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- W2902805963 abstract "The temperature dependence of proton's spin-lattice relaxation time T1 in water samples and Gd-based contrast agents with a measurement field of 72 μT was systematically studied by dc-SQUID-based ultralow field (ULF) nuclear magnetic resonance (NMR) spectrometer. The temperature of samples was controlled by a thermostatic bath and the standard error of T1 was around 0.01 s within five different groups, the results showed that T1 had a similar linear temperature dependence when it was compared to conventional NMR data and varied with the purity of the water samples. Then, the relaxivity r1 of Gd-based metal-organic frameworks (MOFs) and Gd-DTPA (where DTPA is diethylene triamine pentaacetate) were also studied. Both of them had a much higher r1 in ULF NMR than conventional NMR, which was around 45 mM <sup xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>-1</sup> ·s <sup xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>-1</sup> and 98 mM <sup xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>-1</sup> ·s <sup xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>-1</sup> , respectively; however, the T1 of Gd-based contrast agents did not follow the linear temperature dependence, and the relaxivity r1 would not be influenced by temperature, which implies Gd-MOFs and Gd-DTPA are also high performance T 1 contrast agents in ULF NMR and MRI." @default.
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- W2902805963 date "2019-06-01" @default.
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- W2902805963 title "Investigations of the <italic>T</italic>1 Temperature Dependence of Protons in Water and Contrast Agents Using a High-<italic>T</italic>c DC-SQUID-Based ULF NMR System" @default.
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