Matches in SemOpenAlex for { <https://semopenalex.org/work/W2902372455> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2902372455 endingPage "S15" @default.
- W2902372455 startingPage "S15.2" @default.
- W2902372455 abstract "The topic of behavioral and structural deficits caused by concussions is an increasingly important 1 in the related research fields. With an incidence rate of 2.9 competition concussions per 1,000 athlete exposures (NCAA 2013) in collegiate football, the concussion risk to athletes is significant. However, even subconcussive blows, or blows that do not lead to a concussion diagnosis, appear to create health risks for athletes. These impacts appear to lead to significant neural changes, the severity of which may depend on the number of hits (McAllister et al., 2014). An anatomically informed, personalized-medicine tractography approach was used to determine which major white matter tracts showed the greatest degree of difference in white matter tensor measures between 17 Division I upperclassmen football players, 15 Division I upperclassman cross-country runners, and 9 socioeconomically-matched non-athlete controls. We determined the underlying microstructural white matter biomarkers, using a classic diffusion-tensor model (Pierpaoli and Basser, 1999) as well as Neurite Orientation Dispersion and Density Imaging (NODDI; Zhang et al., 2012), that predict differences across different white matter tracts in the groups of athletes. Results show widespread differences in white matter tissue properties in multiple tracts and among the 3 athletes groups, including decreased FA, increased ICVF, and OD in the football players vs the 2 control groups. These differences occurred more often in longer fiber tracts compared to shorter fiber tracts, suggesting a differential effect of head impacts based on the geometric properties of these tracts. We developed a fully automated processing pipeline for this study, available as open source code as well as open service at brainlife.io. These results support the hypothesis that multiple subconcussive blows can result in white matter structural changes, with differential effects based on the length of the fiber tract being investigated, that are detectable with diffusion MRI and tractography." @default.
- W2902372455 created "2018-12-11" @default.
- W2902372455 creator A5044444127 @default.
- W2902372455 creator A5070135653 @default.
- W2902372455 creator A5076230258 @default.
- W2902372455 date "2018-12-04" @default.
- W2902372455 modified "2023-09-25" @default.
- W2902372455 title "Advanced white matter mapping in the subconcussive brain" @default.
- W2902372455 doi "https://doi.org/10.1212/01.wnl.0000550693.00184.ee" @default.
- W2902372455 hasPublicationYear "2018" @default.
- W2902372455 type Work @default.
- W2902372455 sameAs 2902372455 @default.
- W2902372455 citedByCount "0" @default.
- W2902372455 crossrefType "journal-article" @default.
- W2902372455 hasAuthorship W2902372455A5044444127 @default.
- W2902372455 hasAuthorship W2902372455A5070135653 @default.
- W2902372455 hasAuthorship W2902372455A5076230258 @default.
- W2902372455 hasBestOaLocation W29023724551 @default.
- W2902372455 hasConcept C126838900 @default.
- W2902372455 hasConcept C143409427 @default.
- W2902372455 hasConcept C149550507 @default.
- W2902372455 hasConcept C15744967 @default.
- W2902372455 hasConcept C166957645 @default.
- W2902372455 hasConcept C1862650 @default.
- W2902372455 hasConcept C190385971 @default.
- W2902372455 hasConcept C205649164 @default.
- W2902372455 hasConcept C2778426673 @default.
- W2902372455 hasConcept C2778444522 @default.
- W2902372455 hasConcept C2781054738 @default.
- W2902372455 hasConcept C2781192897 @default.
- W2902372455 hasConcept C3017944768 @default.
- W2902372455 hasConcept C3020114046 @default.
- W2902372455 hasConcept C71924100 @default.
- W2902372455 hasConcept C99454951 @default.
- W2902372455 hasConcept C99508421 @default.
- W2902372455 hasConceptScore W2902372455C126838900 @default.
- W2902372455 hasConceptScore W2902372455C143409427 @default.
- W2902372455 hasConceptScore W2902372455C149550507 @default.
- W2902372455 hasConceptScore W2902372455C15744967 @default.
- W2902372455 hasConceptScore W2902372455C166957645 @default.
- W2902372455 hasConceptScore W2902372455C1862650 @default.
- W2902372455 hasConceptScore W2902372455C190385971 @default.
- W2902372455 hasConceptScore W2902372455C205649164 @default.
- W2902372455 hasConceptScore W2902372455C2778426673 @default.
- W2902372455 hasConceptScore W2902372455C2778444522 @default.
- W2902372455 hasConceptScore W2902372455C2781054738 @default.
- W2902372455 hasConceptScore W2902372455C2781192897 @default.
- W2902372455 hasConceptScore W2902372455C3017944768 @default.
- W2902372455 hasConceptScore W2902372455C3020114046 @default.
- W2902372455 hasConceptScore W2902372455C71924100 @default.
- W2902372455 hasConceptScore W2902372455C99454951 @default.
- W2902372455 hasConceptScore W2902372455C99508421 @default.
- W2902372455 hasIssue "23 Supplement 1" @default.
- W2902372455 hasLocation W29023724551 @default.
- W2902372455 hasOpenAccess W2902372455 @default.
- W2902372455 hasPrimaryLocation W29023724551 @default.
- W2902372455 hasRelatedWork W157521275 @default.
- W2902372455 hasRelatedWork W1617802654 @default.
- W2902372455 hasRelatedWork W2018468298 @default.
- W2902372455 hasRelatedWork W2306834340 @default.
- W2902372455 hasRelatedWork W2899534825 @default.
- W2902372455 hasRelatedWork W2902372455 @default.
- W2902372455 hasRelatedWork W3016225345 @default.
- W2902372455 hasRelatedWork W3041726547 @default.
- W2902372455 hasRelatedWork W3132698092 @default.
- W2902372455 hasRelatedWork W4223430515 @default.
- W2902372455 hasVolume "91" @default.
- W2902372455 isParatext "false" @default.
- W2902372455 isRetracted "false" @default.
- W2902372455 magId "2902372455" @default.
- W2902372455 workType "article" @default.