FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2902019439> ?p ?o ?g. }

• W2902019439 abstract "Objectives: Although generalized muscle pain, tiredness, anxiety, and depression are commonly present among chronic widespread pain (CWP) patients, the molecular mechanisms behind CWP are not fully elucidated. Moreover, the lack of biomarkers often makes diagnosis and treatment problematic. In this study, we investigated the correlation between pain intensity, psychological distress, and plasma proteins among CWP patients and controls (CON). Methods: The plasma proteome of CWP (n = 15) and CON (n = 23) was analyzed using two-dimensional gel electrophoresis. Orthogonal Partial Least Square analysis (OPLS) was used to determine proteins associated with pain intensity (numeric rating scale) in CWP and psychological distress (Hospital and Depression Scale, HADS) in CWP and CON. Significant proteins were identified by MALDI-TOF and tandem MS. Results: In CWP, pain intensity was associated with plasma proteins mostly involved in metabolic and immunity processes (e.g., kininogen-1, fibrinogen gamma chain, and ceruloplasmin), and psychological distress was associated with plasma proteins related to immunity response, iron ion, and lipid metabolism (e.g., complement factor B, complement C1r subcomponent, hemopexin, and clusterin). Discussion: This study suggests that different plasma protein patterns are associated with different pain intensity and psychological distress in CWP. Proteins belonging to the coagulation cascade and immunity processes showed strong associations to each clinical outcome. Using the plasma proteome profile of CWP to study potential biomarker candidates provides a snapshot of ongoing systemic mechanisms in CWP." @default.
• W2902019439 created "2018-12-11" @default.
• W2902019439 creator A5048017178 @default.
• W2902019439 creator A5078576085 @default.
• W2902019439 creator A5084884436 @default.
• W2902019439 creator A5088987945 @default.
• W2902019439 date "2018-11-29" @default.
• W2902019439 modified "2023-10-14" @default.
• W2902019439 title "Plasma Protein Pattern Correlates With Pain Intensity and Psychological Distress in Women With Chronic Widespread Pain" @default.
• W2902019439 cites W1440648612 @default.
• W2902019439 cites W1489578051 @default.
• W2902019439 cites W1559704894 @default.
• W2902019439 cites W1587873088 @default.
• W2902019439 cites W1843165317 @default.
• W2902019439 cites W1845447069 @default.
• W2902019439 cites W1891909707 @default.
• W2902019439 cites W1966628524 @default.
• W2902019439 cites W1970835190 @default.
• W2902019439 cites W1971953711 @default.
• W2902019439 cites W1972663012 @default.
• W2902019439 cites W1974040610 @default.
• W2902019439 cites W1980409139 @default.
• W2902019439 cites W1985438873 @default.
• W2902019439 cites W1987138256 @default.
• W2902019439 cites W1987410232 @default.
• W2902019439 cites W1989837855 @default.
• W2902019439 cites W1999082606 @default.
• W2902019439 cites W2003982930 @default.
• W2902019439 cites W2005002021 @default.
• W2902019439 cites W2022682828 @default.
• W2902019439 cites W2031107255 @default.
• W2902019439 cites W2031601626 @default.
• W2902019439 cites W2050718087 @default.
• W2902019439 cites W2060053586 @default.
• W2902019439 cites W2061794524 @default.
• W2902019439 cites W2061843589 @default.
• W2902019439 cites W2063949463 @default.
• W2902019439 cites W2069008691 @default.
• W2902019439 cites W2069137512 @default.
• W2902019439 cites W2074122852 @default.
• W2902019439 cites W2078132464 @default.
• W2902019439 cites W2078678101 @default.
• W2902019439 cites W2079660836 @default.
• W2902019439 cites W2086134310 @default.
• W2902019439 cites W2089944969 @default.
• W2902019439 cites W2100014097 @default.
• W2902019439 cites W2105786999 @default.
• W2902019439 cites W2106417432 @default.
• W2902019439 cites W2128439575 @default.
• W2902019439 cites W2129034456 @default.
• W2902019439 cites W2132309748 @default.
• W2902019439 cites W2134557769 @default.
• W2902019439 cites W2134586420 @default.
• W2902019439 cites W2139516730 @default.
• W2902019439 cites W2148827382 @default.
• W2902019439 cites W2152611039 @default.
• W2902019439 cites W2156685665 @default.
• W2902019439 cites W2159388411 @default.
• W2902019439 cites W2161727260 @default.
• W2902019439 cites W2166281097 @default.
• W2902019439 cites W2167613032 @default.
• W2902019439 cites W2172116519 @default.
• W2902019439 cites W2174721344 @default.
• W2902019439 cites W2178010673 @default.
• W2902019439 cites W2253364553 @default.
• W2902019439 cites W2326319948 @default.
• W2902019439 cites W2336476615 @default.
• W2902019439 cites W2339036884 @default.
• W2902019439 cites W2345707054 @default.
• W2902019439 cites W2346277700 @default.
• W2902019439 cites W2410418764 @default.
• W2902019439 cites W2466185491 @default.
• W2902019439 cites W2518279931 @default.
• W2902019439 cites W2547814918 @default.
• W2902019439 cites W2592360091 @default.
• W2902019439 cites W2593025118 @default.
• W2902019439 cites W2596033074 @default.
• W2902019439 cites W2605189579 @default.
• W2902019439 cites W2613598114 @default.
• W2902019439 cites W2758808222 @default.
• W2902019439 cites W2759363431 @default.
• W2902019439 cites W2765280371 @default.
• W2902019439 cites W2766725617 @default.
• W2902019439 cites W2884829889 @default.
• W2902019439 cites W819018147 @default.
• W2902019439 doi "https://doi.org/10.3389/fpsyg.2018.02400" @default.
• W2902019439 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6281753" @default.
• W2902019439 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30555396" @default.
• W2902019439 hasPublicationYear "2018" @default.
• W2902019439 type Work @default.
• W2902019439 sameAs 2902019439 @default.
• W2902019439 citedByCount "24" @default.
• W2902019439 countsByYear W29020194392019 @default.
• W2902019439 countsByYear W29020194392020 @default.
• W2902019439 countsByYear W29020194392021 @default.
• W2902019439 countsByYear W29020194392022 @default.
• W2902019439 countsByYear W29020194392023 @default.
• W2902019439 crossrefType "journal-article" @default.
• W2902019439 hasAuthorship W2902019439A5048017178 @default.
• W2902019439 hasAuthorship W2902019439A5078576085 @default.

• next