Matches in SemOpenAlex for { <https://semopenalex.org/work/W2902904767> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2902904767 abstract "To evaluate the correlation between subrogate index for the evaluation of insulin resistance with the M value obtained with the euglycemic-hyperinsulinemic clamp as well as their sensitivity, specificity, and positive and negative predictive values.The euglycemic-hyperinsulinemic clamp was performed in subjects having both normal fasting glucose and glycated hemoglobin concentrations. HOMA-IR, QUICKI, HOMA2%S, TyG, TyG*body mass index (BMI) and triglyceride/HDL indexes were calculated. Correlations coefficients were estimated between indexes results and the M-value adjusted by fat-free mass. Areas under the ROC curve were constructed to evaluate overall performance, sensitivity, specificity and predictive values of the subrogate indexes.57 subjects, 68.4% women, with a mean age of 32.9 ± 11 years-old were included. The subrogate index with the best correlation with the M value was HOMA2%S (r = 0.428), HOMA-IR had the greatest area under the ROC curve (0.683; 95 % confidence interval: 0.503-0.864) and TyG*BMI the best sensitivity (98.2 %) and specificity (51.1 %).The surrogated indexes for the evaluation of insulin resistance show a significant correlation with the M value obtained with the gold standard. Additional studies are required to determine cut-off values in Mexican population.Evaluar la correlación entre índices subrogados de resistencia a la insulina y el valor M obtenido mediante pinza euglucémica-hiperinsulinémica, así como su sensibilidad, especificidad y valores predictivos positivo y negativo, en mexicanos sin diabetes.Se realizó una pinza euglucémica-hiperinsulinémica en individuos con glucosa en ayuno y hemoglobina glucosilada normales. Se estimaron los índices HOMA-IR, QUICKI, HOMA2%S, TyG, TyG*índice de masa corporal (IMC) y triglicéridos/colesterol ligado a lipoproteínas de alta densidad. Se estimaron coeficientes de correlación de Pearson entre los resultados y el valor M ajustado por masa libre de grasa. Se construyeron curvas ROC para evaluar su desempeño y se estimaron la sensibilidad, la especificidad y los valores predictivos de los índices.Se incluyeron 57 individuos, el 68.4 % mujeres, de 32.9 ± 11 años, con IMC de 26.5 ± 3.9 kg/m2. El índice subrogado con mejor correlación con el valor M fue HOMA2%S (r = 0.428), con la mayor área bajo la curva ROC (0.683; intervalo de confianza del 95 %: 0.503-0.864) HOMA-IR, y con mejor sensibilidad (92.8 %) y especificidad (51.1 %) TyG*IMC.Los índices subrogados para estimar la resistencia a la insulina muestran una correlación significativa con el valor M obtenido con el método de referencia. Se requieren más estudios para determinar puntos de corte en población mexicana." @default.
- W2902904767 created "2018-12-11" @default.
- W2902904767 creator A5005019504 @default.
- W2902904767 creator A5036669854 @default.
- W2902904767 creator A5047616746 @default.
- W2902904767 creator A5054077929 @default.
- W2902904767 creator A5066156346 @default.
- W2902904767 creator A5082237231 @default.
- W2902904767 creator A5088249067 @default.
- W2902904767 date "2018-10-01" @default.
- W2902904767 modified "2023-10-01" @default.
- W2902904767 title "Índices para la evaluación de la resistencia a la insulina en individuos mexicanos sin diabetes" @default.
- W2902904767 doi "https://doi.org/10.24875/gmm.18004578" @default.
- W2902904767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30532124" @default.
- W2902904767 hasPublicationYear "2018" @default.
- W2902904767 type Work @default.
- W2902904767 sameAs 2902904767 @default.
- W2902904767 citedByCount "5" @default.
- W2902904767 countsByYear W29029047672020 @default.
- W2902904767 countsByYear W29029047672021 @default.
