Matches in SemOpenAlex for { <https://semopenalex.org/work/W2903835522> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2903835522 endingPage "606" @default.
- W2903835522 startingPage "599" @default.
- W2903835522 abstract "Aims Vaginal distention (VD) is a validated model of birth‐related trauma in rats. Recently a mouse VD model was reported. Our study was originally conducted to evaluate the impact of age on VD in mice. This manuscript describes the study and reports on the lack of reproducibility of VD models in mice. Methods We utilized female C57BL/6 mice. A total of 190, 12‐weeks old mice, were randomized into VD and sham groups. We inflated a modified Foley's balloon with 0.3 mL for 1 h inside the mice vagina. Afterwards, we measured the leak point pressure (LPP) at defined timepoints (0, 4, 10, 20, or 40 days). We randomized another 190, 40‐week old, C57BL/6 mice into either VD or sham groups. We used an extra 20 mice as age − matched controls. Results In both 12 and 40 weeks‐old mice, LPP was significantly decreased versus the negative controls at day 0. Additionally, in both 12 and 40 weeks‐old mice, the decrease in LPP was significantly higher in the VD group compared to the sham group at day 0. However, the LPP results were comparable between VD and sham at any other time point thereafter. Furthermore, there was no significant change in LPP values between instrumented (VD and sham) mice and control mice at any time after day 0. Conclusions The VD models previously described is not a reproducible model for the study of VD with large number of mice. Our results, unfortunately, do not support its use to study VD injury in mice." @default.
- W2903835522 created "2018-12-22" @default.
- W2903835522 creator A5020604234 @default.
- W2903835522 creator A5022277293 @default.
- W2903835522 creator A5048266063 @default.
- W2903835522 creator A5053597509 @default.
- W2903835522 creator A5067056604 @default.
- W2903835522 creator A5070091606 @default.
- W2903835522 date "2018-12-14" @default.
- W2903835522 modified "2023-09-25" @default.
- W2903835522 title "The vaginal distention model in mice is not a reliable model of simulated birth trauma‐induced stress urinary incontinence" @default.
- W2903835522 cites W1604629913 @default.
- W2903835522 cites W1966958168 @default.
- W2903835522 cites W1980242273 @default.
- W2903835522 cites W1996419739 @default.
- W2903835522 cites W1998527128 @default.
- W2903835522 cites W2016630348 @default.
- W2903835522 cites W2020473648 @default.
- W2903835522 cites W2022518740 @default.
- W2903835522 cites W2034224375 @default.
- W2903835522 cites W2038455131 @default.
- W2903835522 cites W2050826967 @default.
- W2903835522 cites W2057197945 @default.
- W2903835522 cites W2079241211 @default.
- W2903835522 cites W2088047761 @default.
- W2903835522 cites W2091207929 @default.
- W2903835522 cites W2108989940 @default.
- W2903835522 cites W2127092452 @default.
- W2903835522 cites W2137986237 @default.
- W2903835522 cites W2149043555 @default.
- W2903835522 cites W2149114324 @default.
- W2903835522 cites W2170740534 @default.
- W2903835522 cites W2172190121 @default.
- W2903835522 cites W2331209176 @default.
- W2903835522 cites W2340161707 @default.
- W2903835522 cites W2616793840 @default.
- W2903835522 cites W2781999545 @default.
- W2903835522 doi "https://doi.org/10.1002/nau.23886" @default.
- W2903835522 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30549310" @default.
- W2903835522 hasPublicationYear "2018" @default.
- W2903835522 type Work @default.
- W2903835522 sameAs 2903835522 @default.
- W2903835522 citedByCount "2" @default.
- W2903835522 countsByYear W29038355222022 @default.
- W2903835522 countsByYear W29038355222023 @default.
- W2903835522 crossrefType "journal-article" @default.
- W2903835522 hasAuthorship W2903835522A5020604234 @default.
- W2903835522 hasAuthorship W2903835522A5022277293 @default.
- W2903835522 hasAuthorship W2903835522A5048266063 @default.
- W2903835522 hasAuthorship W2903835522A5053597509 @default.
- W2903835522 hasAuthorship W2903835522A5067056604 @default.
- W2903835522 hasAuthorship W2903835522A5070091606 @default.
- W2903835522 hasConcept C126322002 @default.
- W2903835522 hasConcept C126894567 @default.
- W2903835522 hasConcept C141071460 @default.
- W2903835522 hasConcept C142724271 @default.
- W2903835522 hasConcept C204787440 @default.
- W2903835522 hasConcept C2775961468 @default.
- W2903835522 hasConcept C2777744392 @default.
- W2903835522 hasConcept C2778117688 @default.
- W2903835522 hasConcept C2778531004 @default.
- W2903835522 hasConcept C42407357 @default.
- W2903835522 hasConcept C71924100 @default.
- W2903835522 hasConceptScore W2903835522C126322002 @default.
- W2903835522 hasConceptScore W2903835522C126894567 @default.
- W2903835522 hasConceptScore W2903835522C141071460 @default.
- W2903835522 hasConceptScore W2903835522C142724271 @default.
- W2903835522 hasConceptScore W2903835522C204787440 @default.
- W2903835522 hasConceptScore W2903835522C2775961468 @default.
- W2903835522 hasConceptScore W2903835522C2777744392 @default.
- W2903835522 hasConceptScore W2903835522C2778117688 @default.
- W2903835522 hasConceptScore W2903835522C2778531004 @default.
- W2903835522 hasConceptScore W2903835522C42407357 @default.
- W2903835522 hasConceptScore W2903835522C71924100 @default.
- W2903835522 hasFunder F4320306080 @default.
- W2903835522 hasIssue "2" @default.
- W2903835522 hasLocation W29038355221 @default.
- W2903835522 hasLocation W29038355222 @default.
- W2903835522 hasOpenAccess W2903835522 @default.
- W2903835522 hasPrimaryLocation W29038355221 @default.
- W2903835522 hasRelatedWork W175436197 @default.
- W2903835522 hasRelatedWork W2003938723 @default.
- W2903835522 hasRelatedWork W2047967234 @default.
- W2903835522 hasRelatedWork W2118496982 @default.
- W2903835522 hasRelatedWork W2364998975 @default.
- W2903835522 hasRelatedWork W2369162477 @default.
- W2903835522 hasRelatedWork W2411790315 @default.
- W2903835522 hasRelatedWork W2439875401 @default.
- W2903835522 hasRelatedWork W4238867864 @default.
- W2903835522 hasRelatedWork W2525756941 @default.
- W2903835522 hasVolume "38" @default.
- W2903835522 isParatext "false" @default.
- W2903835522 isRetracted "false" @default.
- W2903835522 magId "2903835522" @default.
- W2903835522 workType "article" @default.