Matches in SemOpenAlex for { <https://semopenalex.org/work/W2903629076> ?p ?o ?g. }
- W2903629076 endingPage "478" @default.
- W2903629076 startingPage "463" @default.
- W2903629076 abstract "Abstract Background Human papillomavirus (HPV)‐positive oropharyngeal squamous cell carcinoma (OPSCC) is a highly immunogenic tumor and differences in tumor microenvironment might contribute to the improved survival of HPV‐positive OPSCC patient. Methods A comprehensive multivariate analysis with clinical and immune variables (human leukocyte antigen [HLA] I/II, programmed death ligand 1 (PD‐L1), programmed death receptor 1 (PD1), T cells, and macrophages) was performed in 142 OPSCC patients. Results We found an inverse correlation between the expression of HLA class II molecules on tumor cells and CD68+ CD163+ tumor‐associated macrophages (TAMs). High HLA‐DP/DQ/DR expression and low number of TAMs were associated with longer disease‐specific survival and disease‐free survival (DFS). Furthermore, a new population of CD8+ FoxP3+ T cells was correlated with shorter DFS in multivariate analysis. Conclusions We identified new prognostic markers for patients with oropharyngeal cancer, which can be used for selecting patients that can benefit from immunotherapy." @default.
- W2903629076 created "2018-12-22" @default.
- W2903629076 creator A5016627657 @default.
- W2903629076 creator A5028581150 @default.
- W2903629076 creator A5031117246 @default.
- W2903629076 creator A5033118574 @default.
- W2903629076 creator A5033758292 @default.
- W2903629076 creator A5054621707 @default.
- W2903629076 creator A5055202753 @default.
- W2903629076 creator A5062396602 @default.
- W2903629076 creator A5064418188 @default.
- W2903629076 creator A5073464444 @default.
- W2903629076 creator A5077969175 @default.
- W2903629076 date "2018-12-14" @default.
- W2903629076 modified "2023-10-05" @default.
- W2903629076 title "HLA class II expression on tumor cells and low numbers of tumor‐associated macrophages predict clinical outcome in oropharyngeal cancer" @default.
- W2903629076 cites W1752668680 @default.
- W2903629076 cites W1842119890 @default.
- W2903629076 cites W1972825083 @default.
- W2903629076 cites W1980485314 @default.
- W2903629076 cites W1989814127 @default.
- W2903629076 cites W2013407480 @default.
- W2903629076 cites W2019665726 @default.
- W2903629076 cites W2028525361 @default.
- W2903629076 cites W2032132846 @default.
- W2903629076 cites W2033278321 @default.
- W2903629076 cites W2035525012 @default.
- W2903629076 cites W2038981426 @default.
- W2903629076 cites W2042543697 @default.
- W2903629076 cites W2045578544 @default.
- W2903629076 cites W2046133556 @default.
- W2903629076 cites W2046847486 @default.
- W2903629076 cites W2048787584 @default.
- W2903629076 cites W2060320549 @default.
- W2903629076 cites W2061572018 @default.
- W2903629076 cites W2066912909 @default.
- W2903629076 cites W2067642458 @default.
- W2903629076 cites W2068467835 @default.
- W2903629076 cites W2076743146 @default.
- W2903629076 cites W2110435930 @default.
- W2903629076 cites W2110664940 @default.
- W2903629076 cites W2117692326 @default.
- W2903629076 cites W2119301589 @default.
- W2903629076 cites W2124904564 @default.
- W2903629076 cites W2128640763 @default.
- W2903629076 cites W2133123802 @default.
- W2903629076 cites W2139766596 @default.
- W2903629076 cites W2140633375 @default.
- W2903629076 cites W2142530756 @default.
- W2903629076 cites W2146906100 @default.
- W2903629076 cites W2225758346 @default.
- W2903629076 cites W2237325298 @default.
- W2903629076 cites W2284470477 @default.
- W2903629076 cites W2301707196 @default.
- W2903629076 cites W2344037260 @default.
- W2903629076 cites W2374246000 @default.
- W2903629076 cites W2517495788 @default.
- W2903629076 cites W2539222431 @default.
- W2903629076 cites W2556232360 @default.
- W2903629076 cites W2564105093 @default.
- W2903629076 cites W2582289619 @default.
- W2903629076 cites W2582686270 @default.
- W2903629076 cites W2590756052 @default.
- W2903629076 cites W2594615455 @default.
- W2903629076 cites W2610297465 @default.
- W2903629076 cites W2618283495 @default.
- W2903629076 cites W2648296251 @default.
- W2903629076 cites W2732036046 @default.
- W2903629076 cites W2737405537 @default.
- W2903629076 cites W4313333832 @default.
- W2903629076 doi "https://doi.org/10.1002/hed.25442" @default.
- W2903629076 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6519285" @default.
- W2903629076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30549362" @default.
- W2903629076 hasPublicationYear "2018" @default.
- W2903629076 type Work @default.
- W2903629076 sameAs 2903629076 @default.
- W2903629076 citedByCount "12" @default.
- W2903629076 countsByYear W29036290762019 @default.
- W2903629076 countsByYear W29036290762020 @default.
- W2903629076 countsByYear W29036290762021 @default.
- W2903629076 countsByYear W29036290762022 @default.
- W2903629076 crossrefType "journal-article" @default.
- W2903629076 hasAuthorship W2903629076A5016627657 @default.
- W2903629076 hasAuthorship W2903629076A5028581150 @default.
- W2903629076 hasAuthorship W2903629076A5031117246 @default.
- W2903629076 hasAuthorship W2903629076A5033118574 @default.
- W2903629076 hasAuthorship W2903629076A5033758292 @default.
- W2903629076 hasAuthorship W2903629076A5054621707 @default.
- W2903629076 hasAuthorship W2903629076A5055202753 @default.
- W2903629076 hasAuthorship W2903629076A5062396602 @default.
- W2903629076 hasAuthorship W2903629076A5064418188 @default.
- W2903629076 hasAuthorship W2903629076A5073464444 @default.
- W2903629076 hasAuthorship W2903629076A5077969175 @default.
- W2903629076 hasBestOaLocation W29036290761 @default.
- W2903629076 hasConcept C121608353 @default.
- W2903629076 hasConcept C126322002 @default.
- W2903629076 hasConcept C143998085 @default.
- W2903629076 hasConcept C147483822 @default.