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- W2902177978 endingPage "60" @default.
- W2902177978 startingPage "1" @default.
- W2902177978 abstract "To be able to perform their biological function, a protein needs to be correctly folded into its three dimensional structure. The protein folding process is spontaneous and does not require the input of energy. However, in the crowded cellular environment where there is high risk of inter-molecular interactions that may lead to protein molecules sticking to each other, hence forming aggregates, protein folding is assisted. Cells have evolved robust machinery called molecular chaperones to deal with the protein folding problem and to maintain proteins in their functional state. Molecular chaperones promote efficient folding of newly synthesized proteins, prevent their aggregation and ensure protein homeostasis in cells. There are different classes of molecular chaperones functioning in a complex interplay. In this review, we discuss the principal characteristics of different classes of molecular chaperones, their structure-function relationships, their mode of regulation and their involvement in human disorders." @default.
- W2902177978 created "2018-12-11" @default.
- W2902177978 creator A5056532113 @default.
- W2902177978 creator A5074839515 @default.
- W2902177978 date "2019-01-01" @default.
- W2902177978 modified "2023-10-14" @default.
- W2902177978 title "Functional principles and regulation of molecular chaperones" @default.
- W2902177978 cites W116814209 @default.
- W2902177978 cites W1492302030 @default.
- W2902177978 cites W1494494379 @default.
- W2902177978 cites W1519882367 @default.
- W2902177978 cites W1520714027 @default.
- W2902177978 cites W1525028320 @default.
- W2902177978 cites W1537274817 @default.
- W2902177978 cites W1546638544 @default.
- W2902177978 cites W1553413779 @default.
- W2902177978 cites W1554180547 @default.
- W2902177978 cites W1559420025 @default.
- W2902177978 cites W1580261198 @default.
- W2902177978 cites W1583407009 @default.
- W2902177978 cites W1583825507 @default.
- W2902177978 cites W1589193262 @default.
- W2902177978 cites W1602112219 @default.
- W2902177978 cites W1663611608 @default.
- W2902177978 cites W1790977108 @default.
- W2902177978 cites W1797775581 @default.
- W2902177978 cites W1806791563 @default.
- W2902177978 cites W1815807971 @default.
- W2902177978 cites W1835200336 @default.
- W2902177978 cites W1876533241 @default.
- W2902177978 cites W1892996896 @default.
- W2902177978 cites W1898085476 @default.
- W2902177978 cites W1955276614 @default.
- W2902177978 cites W1956379070 @default.
- W2902177978 cites W1963838170 @default.
- W2902177978 cites W1964128878 @default.
- W2902177978 cites W1964298460 @default.
- W2902177978 cites W1964826325 @default.
- W2902177978 cites W1964995688 @default.
- W2902177978 cites W1965038486 @default.
- W2902177978 cites W1965060663 @default.
- W2902177978 cites W1966238197 @default.
- W2902177978 cites W1966760093 @default.
- W2902177978 cites W1967960279 @default.
- W2902177978 cites W1968155837 @default.
- W2902177978 cites W1971063516 @default.
- W2902177978 cites W1971108880 @default.
- W2902177978 cites W1972121275 @default.
- W2902177978 cites W1972299037 @default.
- W2902177978 cites W1973027077 @default.
- W2902177978 cites W1974206962 @default.
- W2902177978 cites W1974793156 @default.
- W2902177978 cites W1974886740 @default.
- W2902177978 cites W1976419927 @default.
- W2902177978 cites W1976488701 @default.
- W2902177978 cites W1977098850 @default.
- W2902177978 cites W1978014671 @default.
- W2902177978 cites W1978440190 @default.
- W2902177978 cites W1978490927 @default.
- W2902177978 cites W1980449331 @default.
- W2902177978 cites W1980505864 @default.
- W2902177978 cites W1980627844 @default.
- W2902177978 cites W1980786000 @default.
- W2902177978 cites W1981256745 @default.
- W2902177978 cites W1982079790 @default.
- W2902177978 cites W1982177408 @default.
- W2902177978 cites W1982408965 @default.
- W2902177978 cites W1982580121 @default.
- W2902177978 cites W1982715618 @default.
- W2902177978 cites W1983665072 @default.
- W2902177978 cites W1983705778 @default.
- W2902177978 cites W1984831405 @default.
- W2902177978 cites W1985408089 @default.
- W2902177978 cites W1987220770 @default.
- W2902177978 cites W1989999739 @default.
- W2902177978 cites W1990058209 @default.
- W2902177978 cites W1991292950 @default.
- W2902177978 cites W1991498388 @default.
- W2902177978 cites W1992690825 @default.
- W2902177978 cites W1993050837 @default.
- W2902177978 cites W1993466444 @default.
- W2902177978 cites W1994485012 @default.
- W2902177978 cites W1995210988 @default.
- W2902177978 cites W1995792761 @default.
- W2902177978 cites W1996645786 @default.
- W2902177978 cites W1997088693 @default.
- W2902177978 cites W1997198762 @default.
- W2902177978 cites W1997659862 @default.
- W2902177978 cites W1997718936 @default.
- W2902177978 cites W1998134951 @default.
- W2902177978 cites W1998425418 @default.
- W2902177978 cites W1998753889 @default.
- W2902177978 cites W1998960610 @default.
- W2902177978 cites W1999268424 @default.
- W2902177978 cites W1999465079 @default.
- W2902177978 cites W1999819298 @default.
- W2902177978 cites W2002308733 @default.
- W2902177978 cites W2002364392 @default.