- W2902904767 countsByYear W29029047672022 @default.
- W2902904767 countsByYear W29029047672023 @default.
- W2902904767 crossrefType "journal-article" @default.
- W2902904767 hasAuthorship W2902904767A5005019504 @default.
- W2902904767 hasAuthorship W2902904767A5036669854 @default.
- W2902904767 hasAuthorship W2902904767A5047616746 @default.
- W2902904767 hasAuthorship W2902904767A5054077929 @default.
- W2902904767 hasAuthorship W2902904767A5066156346 @default.
- W2902904767 hasAuthorship W2902904767A5082237231 @default.
- W2902904767 hasAuthorship W2902904767A5088249067 @default.
- W2902904767 hasBestOaLocation W29029047671 @default.
- W2902904767 hasConcept C126322002 @default.
- W2902904767 hasConcept C134018914 @default.
- W2902904767 hasConcept C2777180221 @default.
- W2902904767 hasConcept C2777391703 @default.
- W2902904767 hasConcept C2777538456 @default.
- W2902904767 hasConcept C2778163477 @default.
- W2902904767 hasConcept C2778913445 @default.
- W2902904767 hasConcept C2779306644 @default.
- W2902904767 hasConcept C2780221984 @default.
- W2902904767 hasConcept C2908647359 @default.
- W2902904767 hasConcept C40993552 @default.
- W2902904767 hasConcept C44249647 @default.
- W2902904767 hasConcept C555293320 @default.
- W2902904767 hasConcept C58471807 @default.
- W2902904767 hasConcept C71924100 @default.
- W2902904767 hasConcept C99454951 @default.
- W2902904767 hasConceptScore W2902904767C126322002 @default.
- W2902904767 hasConceptScore W2902904767C134018914 @default.
- W2902904767 hasConceptScore W2902904767C2777180221 @default.
- W2902904767 hasConceptScore W2902904767C2777391703 @default.
- W2902904767 hasConceptScore W2902904767C2777538456 @default.
- W2902904767 hasConceptScore W2902904767C2778163477 @default.
- W2902904767 hasConceptScore W2902904767C2778913445 @default.
- W2902904767 hasConceptScore W2902904767C2779306644 @default.
- W2902904767 hasConceptScore W2902904767C2780221984 @default.
- W2902904767 hasConceptScore W2902904767C2908647359 @default.
- W2902904767 hasConceptScore W2902904767C40993552 @default.
- W2902904767 hasConceptScore W2902904767C44249647 @default.
- W2902904767 hasConceptScore W2902904767C555293320 @default.
- W2902904767 hasConceptScore W2902904767C58471807 @default.
- W2902904767 hasConceptScore W2902904767C71924100 @default.
- W2902904767 hasConceptScore W2902904767C99454951 @default.
- W2902904767 hasIssue "92" @default.
- W2902904767 hasLocation W29029047671 @default.
- W2902904767 hasLocation W29029047672 @default.
- W2902904767 hasOpenAccess W2902904767 @default.
- W2902904767 hasPrimaryLocation W29029047671 @default.
- W2902904767 hasRelatedWork W1894700821 @default.
- W2902904767 hasRelatedWork W1980163360 @default.
- W2902904767 hasRelatedWork W2088408940 @default.
- W2902904767 hasRelatedWork W2111784701 @default.
- W2902904767 hasRelatedWork W2118847300 @default.
- W2902904767 hasRelatedWork W2354740885 @default.
- W2902904767 hasRelatedWork W2355104760 @default.
- W2902904767 hasRelatedWork W2374177200 @default.
- W2902904767 hasRelatedWork W2979267474 @default.
- W2902904767 hasRelatedWork W3029936492 @default.
- W2902904767 hasVolume "154" @default.
- W2902904767 isParatext "false" @default.
- W2902904767 isRetracted "false" @default.
- W2902904767 magId "2902904767" @default.
- W2902904767 workType "article" @default.