Matches in SemOpenAlex for { <https://semopenalex.org/work/W2901809364> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2901809364 abstract "Background: Problematic severe asthma (PSA) is defined as poorly controlled asthma despite high levels of prescribed medications. The prevalence in childhood is between 5-10% of asthmatic children; however the amount of resources these patients consume is disproportionately high. PSA can be split into Difficult Asthma (DA) and Severe Therapy Resistant Asthma (STRA). DA is amenable to improvement by addressing relevant adherence, allergy and psychosocial issues. At least 50% of paediatric patients with PSA are classified as DA; with non-adherence being an issue for around half of these patients. Aims: 1. To identify the modifiable causes of non-adherence in children with PSA to inform an adherence intervention. 2. To use the Medical Research Council (MRC) guidance to develop an intervention for children with DA by tailoring support to overcome the perceptual and practical barriers to adhering to treatments, as recommended in the NICE Guidelines. Methods: Study 1: Literature reviews which summarises: 1. The known reasons for non-adherence in children with PSA 2. Effective components of previous asthma adherence interventions Study 2: A secondary analysis will be conducted, using electronic monitoring (SmartInhaler) collected in over 100 children with asthma, to investigate patterns of non-adherence to inform the intervention. Study 3: A mixed-methods cross-sectional study using validated questionnaires and qualitative interviews to identify potentially modifiable factors associated with non-adherence. Study4: The creation of an Intervention Development Group (IDG) consisting of researchers, clinicians and patients. The IDG will use the PhD results to develop an intervention manual. Study 5: Finally, a feasibility and acceptability pilot study of the intervention. Potential Implications: This PhD addresses the crucial question of non-adherence in children with PSA. It is intended that the intervention developed will lead to a multi-site Randomised Control Trial and roll- out within the NHS." @default.
- W2901809364 created "2018-11-29" @default.
- W2901809364 creator A5082240640 @default.
- W2901809364 date "2015-11-10" @default.
- W2901809364 modified "2023-09-24" @default.
- W2901809364 title "Adherence in Children with Problematic Severe Asthma" @default.
- W2901809364 hasPublicationYear "2015" @default.
- W2901809364 type Work @default.
- W2901809364 sameAs 2901809364 @default.
- W2901809364 citedByCount "0" @default.
- W2901809364 crossrefType "journal-article" @default.
- W2901809364 hasAuthorship W2901809364A5082240640 @default.
- W2901809364 hasConcept C118552586 @default.
- W2901809364 hasConcept C126322002 @default.
- W2901809364 hasConcept C150966472 @default.
- W2901809364 hasConcept C159110408 @default.
- W2901809364 hasConcept C1862650 @default.
- W2901809364 hasConcept C187212893 @default.
- W2901809364 hasConcept C199360897 @default.
- W2901809364 hasConcept C27415008 @default.
- W2901809364 hasConcept C2776042228 @default.
- W2901809364 hasConcept C2779256446 @default.
- W2901809364 hasConcept C2780665704 @default.
- W2901809364 hasConcept C41008148 @default.
- W2901809364 hasConcept C512399662 @default.
- W2901809364 hasConcept C71924100 @default.
- W2901809364 hasConceptScore W2901809364C118552586 @default.
- W2901809364 hasConceptScore W2901809364C126322002 @default.
- W2901809364 hasConceptScore W2901809364C150966472 @default.
- W2901809364 hasConceptScore W2901809364C159110408 @default.
- W2901809364 hasConceptScore W2901809364C1862650 @default.
- W2901809364 hasConceptScore W2901809364C187212893 @default.
- W2901809364 hasConceptScore W2901809364C199360897 @default.
- W2901809364 hasConceptScore W2901809364C27415008 @default.
- W2901809364 hasConceptScore W2901809364C2776042228 @default.
- W2901809364 hasConceptScore W2901809364C2779256446 @default.
- W2901809364 hasConceptScore W2901809364C2780665704 @default.
- W2901809364 hasConceptScore W2901809364C41008148 @default.
- W2901809364 hasConceptScore W2901809364C512399662 @default.
- W2901809364 hasConceptScore W2901809364C71924100 @default.
- W2901809364 hasLocation W29018093641 @default.
- W2901809364 hasOpenAccess W2901809364 @default.
- W2901809364 hasPrimaryLocation W29018093641 @default.
- W2901809364 hasRelatedWork W1860761996 @default.
- W2901809364 hasRelatedWork W1982705327 @default.
- W2901809364 hasRelatedWork W2033033547 @default.
- W2901809364 hasRelatedWork W2065089856 @default.
- W2901809364 hasRelatedWork W2093005278 @default.
- W2901809364 hasRelatedWork W2144624630 @default.
- W2901809364 hasRelatedWork W2162272146 @default.
- W2901809364 hasRelatedWork W2167369774 @default.
- W2901809364 hasRelatedWork W2293110635 @default.
- W2901809364 hasRelatedWork W2315453795 @default.
- W2901809364 hasRelatedWork W2406450865 @default.
- W2901809364 hasRelatedWork W2530548490 @default.
- W2901809364 hasRelatedWork W2598376200 @default.
- W2901809364 hasRelatedWork W2996314639 @default.
- W2901809364 hasRelatedWork W3106790191 @default.
- W2901809364 hasRelatedWork W3161800808 @default.
- W2901809364 hasRelatedWork W3181817170 @default.
- W2901809364 hasRelatedWork W31857768 @default.
- W2901809364 hasRelatedWork W3192320919 @default.
- W2901809364 hasRelatedWork W3212487811 @default.
- W2901809364 isParatext "false" @default.
- W2901809364 isRetracted "false" @default.
- W2901809364 magId "2901809364" @default.
- W2901809364 workType "article" @default.