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- W2902902034 abstract "Amaç: Bu çalışmanın amacı, vücut kitle indeksi (VKİ) kriterlerine göre normal ağırlıktan morbid obeze kadar gruplandırılan erişkin erkek ve kadın kohortunda grelin hormonunun VKİ, serum lipitleri ve C-reaktif protein (CRP) ile ilişkisini değerlendirmektir. Gereç ve Yöntem: Isparta Gülkent Devlet Hastanesi Göğüs Hastalıkları Uyku Laboratuarı ve Süleyman Demirel Üniversitesi Tıp Fakültesi Uyku Hastalıkları Merkezine başvuran 20-59 yaş arası toplam iki yüz altmış erkek (n = 151) ve kadın (n = 109) çalışmaya dahil edildi. Toplam grelin, CRP, serum lipitleri ve glukoz seviyeleri gece açlığından sonra ölçüldü. Bulgular: Grelin düzeyleri obez olgularda istatistiksel olarak anlamlı derecede düşük bulundu (P <0.001), Glikoz düzeyleri obez olgularda klinik olarak daha yüksekti ancak istatistiksel olarak anlamlı değildi. Açlık plazma grelin, VKİ, kolesterol, trigliserid ve CRP ile negatif korelasyonlar gösterdi (sırasıyla, r = -0.402, P <0.01; 0,259, p = 0,01; 0,137, p = 0,05; r = 0,146, p = 0,05). Grelin ve glukoz arasında zayıf anlamlı korelasyon vardı (r = 0,131, p = 0,05). Sonuç: Obez bireylerin grelin düzeylerinin düşük olması glikoz, CRP, kolesterol, trigliserid ve vücut kitle indeksi ile anlamlı derecede ilişkilidir. Grelinin insan obezitesinin patogenezindeki rolünü belirlemek için daha ileriye dönük çalışmalara ihtiyaç vardır." @default.
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- W2902902034 date "2019-06-01" @default.
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- W2902902034 title "FASTING SERUM GHRELIN LEVELS IS NEGATIVELY ASSOCIATED WITH BODY MASS INDEX, CHOLESTEROL, TRIGLYCERIDE AND C-REACTIVE PROTEIN" @default.
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