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- W2902085560 endingPage "256" @default.
- W2902085560 startingPage "221" @default.
- W2902085560 abstract "Nanomedicine, the application of nanotechnology to treatment and prevention of diseases, is an emerging form of drug therapy that utilizes nanomaterials as drug carriers for enhancing treatment efficacy while reducing detrimental side effects to normal tissues. Nanomaterials, with their size range (1–100 nm) that corresponds to basic biological materials such as DNA and vastly increased surface area, have a wide range of applications from drug and gene delivery to biomedical imaging. The major advantages of using nanomaterials as a carrier for anticancer agents are the possibility of targeted delivery to the tumor, tumor imaging, their ability to hold thousands of molecules of a drug, and also their ability to overcome solubility, stability, and resistance issues. Currently, there are several nanotechnology-enabled diagnostic and therapeutic agents undergoing clinical trials, and a few are already approved by the US Food and Drug Administration (FDA) and European Medicine Agency (EMA). Targeted delivery of anticancer agents is achieved by “Enhanced Permeation and Retention Effect” (EPR effect) and/or active targeting. This review provides an update on FDA-approved cancer nanomedicines and those in nanoplatforms that have reached an advanced stage of clinical development utilizing liposomes, albumin nanospheres, micelles, and gold nanoparticles." @default.
- W2902085560 created "2018-12-11" @default.
- W2902085560 creator A5039964018 @default.
- W2902085560 date "2019-01-01" @default.
- W2902085560 modified "2023-10-14" @default.
- W2902085560 title "Nanotechnology Toward Treating Cancer" @default.
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