FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2901878503> ?p ?o ?g. }

• W2901878503 endingPage "e1561" @default.
• W2901878503 startingPage "e1557" @default.
• W2901878503 abstract "Brain metastases commonly manifest in patients with cancer, with ∼20%-50% presenting with 1 intracranial lesion. Among patients with 1, small brain metastasis and controlled or absent extracranial disease, it remains unclear whether aggressive intracranial management using neurosurgical resection plus cavity stereotactic radiosurgery/stereotactic radiotherapy (SRS/SRT) rather than SRS/SRT alone is beneficial. In patients with controlled or absent extracranial disease and 1 brain metastasis ≤2 cm in size, we evaluated the effect of surgery plus SRS/SRT compared with SRS/SRT on oncologic outcomes, including overall survival.We retrospectively identified 86 patients with controlled or absent extracranial disease and 1 brain metastasis ≤2 cm in size who had been treated from 2000 to 2015 at our institution. We examined differences in the rates of local and distant failure, use of salvage treatment, and other oncologic outcomes, including all-cause mortality.The baseline characteristics were similar between the 2 cohorts. The median follow-up period for the surviving patients was 38 months. On multivariable analysis, surgical resection plus cavity SRS/SRT was associated with a lower risk of all-cause mortality (hazard ratio, 0.44; 95% confidence interval, 0.19-1.00; P = 0.05) compared with SRS/SRT alone. The 1- and 2-year rates of overall survival were 100% and 88% versus 74% and 52% for surgery plus cavity SRS/SRT versus SRS/SRT alone, respectively.Aggressive, local therapy, including neurosurgical resection, might benefit patients with 1 brain metastasis in the context of controlled or absent systemic disease, even if the lesion in question is small. Further studies are needed to evaluate these associations." @default.
• W2901878503 created "2018-11-29" @default.
• W2901878503 creator A5000323961 @default.
• W2901878503 creator A5003790985 @default.
• W2901878503 creator A5018608069 @default.
• W2901878503 creator A5019509632 @default.
• W2901878503 creator A5022708489 @default.
• W2901878503 creator A5022796764 @default.
• W2901878503 creator A5033481634 @default.
• W2901878503 creator A5036059692 @default.
• W2901878503 creator A5038535548 @default.
• W2901878503 creator A5041898186 @default.
• W2901878503 creator A5043519166 @default.
• W2901878503 creator A5047848562 @default.
• W2901878503 creator A5047888321 @default.
• W2901878503 creator A5051390263 @default.
• W2901878503 creator A5069129452 @default.
• W2901878503 creator A5076665011 @default.
• W2901878503 creator A5085032736 @default.
• W2901878503 date "2019-02-01" @default.
• W2901878503 modified "2023-10-01" @default.
• W2901878503 title "Neurosurgical Resection and Stereotactic Radiation Versus Stereotactic Radiation Alone in Patients with a Single or Solitary Brain Metastasis" @default.
• W2901878503 cites W1976628810 @default.
• W2901878503 cites W2004852620 @default.
• W2901878503 cites W2016908822 @default.
• W2901878503 cites W2018992636 @default.
• W2901878503 cites W2057899218 @default.
• W2901878503 cites W2067259348 @default.
• W2901878503 cites W2128871519 @default.
• W2901878503 cites W2153127029 @default.
• W2901878503 cites W2158757066 @default.
• W2901878503 cites W2158789700 @default.
• W2901878503 cites W2162887147 @default.
• W2901878503 cites W2177244913 @default.
• W2901878503 cites W2292305777 @default.
• W2901878503 cites W2316236000 @default.
• W2901878503 cites W2329793926 @default.
• W2901878503 cites W2533301708 @default.
• W2901878503 cites W2605559873 @default.
• W2901878503 cites W2621196708 @default.
• W2901878503 cites W2726463501 @default.
• W2901878503 doi "https://doi.org/10.1016/j.wneu.2018.11.100" @default.
• W2901878503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30471438" @default.
• W2901878503 hasPublicationYear "2019" @default.
• W2901878503 type Work @default.
• W2901878503 sameAs 2901878503 @default.
• W2901878503 citedByCount "17" @default.
• W2901878503 countsByYear W29018785032019 @default.
• W2901878503 countsByYear W29018785032020 @default.
• W2901878503 countsByYear W29018785032021 @default.
• W2901878503 countsByYear W29018785032022 @default.
• W2901878503 countsByYear W29018785032023 @default.
• W2901878503 crossrefType "journal-article" @default.
• W2901878503 hasAuthorship W2901878503A5000323961 @default.
• W2901878503 hasAuthorship W2901878503A5003790985 @default.
• W2901878503 hasAuthorship W2901878503A5018608069 @default.
• W2901878503 hasAuthorship W2901878503A5019509632 @default.
• W2901878503 hasAuthorship W2901878503A5022708489 @default.
• W2901878503 hasAuthorship W2901878503A5022796764 @default.
• W2901878503 hasAuthorship W2901878503A5033481634 @default.
• W2901878503 hasAuthorship W2901878503A5036059692 @default.
• W2901878503 hasAuthorship W2901878503A5038535548 @default.
• W2901878503 hasAuthorship W2901878503A5041898186 @default.
• W2901878503 hasAuthorship W2901878503A5043519166 @default.
• W2901878503 hasAuthorship W2901878503A5047848562 @default.
• W2901878503 hasAuthorship W2901878503A5047888321 @default.
• W2901878503 hasAuthorship W2901878503A5051390263 @default.
• W2901878503 hasAuthorship W2901878503A5069129452 @default.
• W2901878503 hasAuthorship W2901878503A5076665011 @default.
• W2901878503 hasAuthorship W2901878503A5085032736 @default.
• W2901878503 hasConcept C121608353 @default.
• W2901878503 hasConcept C126322002 @default.
• W2901878503 hasConcept C141071460 @default.
• W2901878503 hasConcept C151730666 @default.
• W2901878503 hasConcept C207103383 @default.
• W2901878503 hasConcept C2778164965 @default.
• W2901878503 hasConcept C2779013556 @default.
• W2901878503 hasConcept C2779343474 @default.
• W2901878503 hasConcept C2780387249 @default.
• W2901878503 hasConcept C2781156865 @default.
• W2901878503 hasConcept C44249647 @default.
• W2901878503 hasConcept C509974204 @default.
• W2901878503 hasConcept C71924100 @default.
• W2901878503 hasConcept C86803240 @default.
• W2901878503 hasConceptScore W2901878503C121608353 @default.
• W2901878503 hasConceptScore W2901878503C126322002 @default.
• W2901878503 hasConceptScore W2901878503C141071460 @default.
• W2901878503 hasConceptScore W2901878503C151730666 @default.
• W2901878503 hasConceptScore W2901878503C207103383 @default.
• W2901878503 hasConceptScore W2901878503C2778164965 @default.
• W2901878503 hasConceptScore W2901878503C2779013556 @default.
• W2901878503 hasConceptScore W2901878503C2779343474 @default.
• W2901878503 hasConceptScore W2901878503C2780387249 @default.
• W2901878503 hasConceptScore W2901878503C2781156865 @default.
• W2901878503 hasConceptScore W2901878503C44249647 @default.
• W2901878503 hasConceptScore W2901878503C509974204 @default.
• W2901878503 hasConceptScore W2901878503C71924100 @default.
• W2901878503 hasConceptScore W2901878503C86803240 @default.

• next