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- W2903202346 abstract "Background: Spinal cord injury (SCI) following TEVAR is a devastating complication. Transcranial Magnetic Stimulation (TMS) is a simple, safe and painless alternative to electrical neuromonitoring of the spinal cord and could be used post-operatively. The study aim was to determine the reliability of TMS motor evoked potentials (MEPs) in peripheral vascular disease (PVD) patients. The data is essential for the development of a late SCI TMS management protocol. Methods: 20 healthy controls (mean(±SD) age 28±7.7yrs) and 6 PVD patients (59±14.5yrs, mean VascuQol 4.0) were recruited. Twelve TMS stimuli were given every 10 minutes for one hour. MEPs were measured from two upper limb (left brachioradialis (LBR), abductor pollicis brevis (LAPB)) and three lower limb muscles (left vastus lateralis (LVL), tibialis anterior (LTA), adductor hallucis (LAH)). MEP amplitude, latency and variability were calculated and compared using one-way ANOVA. Results: MEP amplitudes in controls were not, in general, significantly different from those in patients, except for those in LBR - 0.42 vs 0.26mV (control vs patient) (p=0.04); LAPB - 1.91 vs 0.48mV, LVL - 0.31 vs 0.21mV, LTA - 0.67 vs 0.52mV, LAH - 1.07 vs 0.94mV (p>0.05). There were no differences in MEP latencies and variability; a combined muscles coefficient of variation was 0.29 vs 0.44 (p=0.06). Conclusion: The preliminary data show TMS-induced MEPs appear similar in size, latency and variability in healthy subjects and PVD patients, although data collection is ongoing. They provide evidence that TMS may be a reliable tool with which to monitor for SCI development following TEVAR." @default.
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- W2903202346 date "2018-12-01" @default.
- W2903202346 modified "2023-09-27" @default.
- W2903202346 title "Can Transcranial Magnetic Stimulation be used to detect potential spinal cord injury following thoracic endovascular aortic repair (TEVAR)? A preliminary study to characterise baseline motor evoked potentials in vascular disease patients" @default.
- W2903202346 doi "https://doi.org/10.1016/j.ejvs.2018.08.025" @default.
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