around 7.4, indicating good stability in PBS. Scanning electron microscope and energy dispersive spectrometer results showed that the composites were bioactive and new apatite layers attached on their surfaces. Mesenchymal stem cells (MSCs) exhibited high-proliferation in the extract solution of the CaY/PAA composites and were well spread on the surfaces of the composites. Cells on the CaY/PAA composite groups showed higher alkaline phosphatase (ALP) activity indicating the potential to promote cell differentiation. The in vitro coagulation tests showed that CaY/PAA composites have shorter clotting time and better performance of promoting blood coagulation than other samples, presenting improved hemostatic activity. In summary, the results demonstrated that the CaY/PAA composites had good mechanical strength, stability, bioactivity, cytocompatibility and hemostatic activity for bone substitute applications." @default.
• W2901781653 created "2018-11-29" @default.
• W2901781653 creator A5002823228 @default.
• W2901781653 creator A5048499354 @default.
• W2901781653 creator A5052637428 @default.
• W2901781653 creator A5064909876 @default.
• W2901781653 creator A5091520888 @default.
• W2901781653 date "2018-11-02" @default.
• W2901781653 modified "2023-09-26" @default.
• W2901781653 title "Developing novel Ca-zeolite/poly(amino acid) composites with hemostatic activity for bone substitute applications" @default.
• W2901781653 cites W1543440531 @default.
• W2901781653 cites W1965019468 @default.
• W2901781653 cites W1966481184 @default.
• W2901781653 cites W1971339046 @default.
• W2901781653 cites W1975689906 @default.
• W2901781653 cites W1979560152 @default.
• W2901781653 cites W1979675223 @default.
• W2901781653 cites W1980080472 @default.
• W2901781653 cites W1982973995 @default.
• W2901781653 cites W1984645690 @default.
• W2901781653 cites W1989653618 @default.
• W2901781653 cites W1993186929 @default.
• W2901781653 cites W1993694424 @default.
• W2901781653 cites W1994592753 @default.
• W2901781653 cites W1997676325 @default.
• W2901781653 cites W2001037711 @default.
• W2901781653 cites W2001266063 @default.
• W2901781653 cites W2002141038 @default.
• W2901781653 cites W2009379612 @default.
• W2901781653 cites W2009563273 @default.
• W2901781653 cites W2010473896 @default.
• W2901781653 cites W2011743465 @default.
• W2901781653 cites W2015161884 @default.
• W2901781653 cites W2015670338 @default.
• W2901781653 cites W2021540155 @default.
• W2901781653 cites W2023948506 @default.
• W2901781653 cites W2028738049 @default.
• W2901781653 cites W2030448269 @default.
• W2901781653 cites W2031135117 @default.
• W2901781653 cites W2032630931 @default.
• W2901781653 cites W2032973552 @default.
• W2901781653 cites W2034366411 @default.
• W2901781653 cites W2035127714 @default.
• W2901781653 cites W2036244808 @default.
• W2901781653 cites W2053559938 @default.
• W2901781653 cites W2066375926 @default.
• W2901781653 cites W2068647962 @default.
• W2901781653 cites W2075871009 @default.
• W2901781653 cites W2077095053 @default.
• W2901781653 cites W2077598490 @default.
• W2901781653 cites W2085704231 @default.
• W2901781653 cites W2116459542 @default.
• W2901781653 cites W2129074899 @default.
• W2901781653 cites W2129357775 @default.
• W2901781653 cites W2131579100 @default.
• W2901781653 cites W2143467371 @default.
• W2901781653 cites W2162763139 @default.
• W2901781653 cites W2165031735 @default.
• W2901781653 cites W2166066687 @default.
• W2901781653 cites W2205219562 @default.
• W2901781653 cites W2311421985 @default.
• W2901781653 cites W2315111972 @default.
• W2901781653 cites W2330317414 @default.
• W2901781653 cites W2540910799 @default.
• W2901781653 cites W2607737041 @default.
• W2901781653 cites W4297575537 @default.
• W2901781653 cites W4324262670 @default.
• W2901781653 cites W771496350 @default.
• W2901781653 doi "https://doi.org/10.1080/09205063.2018.1521688" @default.
• W2901781653 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30474514" @default.
• W2901781653 hasPublicationYear "2018" @default.
• W2901781653 type Work @default.
• W2901781653 sameAs 2901781653 @default.
• W2901781653 citedByCount "8" @default.
• W2901781653 countsByYear W29017816532019 @default.
• W2901781653 countsByYear W29017816532020 @default.
• W2901781653 countsByYear W29017816532021 @default.
• W2901781653 countsByYear W29017816532022 @default.
• W2901781653 crossrefType "journal-article" @default.
• W2901781653 hasAuthorship W2901781653A5002823228 @default.
• W2901781653 hasAuthorship W2901781653A5048499354 @default.
• W2901781653 hasAuthorship W2901781653A5052637428 @default.
• W2901781653 hasAuthorship W2901781653A5064909876 @default.
• W2901781653 hasAuthorship W2901781653A5091520888 @default.
• W2901781653 hasConcept C104779481 @default.
• W2901781653 hasConcept C13965031 @default.
• W2901781653 hasConcept C159985019 @default.
• W2901781653 hasConcept C160160445 @default.
• W2901781653 hasConcept C161790260 @default.
• W2901781653 hasConcept C181199279 @default.
• W2901781653 hasConcept C185592680 @default.
• W2901781653 hasConcept C192562407 @default.
• W2901781653 hasConcept C199289684 @default.
• W2901781653 hasConcept C26771246 @default.
• W2901781653 hasConcept C2777746296 @default.
• W2901781653 hasConcept C2778077586 @default.
• W2901781653 hasConcept C30407753 @default.
• W2901781653 hasConcept C55493867 @default.

• next