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• W2902435611 abstract "The epidemiologic study of DNA methylation (DNAm) and mental health is a burgeoning area, but confounding and reverse causation remain important to know about. Whether use of non-brain tissues is appropriate when investigating brain phenotypes depends on the hypothesis and whether the goal is causality or to identify biomarkers. Look-ups of the correspondence between DNAm in blood and brain and use of Mendelian randomization (MR) can be done to follow-up, to some degree, on the causal nature of some findings. Social scientists, health methodologists (epidemiologists), and basic scientists — thinkers who view epigenetics and mental health from different perspectives — can come together in the design and framing of findings to avoid pitfalls and innovate beyond what each could do alone." @default.
• W2902435611 created "2018-12-11" @default.
• W2902435611 creator A5073472643 @default.
• W2902435611 date "2019-06-01" @default.
• W2902435611 modified "2023-09-25" @default.
• W2902435611 title "A brief tour of epidemiologic epigenetics and mental health" @default.
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• W2902435611 doi "https://doi.org/10.1016/j.copsyc.2018.07.010" @default.
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