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- W2902050614 abstract "Isatin chalcones and their 3-hydroxy precursors are shown to possess potential anticancer activity and are also versatile substrates and key intermediates for the synthesis of a large variety of bioactive spiro-oxindoles. An environmental friendly tandem synthesis, using PEG 400 as green solvent cum phase transfer catalyst, for a series of 3-hydroxy-2-oxindoles and 3-methylene-2-oxindoles has been developed. Reported one-pot sustainable synthetic strategy was compared with the conventional method and was found to be superior to existing two-step syntheses in terms of simplicity, product yield, and reaction time and have a large substrate scope." @default.
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- W2902050614 date "2018-11-28" @default.
- W2902050614 modified "2023-09-25" @default.
- W2902050614 title "Eco-friendly Polyethylene Glycol-400 as a Rapid and Efficient Recyclable Reaction Medium for the Synthesis of Anticancer Isatin-linked Chalcones and Their 3-Hydroxy Precursor" @default.
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- W2902050614 doi "https://doi.org/10.1002/jhet.3424" @default.
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