Matches in SemOpenAlex for { <https://semopenalex.org/work/W2903586573> ?p ?o ?g. }
- W2903586573 abstract "Abstract Mitochondrial DNA hyperdiversity is primarily caused by high mutation rates ( µ ) and has potential implications for mitogenome architecture and evolution. In the hyperdiverse mtDNA of Melarhaphe neritoides (Gastropoda: Littorinidae), high mutational pressure generates unusually large amounts of synonymous variation, which is expected to (1) promote changes in synonymous codon usage, (2) reflect selection at synonymous sites, (3) increase mtDNA recombination and gene rearrangement, and (4) be correlated with high mtDNA substitution rates. The mitogenome of M. neritoides was sequenced, compared to closely related littorinids and put in the phylogenetic context of Caenogastropoda, to assess the influence of mtDNA hyperdiversity and high µ on gene content and gene order. Most mitogenome features are in line with the trend in Mollusca, except for the atypical secondary structure of the methionine transfer RNA lacking the TΨC-loop. Therefore, mtDNA hyperdiversity and high µ in M. neritoides do not seem to affect its mitogenome architecture. Synonymous sites are under positive selection, which adds to the growing evidence of non-neutral evolution at synonymous sites. Under such non-neutrality, substitution rate involves neutral and non-neutral substitutions, and high µ is not necessarily associated with high substitution rate, thus explaining that, unlike high µ , a high substitution rate is associated with gene order rearrangement." @default.
- W2903586573 created "2018-12-22" @default.
- W2903586573 creator A5025434893 @default.
- W2903586573 creator A5039569420 @default.
- W2903586573 creator A5061765851 @default.
- W2903586573 date "2018-12-19" @default.
- W2903586573 modified "2023-09-26" @default.
- W2903586573 title "Relation between mitochondrial DNA hyperdiversity, mutation rate and mitochondrial genome evolution in Melarhaphe neritoides (Gastropoda: Littorinidae) and other Caenogastropoda" @default.
- W2903586573 cites W153524845 @default.
- W2903586573 cites W1557992090 @default.
- W2903586573 cites W1810556313 @default.
- W2903586573 cites W1843008321 @default.
- W2903586573 cites W1899970138 @default.
- W2903586573 cites W1926293196 @default.
- W2903586573 cites W1969262965 @default.
- W2903586573 cites W1969541700 @default.
- W2903586573 cites W1989083100 @default.
- W2903586573 cites W2020175823 @default.
- W2903586573 cites W2020759799 @default.
- W2903586573 cites W2029226703 @default.
- W2903586573 cites W2035225116 @default.
- W2903586573 cites W2042120426 @default.
- W2903586573 cites W2053231139 @default.
- W2903586573 cites W2060157029 @default.
- W2903586573 cites W2065308805 @default.
- W2903586573 cites W2065831499 @default.
- W2903586573 cites W2074368539 @default.
- W2903586573 cites W2077005155 @default.
- W2903586573 cites W2077283682 @default.
- W2903586573 cites W2087051730 @default.
- W2903586573 cites W2092613863 @default.
- W2903586573 cites W2093016244 @default.
- W2903586573 cites W2099388167 @default.
- W2903586573 cites W2100349140 @default.
- W2903586573 cites W2109838565 @default.
- W2903586573 cites W2110560983 @default.
- W2903586573 cites W2111978413 @default.
- W2903586573 cites W2114828923 @default.
- W2903586573 cites W2116047996 @default.
- W2903586573 cites W2116111392 @default.
- W2903586573 cites W2116117847 @default.
- W2903586573 cites W2121384790 @default.
- W2903586573 cites W2124318188 @default.
- W2903586573 cites W2128880918 @default.
- W2903586573 cites W2130957177 @default.
- W2903586573 cites W2139963479 @default.
- W2903586573 cites W2141052558 @default.
- W2903586573 cites W2141187709 @default.
- W2903586573 cites W2142350742 @default.
- W2903586573 cites W2148698435 @default.
- W2903586573 cites W2148734328 @default.
- W2903586573 cites W2153113745 @default.
- W2903586573 cites W2160876388 @default.
- W2903586573 cites W2161441832 @default.
- W2903586573 cites W2162705528 @default.
- W2903586573 cites W2164620627 @default.
- W2903586573 cites W2235442146 @default.
- W2903586573 cites W2311203695 @default.
- W2903586573 cites W2488318029 @default.
- W2903586573 cites W2499215009 @default.
- W2903586573 cites W2507299665 @default.
- W2903586573 cites W2529005926 @default.
- W2903586573 cites W2553552999 @default.
- W2903586573 cites W2563535234 @default.
- W2903586573 cites W2580900366 @default.
- W2903586573 cites W2582734618 @default.
- W2903586573 cites W2594262604 @default.
- W2903586573 cites W2730159810 @default.
- W2903586573 cites W2737351134 @default.
- W2903586573 cites W2781666580 @default.
- W2903586573 cites W2949672402 @default.
- W2903586573 cites W4238906737 @default.
- W2903586573 cites W4245598032 @default.
- W2903586573 cites W4245603874 @default.
- W2903586573 cites W4247000077 @default.
- W2903586573 doi "https://doi.org/10.1038/s41598-018-36428-7" @default.
- W2903586573 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6299273" @default.
- W2903586573 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30568252" @default.
- W2903586573 hasPublicationYear "2018" @default.
- W2903586573 type Work @default.
- W2903586573 sameAs 2903586573 @default.
- W2903586573 citedByCount "18" @default.
- W2903586573 countsByYear W29035865732019 @default.
- W2903586573 countsByYear W29035865732020 @default.
- W2903586573 countsByYear W29035865732021 @default.
- W2903586573 countsByYear W29035865732022 @default.
- W2903586573 countsByYear W29035865732023 @default.
- W2903586573 crossrefType "journal-article" @default.
- W2903586573 hasAuthorship W2903586573A5025434893 @default.
- W2903586573 hasAuthorship W2903586573A5039569420 @default.
- W2903586573 hasAuthorship W2903586573A5061765851 @default.
- W2903586573 hasBestOaLocation W29035865731 @default.
- W2903586573 hasConcept C104317684 @default.
- W2903586573 hasConcept C138025448 @default.
- W2903586573 hasConcept C141231307 @default.
- W2903586573 hasConcept C153957851 @default.
- W2903586573 hasConcept C193252679 @default.
- W2903586573 hasConcept C24586158 @default.
- W2903586573 hasConcept C54355233 @default.
- W2903586573 hasConcept C67705224 @default.