Matches in SemOpenAlex for { <https://semopenalex.org/work/W2902210080> ?p ?o ?g. }
- W2902210080 abstract "Abstract Mercury is considered to be “a global pollutant” and raises concern worldwide. Once mercury enters the body, it will be distributed all over the body but will accumulate in the brain, kidney and liver. To date, no substance originating from edible fungi capable of adsorbing mercury has been reported. We found that the mushroom Grifola frondosa exhibited mercury adsorption capacity. A polysaccharide-peptide (GFPP), displaying the unique N-terminal amino acid sequence of APPGMHQKQQ and 7 partial sequences with high reliability obtained by LC-MS/MS, was isolated by hot-water extraction of its fruiting bodies followed by ion exchange chromatography and gel filtration chromatography. Two rat models were employed to determine the dose and the duration of HgCl 2 treatment (given by acute administration or continuous treatment) to test if G. frondosa could promote mercury elimination. For rats subjected to acute treatment with HgCl 2 , both GFPP and G. frondosa fruiting bodies (GFFF) could accelerate the decline of blood mercury level, which fell precipitously by 50% on the second day. GFPP and GFFF also promoted elimination of the burden of mercury in the liver and kidneys. For rats receiving continuous HgCl 2 treatment, G. frondosa prevented the progressive increase of blood mercury level, and kept the blood mercury level within a relatively stable range." @default.
- W2902210080 created "2018-12-11" @default.
- W2902210080 creator A5004229722 @default.
- W2902210080 creator A5006590841 @default.
- W2902210080 creator A5035780833 @default.
- W2902210080 creator A5045714439 @default.
- W2902210080 creator A5060795142 @default.
- W2902210080 creator A5067771631 @default.
- W2902210080 creator A5078495521 @default.
- W2902210080 date "2018-12-04" @default.
- W2902210080 modified "2023-10-14" @default.
- W2902210080 title "A polysaccharide-peptide with mercury clearance activity from dried fruiting bodies of maitake mushroom Grifola frondosa" @default.
- W2902210080 cites W130884863 @default.
- W2902210080 cites W1504737472 @default.
- W2902210080 cites W151229572 @default.
- W2902210080 cites W1950756257 @default.
- W2902210080 cites W1977278052 @default.
- W2902210080 cites W1980620688 @default.
- W2902210080 cites W1981592715 @default.
- W2902210080 cites W1989198338 @default.
- W2902210080 cites W2001237913 @default.
- W2902210080 cites W2023946535 @default.
- W2902210080 cites W2034834439 @default.
- W2902210080 cites W2038794253 @default.
- W2902210080 cites W2043463869 @default.
- W2902210080 cites W2050264600 @default.
- W2902210080 cites W2050632512 @default.
- W2902210080 cites W2053283983 @default.
- W2902210080 cites W2059104038 @default.
- W2902210080 cites W2069011642 @default.
- W2902210080 cites W2069251742 @default.
- W2902210080 cites W2070338672 @default.
- W2902210080 cites W2070740498 @default.
- W2902210080 cites W2073605547 @default.
- W2902210080 cites W2084092687 @default.
- W2902210080 cites W2089990836 @default.
- W2902210080 cites W2093536322 @default.
- W2902210080 cites W2106206681 @default.
- W2902210080 cites W2108068235 @default.
- W2902210080 cites W2133579959 @default.
- W2902210080 cites W2133748479 @default.
- W2902210080 cites W2135333143 @default.
- W2902210080 cites W2154868436 @default.
- W2902210080 cites W2162698767 @default.
- W2902210080 cites W2163125062 @default.
- W2902210080 cites W2188241773 @default.
- W2902210080 cites W2318485526 @default.
- W2902210080 cites W2461653735 @default.
- W2902210080 cites W2467932622 @default.
- W2902210080 cites W2556630670 @default.
- W2902210080 cites W2559950339 @default.
- W2902210080 cites W2605851091 @default.
- W2902210080 cites W2740977101 @default.
- W2902210080 cites W2754211114 @default.
- W2902210080 cites W2756416645 @default.
- W2902210080 cites W2771985027 @default.
- W2902210080 cites W2775376342 @default.
- W2902210080 cites W3197115640 @default.
- W2902210080 cites W2120938158 @default.
- W2902210080 doi "https://doi.org/10.1038/s41598-018-35945-9" @default.
- W2902210080 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6279823" @default.
- W2902210080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30514871" @default.
- W2902210080 hasPublicationYear "2018" @default.
- W2902210080 type Work @default.
- W2902210080 sameAs 2902210080 @default.
- W2902210080 citedByCount "8" @default.
- W2902210080 countsByYear W29022100802019 @default.
- W2902210080 countsByYear W29022100802021 @default.
- W2902210080 countsByYear W29022100802022 @default.
- W2902210080 countsByYear W29022100802023 @default.
- W2902210080 crossrefType "journal-article" @default.
- W2902210080 hasAuthorship W2902210080A5004229722 @default.
- W2902210080 hasAuthorship W2902210080A5006590841 @default.
- W2902210080 hasAuthorship W2902210080A5035780833 @default.
- W2902210080 hasAuthorship W2902210080A5045714439 @default.
- W2902210080 hasAuthorship W2902210080A5060795142 @default.
- W2902210080 hasAuthorship W2902210080A5067771631 @default.
- W2902210080 hasAuthorship W2902210080A5078495521 @default.
- W2902210080 hasBestOaLocation W29022100801 @default.
- W2902210080 hasConcept C100817775 @default.
- W2902210080 hasConcept C107872376 @default.
- W2902210080 hasConcept C185592680 @default.
- W2902210080 hasConcept C199360897 @default.
- W2902210080 hasConcept C2776474821 @default.
- W2902210080 hasConcept C2777777548 @default.
- W2902210080 hasConcept C2780208070 @default.
- W2902210080 hasConcept C2780638308 @default.
- W2902210080 hasConcept C31903555 @default.
- W2902210080 hasConcept C41008148 @default.
- W2902210080 hasConcept C43617362 @default.
- W2902210080 hasConcept C55493867 @default.
- W2902210080 hasConceptScore W2902210080C100817775 @default.
- W2902210080 hasConceptScore W2902210080C107872376 @default.
- W2902210080 hasConceptScore W2902210080C185592680 @default.
- W2902210080 hasConceptScore W2902210080C199360897 @default.
- W2902210080 hasConceptScore W2902210080C2776474821 @default.
- W2902210080 hasConceptScore W2902210080C2777777548 @default.
- W2902210080 hasConceptScore W2902210080C2780208070 @default.
- W2902210080 hasConceptScore W2902210080C2780638308 @default.
- W2902210080 hasConceptScore W2902210080C31903555 @default.