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- W2903796564 abstract "Chemical investigation of the plant endophytic fungus Pestalotiopsis sp. afforded two new butenolides, pestalolides B and C (1 and 2), two new diphenyl ethers, pestalotethers E and F (3 and 4), together with seven known compounds (5–11). Their structures were established by extensive spectroscopic analyses and the absolute configuration of 1 was further confirmed by ECD calculation. Structurally, compound 1 represents the first example of a new type of butenolide derivatives, bearing an unprecedented carbon scaffold having 13 carbon atoms. Compounds 1–4 were evaluated for the cytotoxic activities, and compound 1 showed remarkable inhibitory potency against human tumor HL60, U87MG, MDA-MB-231, and HEP-3B cell lines, with IC50 values of 1.42, 5.90, 5.90, and 4.29 μM, respectively." @default.
- W2903796564 created "2018-12-22" @default.
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- W2903796564 date "2019-02-01" @default.
- W2903796564 modified "2023-10-18" @default.
- W2903796564 title "Cytotoxic butenolides and diphenyl ethers from the endophytic fungus Pestalotiopsis sp." @default.
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- W2903796564 doi "https://doi.org/10.1016/j.phytol.2018.11.021" @default.
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