Matches in SemOpenAlex for { <https://semopenalex.org/work/W2903831574> ?p ?o ?g. }
- W2903831574 endingPage "660" @default.
- W2903831574 startingPage "653" @default.
- W2903831574 abstract "Hybrid histidine kinase (HHKs) are widespread in fungi, but their roles in the regulation of fungal adaptation to environmental stresses remain largely unclear. To elucidate this, we cloned HisK2301 from Rhodosporidium kratochvilovae strain YM25235, characterized HisK2301 as a novel HHK, and further investigated the role of HisK2301 by overexpressing it in YM25235. Our results revealed that HisK2301 can promote adaptation of YM25235 to cold, osmotic, and salt stresses. During cold stress, HisK2301 significantly enhanced the biosynthesis of polyunsaturated fatty acids (PUFA) and intracellular glycerol. HisK2301 also augmented the expression levels of Δ12/Δ15 fatty acid desaturase (RKD12) and glycerol-3-phosphate dehydrogenase1 (GPD1), which are responsible for PUFA and glycerol biosynthesis, respectively. To conclude, our findings give the first insight into the defense and mechanisms of HisK2301 in fungi against cold stress and suggest the potential use of the novel cold-adapted HHK HisK2301 in industrial processes, such as large-scale production of PUFA." @default.
- W2903831574 created "2018-12-22" @default.
- W2903831574 creator A5016297315 @default.
- W2903831574 creator A5024437788 @default.
- W2903831574 creator A5029172602 @default.
- W2903831574 creator A5061032418 @default.
- W2903831574 creator A5067401695 @default.
- W2903831574 creator A5086525063 @default.
- W2903831574 date "2018-12-18" @default.
- W2903831574 modified "2023-10-18" @default.
- W2903831574 title "Novel Histidine Kinase Gene <i>HisK2301</i> from <i>Rhodosporidium kratochvilovae</i> Contributes to Cold Adaption by Promoting Biosynthesis of Polyunsaturated Fatty Acids and Glycerol" @default.
- W2903831574 cites W1743772167 @default.
- W2903831574 cites W1903949561 @default.
- W2903831574 cites W1912145551 @default.
- W2903831574 cites W1963867445 @default.
- W2903831574 cites W1965882216 @default.
- W2903831574 cites W1967383045 @default.
- W2903831574 cites W1969860458 @default.
- W2903831574 cites W1973394750 @default.
- W2903831574 cites W1981526282 @default.
- W2903831574 cites W1985640760 @default.
- W2903831574 cites W2002453663 @default.
- W2903831574 cites W2004908076 @default.
- W2903831574 cites W2006882494 @default.
- W2903831574 cites W2012241820 @default.
- W2903831574 cites W2032793307 @default.
- W2903831574 cites W2048834626 @default.
- W2903831574 cites W2049183549 @default.
- W2903831574 cites W2049614152 @default.
- W2903831574 cites W2054664724 @default.
- W2903831574 cites W2054932792 @default.
- W2903831574 cites W2064405226 @default.
- W2903831574 cites W2076923879 @default.
- W2903831574 cites W2077721821 @default.
- W2903831574 cites W2077986479 @default.
- W2903831574 cites W2081905674 @default.
- W2903831574 cites W2081929574 @default.
- W2903831574 cites W2093679408 @default.
- W2903831574 cites W2101406878 @default.
- W2903831574 cites W2102850224 @default.
- W2903831574 cites W2106132742 @default.
- W2903831574 cites W2107093868 @default.
- W2903831574 cites W2114439895 @default.
- W2903831574 cites W2118013428 @default.
- W2903831574 cites W2129335564 @default.
- W2903831574 cites W2134476079 @default.
- W2903831574 cites W2136623592 @default.
- W2903831574 cites W2140164333 @default.
- W2903831574 cites W2143202822 @default.
- W2903831574 cites W2146673384 @default.
- W2903831574 cites W2156264549 @default.
- W2903831574 cites W2159477430 @default.
- W2903831574 cites W2160315270 @default.
- W2903831574 cites W2163181687 @default.
- W2903831574 cites W2170068717 @default.
- W2903831574 cites W2280986517 @default.
- W2903831574 cites W2334137496 @default.
- W2903831574 cites W2560018015 @default.
- W2903831574 cites W2561203157 @default.
- W2903831574 cites W2610285500 @default.
- W2903831574 cites W2726398769 @default.
- W2903831574 cites W2767582447 @default.
- W2903831574 cites W2788464637 @default.
- W2903831574 doi "https://doi.org/10.1021/acs.jafc.8b04859" @default.
- W2903831574 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30558417" @default.
- W2903831574 hasPublicationYear "2018" @default.
- W2903831574 type Work @default.
- W2903831574 sameAs 2903831574 @default.
- W2903831574 citedByCount "8" @default.
- W2903831574 countsByYear W29038315742021 @default.
- W2903831574 countsByYear W29038315742022 @default.
- W2903831574 countsByYear W29038315742023 @default.
- W2903831574 crossrefType "journal-article" @default.
- W2903831574 hasAuthorship W2903831574A5016297315 @default.
- W2903831574 hasAuthorship W2903831574A5024437788 @default.
- W2903831574 hasAuthorship W2903831574A5029172602 @default.
- W2903831574 hasAuthorship W2903831574A5061032418 @default.
- W2903831574 hasAuthorship W2903831574A5067401695 @default.
- W2903831574 hasAuthorship W2903831574A5086525063 @default.
- W2903831574 hasConcept C181199279 @default.
- W2903831574 hasConcept C19038510 @default.
- W2903831574 hasConcept C2780881558 @default.
- W2903831574 hasConcept C543025807 @default.
- W2903831574 hasConcept C553450214 @default.
- W2903831574 hasConcept C55493867 @default.
- W2903831574 hasConcept C86803240 @default.
- W2903831574 hasConceptScore W2903831574C181199279 @default.
- W2903831574 hasConceptScore W2903831574C19038510 @default.
- W2903831574 hasConceptScore W2903831574C2780881558 @default.
- W2903831574 hasConceptScore W2903831574C543025807 @default.
- W2903831574 hasConceptScore W2903831574C553450214 @default.
- W2903831574 hasConceptScore W2903831574C55493867 @default.
- W2903831574 hasConceptScore W2903831574C86803240 @default.
- W2903831574 hasFunder F4320321001 @default.
- W2903831574 hasIssue "2" @default.
- W2903831574 hasLocation W29038315741 @default.
- W2903831574 hasLocation W29038315742 @default.
- W2903831574 hasOpenAccess W2903831574 @default.