FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2903076000> ?p ?o ?g. }

• W2903076000 abstract "Abstract Background β-Lactams remain the gold standard for treatment of MSSA bacteremia due to superior outcomes compared with vancomycin. Approximately nine in 10 patients receiving penicillin skin testing (PST) will be de-labeled of a penicillin allergy and able to receive a β-lactam antibiotic. The study aims to evaluate the cost-effectiveness of penicillin allergy confirmation during acute care admission for methicillin-sensitive staphylococcus aureus (MSSA) bacteremia through a PST service. Methods A decision tree analysis was used to compare a PST intervention in patients with a registeredpenicillin allergy during an inpatient admission for MSSA bacteremia vs. usual care (No PST). The model was created from the health sector perspective with a 1-year time horizon. Patients with a penicillin allergy label were expected to receive vancomycin while patients with no penicillin allergy were expected to receive cefazolin. Potential inpatient, outpatient, and adverse reaction costs were considered in all arms of the model. The effects were measured in quality adjusted life years (QALY) and were calculated for patients who were cured, hospitalized, experienced severe adverse events, or died from MSSA infection. Results Patients who received PST services had a mean yearly cost of $12,802, mean quality adjusted life years (QALY) of 0.70, and mean cost/QALY of $18,311. The comparator group not receiving PST services had a mean yearly cost of $12,264, mean quality adjusted life years (QALY) of 0.64, and mean cost/QALY of $19,192. The model produced a final base case ICERof $8,966/QALY for receiving a PST during a hospital admission for the treatment of methicillin-sensitive staphylococcus aureus (MSSA) bacteremia. Conclusion Penicillin allergy confirmation through PST services was cost-effective for patients with a reported penicillin allergy admitted for MSSA bacteremia. Additional research to determine potential benefits of PST services beyond one year could further improve the cost-effectiveness of this intervention. Disclosures S. Meninger, ALK-Abelló: Grant Investigator, Research grant. E. Heil, ALK-Abelló: Grant Investigator, Research grant. T. J. Mattingly II, ALK-Abelló: Grant Investigator, Research grant." @default.
• W2903076000 created "2018-12-11" @default.
• W2903076000 creator A5036700991 @default.
• W2903076000 creator A5069663544 @default.
• W2903076000 creator A5077239022 @default.
• W2903076000 date "2018-11-01" @default.
• W2903076000 modified "2023-10-14" @default.
• W2903076000 title "1216. Cost-Effectiveness of Penicillin Skin Allergy Testing in Methicillin-Sensitive Staphylococcus aureus (MSSA) Bacteremia" @default.
• W2903076000 doi "https://doi.org/10.1093/ofid/ofy210.1049" @default.
• W2903076000 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6252935" @default.
• W2903076000 hasPublicationYear "2018" @default.
• W2903076000 type Work @default.
• W2903076000 sameAs 2903076000 @default.
• W2903076000 citedByCount "0" @default.
• W2903076000 crossrefType "journal-article" @default.
• W2903076000 hasAuthorship W2903076000A5036700991 @default.
• W2903076000 hasAuthorship W2903076000A5069663544 @default.
• W2903076000 hasAuthorship W2903076000A5077239022 @default.
• W2903076000 hasBestOaLocation W29030760001 @default.
• W2903076000 hasConcept C126322002 @default.
• W2903076000 hasConcept C174802600 @default.
• W2903076000 hasConcept C187212893 @default.
• W2903076000 hasConcept C2778353156 @default.
• W2903076000 hasConcept C2778980435 @default.
• W2903076000 hasConcept C2779443120 @default.
• W2903076000 hasConcept C2779489039 @default.
• W2903076000 hasConcept C2910117706 @default.
• W2903076000 hasConcept C501593827 @default.
• W2903076000 hasConcept C523546767 @default.
• W2903076000 hasConcept C54355233 @default.
• W2903076000 hasConcept C71924100 @default.
• W2903076000 hasConcept C86803240 @default.
• W2903076000 hasConcept C89423630 @default.
• W2903076000 hasConceptScore W2903076000C126322002 @default.
• W2903076000 hasConceptScore W2903076000C174802600 @default.
• W2903076000 hasConceptScore W2903076000C187212893 @default.
• W2903076000 hasConceptScore W2903076000C2778353156 @default.
• W2903076000 hasConceptScore W2903076000C2778980435 @default.
• W2903076000 hasConceptScore W2903076000C2779443120 @default.
• W2903076000 hasConceptScore W2903076000C2779489039 @default.
• W2903076000 hasConceptScore W2903076000C2910117706 @default.
• W2903076000 hasConceptScore W2903076000C501593827 @default.
• W2903076000 hasConceptScore W2903076000C523546767 @default.
• W2903076000 hasConceptScore W2903076000C54355233 @default.
• W2903076000 hasConceptScore W2903076000C71924100 @default.
• W2903076000 hasConceptScore W2903076000C86803240 @default.
• W2903076000 hasConceptScore W2903076000C89423630 @default.
• W2903076000 hasLocation W29030760001 @default.
• W2903076000 hasLocation W29030760002 @default.
• W2903076000 hasLocation W29030760003 @default.
• W2903076000 hasOpenAccess W2903076000 @default.
• W2903076000 hasPrimaryLocation W29030760001 @default.
• W2903076000 hasRelatedWork W160702123 @default.
• W2903076000 hasRelatedWork W2030404200 @default.
• W2903076000 hasRelatedWork W2112729164 @default.
• W2903076000 hasRelatedWork W2124366046 @default.
• W2903076000 hasRelatedWork W2132526039 @default.
• W2903076000 hasRelatedWork W2135317088 @default.
• W2903076000 hasRelatedWork W2144130300 @default.
• W2903076000 hasRelatedWork W2903076000 @default.
• W2903076000 hasRelatedWork W3025194846 @default.
• W2903076000 hasRelatedWork W309990249 @default.
• W2903076000 isParatext "false" @default.
• W2903076000 isRetracted "false" @default.
• W2903076000 magId "2903076000" @default.
• W2903076000 workType "article" @default.